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Objective: To compare corneal endothelial indexes in eyes with pseudoexfoliation syndrome (PEX) and without it, and identify the dependence of corneal endothelial cell density (CD) on the age and stage of glaucoma.Patients and Methods: The study included 55 people (96 eyes). There were 53 eyes with PEX and 43 eyes without it. Patients were divided into 2 age groups: 40–60 years (41 eyes) and 61–80 years (55 eyes). The groups were homogeneous with respect to the level of IOP, Central corneal thickness, anteposterior axis of the eye and the stages of glaucoma. Endothelial microscopy was performed on a SP-3000P (Topcon). Statistical processing was made with "SPSS 16.0 for Windows"(methods of variation statistics, discriminant analysis).Results: There were significant difference in eyes with PEX and without PEX in CD in ages of 40–60 years (2309,57±87,77 cells/mm2 and 2642,39±64,81 cells/mm2, p=0.005) and 61–80 years (2247,02±59,5 (cells/mm2 and 2590,18±93,39 cells/mm2, p=0.004), as well as in the average surface area of endothelial cell (434,08±17,43 µm2 and 385,17±9,57 µm2, p=0,024; 461,14±15,23 µm2 and of 395.00±13,21 µm2, p=0.002, respectively).There was age difference of CD reduction: the highest CD was at 40–50 years (2722.75±63.05 cells/mm2), and at 81–90 years if fells to 1872.67±417.29 cells/mm2 (at a given age are found only patients with PEX). Revealed that the CD is dependent on the stage of glaucoma: the density was highest in the absence of glaucoma (2603.00±162.61 cells/mm2) and at an initial stage of glaucoma (2480.65±48.88 cells/mm2), while the density was lowest at stage 3 of glaucoma (2118.73±150.51 cells/mm2). Here reducing of the CD was due to patients with PEX, while in patients without PEX the differences were not statistically significant in different stages of glaucoma.Conclusion: Our study showed that the eyes with PEX are characterized by a more pronounced damage to the corneal endothelium, than eyes without it. The condition of endothelium cells worsens in eyes with PEX, depending on the age and stage of glaucoma. Thus, the performing of endothelial microscopy can be seen as a necessary tool in the monitoring of patients with PEG for the solution of a question on tactics of treatment and timely phacoemulsification.

Purpose. To determine the long-term status of the corneal endothelium after anterior radial keratotomy. Patients and methods. The main group consisted of 69 patients (104 eyes) who underwent radial or radial-tangential keratotomy to correct myopia and myopic astigmatism an average of 23,1±2,8 years ago (range 16 to 30 years). The average age of patients was 53,8±5,7 years (range 39 to 65 years). The number of keratotomy scars ranged from 4 to 14. Repeated keratotomy was performed on 8 eyes. The control group consisted of 56 patients (110 eyes) aged from 39 to 64 years(average 54,2±4,3 years) with refractive-axial myopia from medium to high stage, whom potentially could be done anterior keratotomy in the 90th of the last century. Patients with concomitant pathology and ocular trauma that could lead to loss ofendothelial cells were excluded from both groups. Corneal endothelium cell densit y, polimegatizm, pleomorphism in addition to standard eye examination were performed to all patients with the help of contactless endothelial microscope «EM-3000» company Tomey (Japan). Results. In the control group endothelial cell densit y averaged 2734,8±121,2 cells /mm2, in the main group — 2134,2±299,1 cells/mm2 (p