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A recent study conducted at the Science University of Malaysia has explored Wegener's Granulomatosis, a rare multi-systemic illness with an unclear cause. The study presented a case of a 45-year-old male who initially experienced multiple episodes of epistaxis, followed by right facial nerve palsy and bilateral mixed hearing loss. Further investigations revealed opacities on the chest radiograph, which were initially suspected to be lung malignancy but were later diagnosed as Wegener's Granulomatosis through lung biopsy. This case is particularly interesting due to the diverse range of symptoms and the challenges in making an accurate diagnosis. [Extracted from the article]

A recent study conducted by researchers at the University of Cambridge Department of Medicine examined the use of rituximab in the treatment of microscopic polyangiitis, a type of vasculitis. The study compared the incidence of safety events and the time to first serious adverse event (SAE) between a group of patients treated with rituximab and a control group treated with non-rituximab therapies. The results showed that while the rituximab group had a shorter time to first SAE and a higher risk of infection, the differences in baseline characteristics between the two groups necessitate a careful interpretation of these findings. [Extracted from the article]

The article presents a case study of a 54-year-old man with Wegener's granulomatosis co-existing with antiphospholipid syndrome, presenting with rare skin manifestations and positive cytoplasmic antineutrophil cytoplasmic antibody (c-ANCA) and antiphospholipid antibodies. Topics include the complexity of autoimmune diseases, the role of comprehensive evaluation for accurate diagnosis, and the effective treatment approach involving prednisolone, cyclophosphamide, and anticoagulation.

A recent study conducted by researchers at Shahid Beheshti University of Medical Sciences highlights the potential relationship between streptococcal infection and cutaneous polyarteritis nodosa (PAN) in pediatric patients. The case report emphasizes the importance of considering PAN in children presenting with atypical symptoms such as migratory arthritis and subcutaneous nodules. Early recognition and prompt intervention, including addressing potential infectious triggers, are crucial for optimal outcomes in pediatric PAN. The study underscores the need for a multidisciplinary approach to effectively identify and manage this rare vasculitis disorder in the pediatric population. [Extracted from the article]

A recent study conducted by researchers at the Medical University of Sofia in Bulgaria focused on systemic vasculitis, a rare and heterogeneous disease that affects various organs and systems. The study aimed to evaluate ANCA-associated vasculitis in Bulgaria and found that the analyzed population represented approximately 60% of the patients in the country. The research highlighted the role of immune mechanisms in the pathogenesis of the disease and emphasized the importance of early diagnosis, as the disease is often diagnosed at an advanced stage. The study provides valuable epidemiological and clinical-pharmacological data on systemic vasculitis in Bulgaria. [Extracted from the article]

A recent study conducted at Khyber Teaching Hospital has provided new insights into lung diseases and conditions. The study focused on a case of microscopic polyangiitis (MPA), which is a type of vasculitis associated with the neutrophil cytoplasmic antibody (ANCA). The case involved a 65-year-old female with interstitial lung disease (ILD) who developed vasculitic skin lesions. The study highlights the importance of considering underlying vasculitis in patients with ILD and emphasizes the need for thorough diagnostic evaluation and multidisciplinary management. Early treatment of the underlying causes can help prevent complications such as skin manifestations. [Extracted from the article]

A recent report discusses research on systemic vasculitis, a rare disease that involves the inflammatory destruction of blood vessels. The research, conducted in Shymkent, Kazakhstan, by the South Kazakhstan Medical Academy, aims to improve the understanding and management of systemic vasculitis in the country. The study utilizes a comprehensive research approach, including retrospective and analytical methods, as well as an online survey. The researchers highlight the challenges in diagnosing systemic vasculitis and emphasize the importance of raising awareness among healthcare providers to prevent disability and improve patient outcomes. [Extracted from the article]

A study conducted by Northwell Health in Great Neck, New York, examined the outcomes of nasal reconstruction surgery in patients with Wegener's granulomatosis, a condition that causes nasal collapse and deformity. The study aimed to compare the functional and aesthetic outcomes of immediate versus delayed nasal reconstruction and measure the impact on psychosocial well-being. The results showed that immediate surgery led to superior functional and aesthetic scores and better psychosocial indicators compared to delayed surgery. The study suggests that immediate cartilaginous nasal reconstruction may be more beneficial than waiting for disease burnout before undergoing surgery. [Extracted from the article]

A recent report from the University of Aberdeen discusses the findings of a study on the delivery of intravenous treatments for ANCA-associated vasculitis. The study found significant variations in care and outcomes across different healthcare centers in the UK and Ireland. The research included a survey of 87 Vasculitis Society sites and 11 Scottish Health Boards, as well as interviews with healthcare professionals and patients. The study identified challenges in prescribing and delivering high-cost drugs, variations in how services delivered intravenous treatments, and the need for staff training and competencies. The researchers recommend ensuring timely access to urgent intravenous treatment within 7 days and providing national training modules for non-cancer chemotherapy. [Extracted from the article]

A recent study conducted at Guangxi Medical University in China explored the association between a gene polymorphism called Casitas B-lineage lymphoma (CBL) and the risk of microscopic polyangiitis (MPA) in a Chinese population. The study involved 266 MPA patients and 297 healthy controls. The results showed that a specific CBL gene variant, rs2276083, was associated with a decreased risk of MPA. Additionally, the study found potential interactions between CBL gene variants and other genes involved in MPA development. The researchers concluded that genetic polymorphisms in the CBL gene may play a role in the risk of MPA and its treatment effects in the Guangxi population in China. [Extracted from the article]

A recent report published in Drug Week discusses the findings of a case study on polyarteritis nodosa (PAN). PAN is a rare form of aggressive systemic vasculitis that primarily affects small-to-medium sized arteries, typically in the renal vasculature and other visceral organs. The report focuses on a specific case of cutaneous PAN (c-PAN), which is a less common variant that primarily affects the skin without systemic or visceral involvement. The researchers highlight the importance of prompt and appropriate treatment for systemic involvement, while noting that c-PAN has a more benign and chronic course that can be managed with low doses of oral steroids or anti-inflammatory drugs. The report concludes with a case study of a 33-year-old male who presented with c-PAN and was later found to have a renal infarct. For more information, readers can refer to the full article in the Asian Journal of Medical Sciences. [Extracted from the article]

Researchers at Akashi Medical Center in Japan have reported a case of immune-mediated necrotizing myopathy (IMNM) in a 77-year-old Japanese woman with microscopic polyangiitis (MPA). The patient presented with muscle weakness and myalgia, along with elevated serum creatinine kinase levels. A muscle biopsy confirmed IMNM, although tests for specific antibodies were negative. The study suggests that IMNM can be a result of muscle involvement in MPA. This research has been peer-reviewed and published in Internal Medicine. [Extracted from the article]

A recent report from the University of Pittsburgh discusses the epidemiology of infections and associated risk factors in patients with primary systemic vasculitides (PSV), a type of cardiovascular disease. The report highlights that infections are a leading cause of mortality in patients with PSV, with severe infection rates ranging from 16 to 40% in different cohorts. Risk factors for infections include older age, frailty, renal and pulmonary involvement, and a higher burden of comorbidities. Treatments such as higher cumulative doses of glucocorticoids are associated with an increased risk of infections, and mitigation strategies include screening, vaccination, and infection prophylaxis. The report emphasizes the importance of awareness of infection timing and types, as well as mitigation strategies, to ensure treatment success and survival for patients with PSV. [Extracted from the article]

A recent report from Seth GS Medical College and KEM Hospital in Maharashtra, India, discusses the case of a young girl who presented with multisystem symptoms that went undiagnosed for 11 years. After evaluation, she was found to have polyarteritis nodosa (PAN), a condition that mimics adenosine deaminase 2 deficiency. Whole-exome sequencing revealed a pathogenic variant in the gene, and the patient was treated with TNF alpha inhibitors, resulting in improvement. The study emphasizes the importance of accurate diagnosis and disease-specific therapy in relieving symptoms and reducing financial burden. [Extracted from the article]

A recent study conducted by researchers at the University of Aberdeen in the United Kingdom has found significant variations in the delivery of intravenous treatments for ANCA-associated vasculitis, a type of systemic vasculitis. The study involved a survey of 87 Vasculitis Society sites in the UK and Ireland, as well as interviews with healthcare professionals and patients. The findings revealed challenges in prescribing and delivering high-cost drugs, variations in how services delivered intravenous treatments, and average wait times for urgent IV treatment. The researchers recommend that healthcare organizations ensure timely access to treatment and provide appropriate training for staff. [Extracted from the article]

A patent application titled "Pharmaceutical Composition For Preventing Cytokine Storm" has been published online by the US Patent and Trademark Office. The patent application, filed by inventors from Kinki University in Japan, describes compounds that inhibit the activation of the NF-kB pathway and suppress the production of inflammatory cytokines such as TNFa and IL-6. These compounds have the potential to prevent cytokine storms, which are associated with severe respiratory distress and organ failure in diseases such as COVID-19, sepsis, and influenza. The pharmaceutical compositions could be administered orally, providing a potential treatment option for patients who cannot receive immediate medical care. [Extracted from the article]

A report from MedStar Georgetown University Hospital discusses research findings on polyarteritis nodosa (PAN), a systemic vasculitis that affects the blood vessels. The report highlights that PAN can also affect the coronary arteries, leading to significant morbidity and mortality. Traditional risk factors for atherosclerosis do not accurately predict the risk of coronary involvement in PAN. Advanced angiographic methods are needed to distinguish between atherosclerosis and arteritis. Treatment options include anticoagulation, immunosuppression, and revascularization, with coronary artery bypass grafting (CABG) offering definitive therapy when graft selection avoids the affected vascular territory. The report emphasizes the importance of recognizing clinical symptoms that may indicate coronary involvement in PAN. [Extracted from the article]

A recent study conducted by researchers at Kyoto University Graduate School of Medicine in Japan aimed to identify the risk factors associated with serious infections and infection-related mortality in patients with microscopic polyangiitis (MPA). The study found that advanced age, elevated C-reactive protein levels, and higher glucocorticoid dose ratios were independent risk factors for serious infections. Older age was also associated with infection-related deaths. The researchers suggest that strategies such as rapid glucocorticoid dose tapering may help mitigate the risk of infections in these patients. [Extracted from the article]

A recent study conducted by the National Institutes of Arthritis and Musculoskeletal and Skin Diseases in Bethesda, Maryland, provides new insights into Giant Cell Arteritis (GCA) and its association with clonal hematopoiesis (CH). The study found that CH, characterized by somatic mutations in hematopoietic cells, was detected in 34% of patients with GCA, compared to 18% of age-matched controls. The prevalence of CH was independently associated with age and vasculitis, occurring most frequently in patients with GCA. The research suggests that while CH may contribute to inflammation, it is not likely a primary causal factor in systemic vasculitis. [Extracted from the article]

Researchers from the Institute for Health Sciences at the Federal University of Bahia in Brazil have published a report on a case of a patient with cutaneous polyarteritis nodosa (cPAN) who developed dysautonomia. The patient, a 75-year-old male, presented with recurrent ulcers on his lower limbs. A skin biopsy confirmed the diagnosis of cPAN, and treatment with medication resulted in the healing of the ulcers. However, after two years, the patient experienced episodes of syncope, leading to a diagnosis of dysautonomia. This case highlights the possibility of cPAN evolving into a systemic condition. [Extracted from the article]

A new report from the Rheumatology Department discusses Wunderlich's syndrome, a rare complication of polyarteritis nodosa (PAN). The report presents a case study of a 48-year-old male who experienced symptoms such as leg muscle tenderness, flank pain, skin lesions, weight loss, and difficult-to-control hypertension. After a diagnosis of PAN, the patient received treatment with intravenous methylprednisolone and showed a good response. The researchers emphasize the importance of early diagnosis and aggressive treatment for improving clinical outcomes in cases of Wunderlich's syndrome. [Extracted from the article]

A recent study conducted in Orumiyeh, Iran, has reported new findings on Churg-Strauss Syndrome (CSS), also known as eosinophilic granulomatosis with polyangiitis (EGPA). CSS is a rare form of systemic vasculitis characterized by extravascular granulomas in patients with asthma and tissue eosinophilia. The study focused on a 45-year-old asthmatic male who presented with a cerebrovascular accident and was found to have a large left ventricular granuloma. The researchers recommend routine echocardiographic evaluation for patients with EGPA, as cardiac involvement is associated with a poor prognosis. [Extracted from the article]

A new study conducted at Tehran University of Medical Sciences examines the clinical manifestations of Wegener granulomatosis (WG) in Iranian ethnicities. The study analyzed data from 164 patients recorded between 2013 and 2018, focusing on demographics, symptoms, and the Birmingham Vasculitis Activity Score (BVAS). The findings indicate that the sinus, nose, lungs, and ears were the most commonly affected sites, while gastrointestinal and cardiac involvement were less common. The study also found that the clinical manifestations among Iranian ethnicities were similar, with the Gilaki ethnicity having the highest BVAS due to the humid weather in their region. [Extracted from the article]

A patent application has been made available online for a potential treatment for Kawasaki disease, a febrile eruptive disease in children. The application discusses the use of the Mcm8-CGAS-STING-IFN-I signal pathway as a disease target and proposes the use of a reagent for diagnosing the disease by detecting the gene expression or protein activity of MCM8. The application also describes the use of substances to improve the gene expression or protein activity of MCM8 for prevention and treatment. Additionally, the application discusses the use of antiplatelet agents in the treatment of viral infections, specifically targeting RNA viruses, and explores the potential use of antiplatelet agents in combination with other drugs and therapies. This research has implications for various fields including virology, cardiology, and pediatrics. [Extracted from the article]

A recent study conducted at National Cheng Kung University in Taiwan has investigated the association between autoimmune inflammatory rheumatic diseases (AIIRDs) and the risk of ischemic stroke at a young age. The study utilized the National Health Insurance Research Database in Taiwan to establish cohorts of patients with AIIRDs and compared them with a control group. The results showed that patients under 50 years old with systemic lupus erythematosus, systemic sclerosis, or systemic vasculitis have a significantly higher risk of developing ischemic stroke. Further research is needed to understand the underlying mechanisms of accelerated atherosclerosis in these AIIRDs. [Extracted from the article]

A recent report from the City University of New York (CUNY) provides new insights into central nervous system disorders, specifically systemic vasculitis and headache. Vasculitis refers to inflammation of blood vessels and can lead to injury and disability if left untreated. Headache is an important clue to vasculitic involvement of the central nervous system (CNS). Prompt evaluation and treatment are necessary to prevent progression and cerebral ischemia or infarction. The report highlights progress in the pathogenesis, diagnosis, and treatment of primary adult and pediatric CNS vasculitides. [Extracted from the article]

A report from the University of Lubeck in Germany discusses research findings on microscopic polyangiitis, a type of autoimmune disease. Microscopic polyangiitis is characterized by systemic necrotizing small-vessel vasculitis, which can affect any organ. The report explains that granulomatosis with polyangiitis (GPA) and microscopic polyangiitis (MPA) are two entities of ANCA-associated vasculitis (AAV), with GPA typically affecting the respiratory tract and MPA commonly affecting the upper respiratory tract. Treatment for these conditions depends on disease activity and the severity of organ involvement. This research has been peer-reviewed and provides valuable insights into the understanding and management of microscopic polyangiitis. [Extracted from the article]

A recent study conducted at Queen Elizabeth Hospital explored the topic of polyarteritis nodosa (PAN), a medium-sized vessel vasculitis that can present as both stenotic and aneurysmal lesions. The researchers reported a case of PAN in a patient with a history of cutaneous vasculitis, presenting with multiple territory ischemic stroke, mesenteric panniculitis, and coronary artery stenosis. The patient also had antiphospholipid antibody (aPL) positivity and was treated with immunosuppressants and anticoagulation. The study discusses the clinical manifestation of PAN and its association with aPL. [Extracted from the article]

A recent study published in the journal Medicine discusses a case of a patient who developed end-stage renal disease (ESRD) after receiving the third dose of the mRNA-1273 vaccine for SARS-CoV2. The patient experienced symptoms such as anuria, fatigue, anorexia, and nausea, and was diagnosed with microscopic polyangiitis (MPA) and atypical hemolytic-uremic syndrome (aHUS). Despite treatment, the patient still required hemodialysis three months after discharge. The study suggests a potential link between the vaccine and the development of MPA and aHUS, but further research is needed to understand the mechanisms and variables involved. [Extracted from the article]

A study conducted by Yonsei University College of Medicine investigated the clinical implications of peripheral eosinophil count at diagnosis in patients with microscopic polyangiitis (MPA) and granulomatosis with polyangiitis (GPA). The study included 224 patients who were newly diagnosed with MPA and GPA and had a peripheral eosinophil count at diagnosis of less than 1,000/mm3. The researchers found that peripheral eosinophil count at diagnosis was significantly correlated with disease activity and all-cause mortality during follow-up. Patients with higher eosinophil counts at diagnosis had a lower survival rate. This study provides valuable insights into the prognosis and management of MPA and GPA patients. [Extracted from the article]

Researchers from Vrije Universiteit Brussel (VUB) have conducted a study on the hepatitis B virus (HBV) and its association with polyarteritis nodosa (PAN), a form of necrotizing vasculitis. PAN primarily affects medium-sized vessels but can also involve smaller vessels. The clinical presentation of PAN is diverse, with symptoms such as asthenia, fever, and unintended weight loss. While PAN was historically linked to HBV infection, this association has declined in recent years. Current research suggests connections between PAN and genetic syndromes and neoplasia. The study provides a comprehensive review of PAN, focusing on the progression of its clinical manifestations over time. [Extracted from the article]

A study conducted by researchers at Manipal Academy of Higher Education in Karnataka, India, explores the topic of microscopic polyangiitis (MPA), an autoimmune disease that affects small blood vessels. The study focuses on a case of a 63-year-old woman who was diagnosed with MPA primarily affecting her lungs and middle ears. The researchers emphasize the importance of early diagnosis and treatment for MPA, as delayed diagnosis can occur due to atypical presentations and clinical features that resemble other conditions. The study highlights the use of monoclonal antibody therapy as a successful treatment for MPA. [Extracted from the article]

A new report from Shanghai Jiao Tong University School of Medicine provides fresh data on microscopic polyangiitis (MPA), a type of autoimmune disease. The study analyzed 436 patients with anti-neutrophil cytoplasmic antibody (ANCA)-associated vasculitides, of which 90 were diagnosed with MPA and underwent renal biopsy. The researchers identified four subtypes of MPA with distinct clinical manifestations and prognoses: renal impairment type, pure type, systemic inflammation type, and rapid progress type. The study found that the renal impairment type had the poorest prognosis, while the pure type had the best prognosis. The research highlights the importance of classifying MPA subtypes for better understanding and management of the disease. [Extracted from the article]

A study conducted by researchers at Shinshu University School of Medicine in Matsumoto, Japan, has found that serum sulfatide levels are associated with severe systemic vasculitis (SV) with kidney involvement. SV diseases are autoimmune diseases that often affect the kidneys and can lead to kidney dysfunction and end-stage kidney disease. The study analyzed the serum sulfatide levels of patients with different SV diseases and found that patients with more severe SV had lower levels of serum sulfatides. The researchers concluded that serum sulfatide levels may be a useful marker for assessing the severity of SV with kidney involvement. [Extracted from the article]

A study conducted by researchers at Ahvaz Jundishapur University of Medical Sciences in Iran discusses the deficiency of adenosine deaminase 2 (DADA2) as a challenging differential diagnosis of polyarteritis nodosa (PAN). DADA2 is an autosomal recessive monogenic disease caused by loss-of-function variants in the ADA2 gene. It affects small- and medium-sized vessels and presents with PAN-like features such as livedoid rash, early-onset stroke, hypogammaglobulinemia, hematological abnormalities, and systemic inflammation. Early diagnosis and treatment are crucial, with tumor necrosis factor (TNF)-inhibitors being the first-line treatment. However, further studies are needed to understand the genotype-phenotype associations and exact pathophysiology of DADA2. [Extracted from the article]

A recent study conducted by researchers at Peking Union Medical College Hospital in Beijing, China, has highlighted the importance of considering lymphoma as a potential diagnosis in patients with atypical mononeuropathy multiplex. The study focused on a case of extranodal NK/T-cell lymphoma (ENKTL) that initially presented with purpura-like rashes and foot drops, later developing peripheral nerve involvement. The researchers found that the initial symptoms resembled systemic vasculitis, leading to a misdiagnosis. This case emphasizes the need for careful consideration of lymphoma in patients with unusual neurological symptoms. [Extracted from the article]

A recent study conducted by the Department of Vascular Surgery has found that sirolimus-coated balloon angioplasty shows promise as a treatment for critical limb-threatening ischemia (CLTI) caused by polyarteritis nodosa (PAN). PAN is a rare form of vasculitis, and CLTI is a rare complication of the disease. The study describes a case of a 37-year-old woman with PAN who developed foot gangrene despite multiple treatments, including plain old balloon angioplasty (POBA). The use of a sirolimus-coated balloon during her third angioplasty resulted in successful limb salvage, with the patient remaining ulcer-free at 17 months after the procedure. This research suggests that sirolimus-coated balloon angioplasty may be a promising approach for treating PAN-induced CLTI. [Extracted from the article]

A study conducted at the First Affiliated Hospital in Ningbo, China, examined the association between microscopic polyangiitis (MPA) and pulmonary involvement, specifically interstitial lung disease (ILD) and bronchiectasis (BE). The study found that ILD and BE can be considered preexisting comorbidities of MPA, and that elevated serum creatinine levels were associated with shorter survival. However, treatment with glucocorticoids and/or immunosuppressants may improve outcomes for patients with MPA. The study highlights the importance of understanding the clinical characteristics and prognosis of MPA with pulmonary involvement for effective clinical management. [Extracted from the article]

A recent study conducted by researchers at Yonsei University in Seoul, South Korea, explored the expression of IL-6 receptors on T cells and the levels of soluble IL-6 receptors in patients with microscopic polyangiitis (MPA) and granulomatosis with polyangiitis (GPA). The study found that serum IL-6 levels were correlated with disease activity, but IL-6 receptor expression on T cells did not differ based on disease activity. However, stimulated T cells showed reduced IL-6 receptor expression compared to unstimulated conditions. Patients with active disease had higher levels of soluble IL-6 receptors than those with inactive disease, suggesting the potential for targeting soluble IL-6 receptors as a therapeutic approach. [Extracted from the article]

A case report from Dongfang Hospital of Beijing University of Chinese Medicine discusses the use of acupuncture as a treatment for rheumatoid vasculitis (RV) complicated by a refractory foot ulcer. RV is a common complication of rheumatoid arthritis (RA) and can result in severe skin vasculitis lesions. In this case, a 62-year-old man with RV developed a foot ulcer that did not respond to traditional treatments. After 12 weeks of acupuncture, the foot ulcer completely healed. The researchers suggest that acupuncture may be a viable alternative treatment for wounds that do not respond to traditional therapies. [Extracted from the article]

Keywords: Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis; Autoimmune Diseases and Conditions; Cardiovascular Diseases and Conditions; Health and Medicine; Microscopic Polyangiitis; Myeloid Cells; Systemic Vasculitis EN Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis Autoimmune Diseases and Conditions Cardiovascular Diseases and Conditions Health and Medicine Microscopic Polyangiitis Myeloid Cells Systemic Vasculitis 974 974 1 11/06/23 20231106 NES 231106 2023 NOV 6 (NewsRx) -- By a News Reporter-Staff News Editor at Cardiovascular Week -- Investigators publish new report on microscopic polyangiitis. MPA and GPA patients with sTREM-1 474.1 pg/mL exhibited a significantly higher risk for the upper half of BVAS than those without (relative risk 5.932).". [Extracted from the article]

For more information on this research see: Prediction Model for Respiratory-related Mortality In Microscopic Polyangiitis With Interstitial Lung Disease: Multicentre Reveal Cohort Study. Keywords: Osaka; Japan; Asia; Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis; Autoimmune Diseases and Conditions; Cardiovascular Diseases and Conditions; Clinical Research; Clinical Trials and Studies; Health and Medicine; Interstitial Lung Disease; Lung Diseases and Conditions; Microscopic Polyangiitis; Respiratory Tract Diseases and Conditions; Risk and Prevention; Systemic Vasculitis EN Osaka Japan Asia Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis Autoimmune Diseases and Conditions Cardiovascular Diseases and Conditions Clinical Research Clinical Trials and Studies Health and Medicine Interstitial Lung Disease Lung Diseases and Conditions Microscopic Polyangiitis Respiratory Tract Diseases and Conditions Risk and Prevention Systemic Vasculitis 691 691 1 10/16/23 20231016 NES 231016 2023 OCT 16 (NewsRx) -- By a News Reporter-Staff News Editor at Cardiovascular Week -- A new study on Respiratory Tract Diseases and Conditions - Lung Diseases and Conditions is now available. [Extracted from the article]

Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis, Autoimmune Diseases and Conditions, Biomarkers, Blood Proteins, Cardiovascular Diseases and Conditions, Complement C4, Diagnostics and Screening, Health and Medicine, Immunology, Kidney, Kidney Disease, Kidney Diseases and Conditions, Microscopic Polyangiitis, Complement System Proteins, Nephrology, Risk and Prevention, Systemic Vasculitis Keywords: Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis; Autoimmune Diseases and Conditions; Biomarkers; Blood Proteins; Cardiovascular Diseases and Conditions; Complement C4; Complement System Proteins; Diagnostics and Screening; Health and Medicine; Immunology; Kidney; Kidney Disease; Kidney Diseases and Conditions; Microscopic Polyangiitis; Nephrology; Risk and Prevention; Systemic Vasculitis EN Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis Autoimmune Diseases and Conditions Biomarkers Blood Proteins Cardiovascular Diseases and Conditions Complement C4 Complement System Proteins Diagnostics and Screening Health and Medicine Immunology Kidney Kidney Disease Kidney Diseases and Conditions Microscopic Polyangiitis Nephrology Risk and Prevention Systemic Vasculitis 716 716 1 10/09/23 20231009 NES 231009 2023 OCT 9 (NewsRx) -- By a News Reporter-Staff News Editor at Cardiovascular Week -- Fresh data on microscopic polyangiitis are presented in a new report. [Extracted from the article]

Keywords: Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis; Autoimmune Diseases and Conditions; Cardiovascular Diseases and Conditions; Clinical Research; Clinical Trials and Studies; Health and Medicine; Interstitial Lung Disease; Lung Diseases and Conditions; Microscopic Polyangiitis; Respiratory Tract Diseases and Conditions; Risk and Prevention; Systemic Vasculitis EN Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis Autoimmune Diseases and Conditions Cardiovascular Diseases and Conditions Clinical Research Clinical Trials and Studies Health and Medicine Interstitial Lung Disease Lung Diseases and Conditions Microscopic Polyangiitis Respiratory Tract Diseases and Conditions Risk and Prevention Systemic Vasculitis 317 317 1 09/11/23 20230911 NES 230911 2023 SEP 11 (NewsRx) -- By a News Reporter-Staff News Editor at Clinical Trials Week -- Data detailed on lung diseases and conditions have been presented. Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis, Autoimmune Diseases and Conditions, Cardiovascular Diseases and Conditions, Clinical Research, Clinical Trials and Studies, Health and Medicine, Interstitial Lung Disease, Lung Diseases and Conditions, Microscopic Polyangiitis, Respiratory Tract Diseases and Conditions, Risk and Prevention, Systemic Vasculitis. [Extracted from the article]

According to news reporting originating from Brest, France, by NewsRx correspondents, research stated, "Granulomatosis with polyangiitis (GPA) and microscopic polyangiitis (MPA) are antineutrophilic cytoplasmic antibody (ANCA)-associated vasculitides (AAV) that cause inflammation and necrosis of the small blood vessels, leading to downstream ischemia and organ damage. Brest, France, Europe, Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis, Autoimmune Diseases and Conditions, Cardiovascular Diseases and Conditions, Health and Medicine, Inflammation, Risk and Prevention, Systemic Vasculitis, Microscopic Polyangiitis Keywords: Brest; France; Europe; Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis; Autoimmune Diseases and Conditions; Cardiovascular Diseases and Conditions; Health and Medicine; Inflammation; Microscopic Polyangiitis; Risk and Prevention; Systemic Vasculitis EN Brest France Europe Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis Autoimmune Diseases and Conditions Cardiovascular Diseases and Conditions Health and Medicine Inflammation Microscopic Polyangiitis Risk and Prevention Systemic Vasculitis 374 374 1 08/14/23 20230814 NES 230814 2023 AUG 14 (NewsRx) -- By a News Reporter-Staff News Editor at Clinical Trials Week -- Current study results on Autoimmune Diseases and Conditions - Microscopic Polyangiitis have been published. [Extracted from the article]

Keywords: Cardiovascular Diseases and Conditions; Health and Medicine; Hematology; Hemic and Immune Systems; Immunology; Lymph Nodes; Lymphadenopathy; Lymphoid Tissue; Systemic Vasculitis; Vascular Diseases and Conditions; Vasculitis EN Cardiovascular Diseases and Conditions Health and Medicine Hematology Hemic and Immune Systems Immunology Lymph Nodes Lymphadenopathy Lymphoid Tissue Systemic Vasculitis Vascular Diseases and Conditions Vasculitis 148 148 1 08/07/23 20230807 NES 230807 2023 AUG 7 (NewsRx) -- By a News Reporter-Staff News Editor at Hematology Week -- Fresh data on systemic vasculitis are presented in a new report. According to the news editors, the research concluded: "Superficial lymphadenopathy is very rare in ANCA-associated systemic vasculitis. [Extracted from the article]

Keywords: Madrid; Spain; Europe; Cardiovascular Diseases and Conditions; Health and Medicine; Systemic Vasculitis; Vascular Diseases and Conditions; Vasculitis EN Madrid Spain Europe Cardiovascular Diseases and Conditions Health and Medicine Systemic Vasculitis Vascular Diseases and Conditions Vasculitis 721 721 1 07/31/23 20230731 NES 230731 2023 JUL 31 (NewsRx) -- By a News Reporter-Staff News Editor at Cardiovascular Week -- Current study results on Cardiovascular Diseases and Conditions - Systemic Vasculitis have been published. Keywords for this news article include: Madrid, Spain, Europe, Cardiovascular Diseases and Conditions, Health and Medicine, Systemic Vasculitis, Vascular Diseases and Conditions, Vasculitis, Foundation Jimenez Diaz University Hospital. [Extracted from the article]

The main autoantibodies, important not only in the diagnosis but also in monitoring and prognosis of systemic vasculitides, are anti-neutrophil cytoplasmic antibodies (ANCA), anti-glomerular basement membrane antibodies (anti-GBM), anti-complement component C1q antibodies (anti-C1q), and cryoglobulins." Keywords: Antibodies; Autoantibodies; Blood Proteins; Cardiovascular Diseases and Conditions; Diagnostics and Screening; Health and Medicine; Immunoglobulins; Immunology; Immunoproteins; Proteins; Serum Globulins; Systemic Vasculitis; Vascular Diseases and Conditions; Vasculitis EN Antibodies Autoantibodies Blood Proteins Cardiovascular Diseases and Conditions Diagnostics and Screening Health and Medicine Immunoglobulins Immunology Immunoproteins Proteins Serum Globulins Systemic Vasculitis Vascular Diseases and Conditions Vasculitis 495 495 1 07/31/23 20230731 NES 230731 2023 JUL 31 (NewsRx) -- By a News Reporter-Staff News Editor at Cardiovascular Week -- Investigators discuss new findings in systemic vasculitis. [Extracted from the article]

According to the news reporters, the research concluded: "This review of three cases of CPA-related enteritis, including our case, suggests that prompt CPA discontinuation and intensive systemic management are necessary when patients have gastrointestinal symptoms after CPA administration." Keywords: Fukushima; Japan; Asia; Alkylating Agents; Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis; Antineoplastics; Autoimmune Diseases and Conditions; Cardiovascular Diseases and Conditions; Cyclophosphamide; Cyclophosphamide Therapy; Digestive System Diseases and Conditions; Drugs and Therapies; Enteritis; Gastroenteritis; Gastrointestinal Diseases and Conditions; Health and Medicine; Hydrocarbons; Microscopic Polyangiitis; Mustard Compounds; Organophosphorus Compounds; Pharmaceuticals; Phosphoramide Mustards; Systemic Vasculitis EN Fukushima Japan Asia Alkylating Agents Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis Antineoplastics Autoimmune Diseases and Conditions Cardiovascular Diseases and Conditions Cyclophosphamide Cyclophosphamide Therapy Digestive System Diseases and Conditions Drugs and Therapies Enteritis Gastroenteritis Gastrointestinal Diseases and Conditions Health and Medicine Hydrocarbons Microscopic Polyangiitis Mustard Compounds Organophosphorus Compounds Pharmaceuticals Phosphoramide Mustards Systemic Vasculitis 230 230 1 07/10/23 20230714 NES 230714 2023 JUL 10 (NewsRx) -- By a News Reporter-Staff News Editor at Drug Week -- A new study on Autoimmune Diseases and Conditions - Microscopic Polyangiitis is now available. [Extracted from the article]