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Background: Diarrhoeal diseases are a major cause of death worldwide particularly among under-fives and probiotics is used in the management of diarrheal diseases. While some probiotics are of unproven usefulness, others are. Despite the burden of diarrhoea diseases in Africa; there is paucity of studies to support the efficacy or otherwise of S. boulardii among children with diarrheal disease. This study examined the impact of S. boulardii on the clinical course of acute watery diarrhea in children in a tertiary hospital in Nigeria. Methodology: Two hundred and fifty under-five children with acute watery diarrhoea were recruited and treated in the hospital. One hundred and twenty-five were given probiotics (S. boulardii) in addition to Oral Rehydration solution (ORS), zincand antibiotics while the other one hundred and twenty-five were noton probiotics (Controls). Their stool frequency on the 3rd and 5lh day and the duration of the diarrhea, were used to assess outcome. Information was obtained using a questionnaire and then analysed. Result: Majority of the children (58.8%) were at their second half of infancy (7-12 months). The average number of diarrheal episodes was significantly lower among the subjects by the 3rd day of intervention (t = 2.496, p = 0.013) but not by the 5"' day (t = 0.212; p = 0.832). Duration of diarrhea however, was not significantly different between the subjects and controls (p = 0.246). Conclusion:S. Boulardiionly probiotic preparations reduce the number of diarrhoeal episodes but not the duration of diarrhea among under- 5s. [ABSTRACT FROM AUTHOR]

Background: This study ascertained the level of distraction attributable to cell phone by drivers in Enugu. Methodology: This study was conducted in Enugu, Nigeria using a validated structured questionnaire randomly administered to drivers in different locations in the city. Study period was 2 months and different forms of distraction while driving were tested. Result: There were 500 participants in the study. 306(61.2%) were males and 194(38.8%) were females. The mean age of respondents was 43.85±9.89 years. Ninety-nine percent of respondents were aware of the ban on use of cell phones while driving but as much as 97.8% of the drivers still use cell phones while driving. Conclusion: Level of distracted driving in Enugu is quite high and this has the potential to cause serious road crashes which can impact negatively on the lives of the people. The need for concerted effort to educate people on the dangers of cell phone use while driving cannot be over emphasized. [ABSTRACT FROM AUTHOR]

Background: In children particularly in the developing world, there is a tendency to downplay the role of primary hypertension in their health. In adults, a number of factors have clearly been associated with the incidence of hypertension. Knowledge of the prevalence of hypertension and its associated factors among children in our environment is important and could inform the need for lifestyle changes and routine blood pressure (BP) checks in children so as to reduce BP-related health risks. Aim: The aim of this study is to document the prevalence of hypertension and its risk factors among children in Enugu, Nigeria. Materials and Methods: Children aged 6–17 years attending the outpatient clinic of a tertiary hospital, were enrolled for the study. Their socioeconomic status (SES), weight, height, BP, and dipstick urinalysis were measured using standardized methods. Adherence to Mediterranean diet was assessed using the Mediterranean Diet Quality Index (KIDMED). The prevalence of hypertension and the influence of these factors on their BP were analyzed. Results: Forty-six (9%) of the 491 participants had hypertension. Of these 46 hypertensive children, 72% were females while a significantly higher proportion 57% (P = 0.006), were in the age group 13–17 years. While age, gender, and the presence of protein in urine were significantly associated with hypertension in these children; body mass index, diet, family history of hypertension, and SES were not. Conclusion: The prevalence of hypertension in children in this environment is high and appears to be increasing. There is need for routine BP and urinalysis check for all children in our clinics and wards. [ABSTRACT FROM AUTHOR]

Background: Children with asthma (subjects), just as their non asthmatic colleagues, are expected to perform optimally academically and with a good intelligent score. A number of activities in children with asthma may be affected by asthmatic attacks including their education/academic performance. Report on academic performance and IQ of school children with asthma and comparisons with those without asthma (controls) within and outside Nigeria are scanty. Aims: This study compared the academic performance and IQ of asthmatics and nonasthmatic school children. Materials and Methods: One hundred and twenty children with asthma aged 5-11 years were consecutively recruited at the asthma clinic of UNTH Enugu and their age, gender and socio-economic class-matched normal classmates were enrolled as controls. Academic performance of the children with asthma was studied using the overall scores achieved in the three term examinations in the preceding academic year (2012/2013), while their IQ was determined using the Draw-A-Person-test. The findings were compared with that of the 120 controls. Results: The median (range) overall academic scores for the subjects 79.04% (36.08%-99.57%) was similar to that of controls 80.01% (50.65%-97.47%) (U = 6804, P = 0.461). However, a significant number of subjects compared to controls had poor academic performance. The mean IQ scores for subjects (123.28 ± 21.45) and controls (118.41 ± 19.87) did not differ significantly (t = 1.83; P = 0.069). There was also a significant and negative correlation (Pearson's) between age and mean DAPQ in both the subjects and controls (r = -0.377, P < 0.001; r = -0.492, P < 0.001 respectively. Conclusions: The intelligence scores and overall academic performance of children with asthma compares favorably with that of children without asthma. [ABSTRACT FROM AUTHOR]