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The article from Poznan University of Medical Sciences presents new findings on the role of leptin receptor isoforms in adrenal tumors, showing their diagnostic and prognostic significance. Topics discussed include the use of leptin receptor variants as markers for carcinoma and prognosis, the correlation between receptor expressions and survival rates, and the impact of leptin on cell proliferation.

The article discusses a new clinical trial, examining the safety of switching from metreleptin to mibavademab in patients with generalized lipodystrophy. Topics include the evaluation of side effects from mibavademab, measurement of drug levels in the blood, and the potential development of antibodies against the drug.

A meta-analysis conducted by researchers at Hubei University of Medicine in China examined the association between leptin receptor (LEPR) gene polymorphisms and the risk of polycystic ovary syndrome (PCOS). The analysis included 11 studies and found that there was no significant association between the rs1137101 A/G polymorphism and PCOS risk in the general population. However, a significant association was observed in the Asian population. Similar positive associations were also found for the rs1805096 polymorphism. The researchers concluded that more well-designed studies with larger sample sizes are needed to verify these results. [Extracted from the article]

The patent application titled "Compositions and Methods for Enhancing Body Weight and Lean Muscle Mass Using Antagonists Against Leptin Receptor, GDF8 and Activin A" discusses a combination of antagonists that can be used to increase body weight, muscle strength, and lean mass in individuals who are malnourished, have eating disorders, or are undergoing physical therapy. The combination includes antagonists against the leptin receptor, GDF8, and Activin A. The invention also provides methods for increasing athletic performance and treating conditions such as malnutrition, cachexia, and muscle atrophy. The patent application provides detailed descriptions of the specific antibodies and compositions used in the combination. [Extracted from the article]

A recent study conducted at the University of Michigan-Ann Arbor has found that glutamatergic neurotransmission from leptin receptor cells is necessary for normal puberty and reproductive function in female mice. The researchers used designer drugs to stimulate neurons in the hypothalamic ventral premammillary nucleus (PMv) and observed an increase in luteinizing hormone (LH) release. Mice with a deletion of the Vglut2 gene in leptin receptor neurons showed delayed puberty, disrupted estrous cycles, and impaired gonadotropin-releasing hormone (GnRH) release. The study suggests that glutamate is required for the actions of leptin on pubertal development through PMv neurons. [Extracted from the article]

A recent report from the University of North Carolina Chapel Hill discusses the search for reliable biomarkers for anorexia nervosa (AN). The researchers conducted a systematic literature search and found that certain biomarkers were significantly higher in cases of AN compared to non-AN controls, while others were significantly lower. These findings suggest that peripheral biomarkers may be linked to the pathophysiology of AN and could potentially lead to breakthroughs in personalized clinical care for the disorder. The full report can be accessed for free online. [Extracted from the article]

A report from the Defence Institute of Physiology and Allied Sciences in Delhi, India, discusses the dysregulation of metabolic processes and its impact on the development of metabolic diseases. The research focuses on the role of hormones, particularly leptin, in regulating food intake and energy expenditure. The study also identifies specific genes and microRNAs that play a crucial role in leptin signaling and appetite regulation. The findings suggest that targeting these microRNAs could be useful in developing novel therapeutics for metabolic diseases. [Extracted from the article]

A recent study conducted by researchers at the University of Seville in Spain has found that morbid obesity is often accompanied by non-alcoholic fatty liver disease (NAFLD). The study examined the expression of genes related to reverse cholesterol transport and leptin receptor pathways in peripheral blood mononuclear cells (PBMCs) from patients with morbid obesity before and after gastric bypass surgery. The researchers discovered that the expression of these genes was decreased in patients with morbid obesity compared to non-obese subjects. The findings suggest that alterations in these pathways may play a role in the development of NAFLD in morbidly obese individuals. [Extracted from the article]

A recent report discusses research on obesity, specifically the potential benefits of combining long-acting PYY and GLP-1 receptor agonists as a treatment. The study conducted on diet-induced obese mice found that the combination treatment resulted in increased expression of genes involved in appetite regulation and improved sensitivity to leptin. These findings suggest that the synergistic effects of PYY and GLP-1 receptor agonists may contribute to weight loss. The research was conducted by Novo Nordisk and funded by the Innovation Fund. [Extracted from the article]

According to a preprint abstract, researchers have found that the absence of cannabinoid type 2 (CB2) receptors in animals leads to enhanced inflammation and pain in chronic pain models. The researchers hypothesized that CB2 receptor deficiency may also affect peripheral neuroinflammation caused by a high-fat diet (HFD). Interestingly, CB2 knockout animals showed resistance to HFD-induced neuroinflammation, while wild-type animals experienced hypersensitivity. These findings suggest that CB2 receptors may have a dual role in regulating inflammation and immune system function, depending on the cause of the inflammation. However, it is important to note that this research has not yet undergone peer review. [Extracted from the article]

A recent study conducted by researchers at the University of Iowa explores the role of the central autonomic network in the development of obesity-induced hypertension. The study focuses on the leptin receptor neurons and their involvement in cardiovascular and metabolic regulation. Through experiments on mice, the researchers identified shared neurons in various brain regions associated with the kidneys, liver, and brown adipose tissue. The findings suggest that leptin may play a role in coupling cardiovascular and metabolic functions through a small number of neurons in the central nervous system. [Extracted from the article]

A recent study from the University of Iowa explores the role of adipokines, specifically leptin, in cardiovascular and respiratory functions. The researchers focused on the lateral hypothalamic area (LHA), which is known as the "feeding center" of the brain. Through experiments on mice, they found that activation of LHA leptin receptors increased blood pressure, heart rate, respiratory rate, and minute ventilation. These findings suggest that the LHA may serve as a crucial node through which leptin influences cardiorespiratory control. The study was supported by grants from the National Institute of Health. [Extracted from the article]

A recent study from Harvard Medical School explores the multifaceted roles of leptin receptor positive bone marrow mesenchymal stromal cells (MSCs) in hematopoiesis, osteogenesis, and bone marrow adipogenesis. These MSCs are non-hematopoietic stromal cells found in the bone marrow microenvironment that provide niche factors for hematopoietic stem cells (HSCs). The study discusses the different subtypes of leptin receptor positive MSCs and their impact on HSC maintenance, tissue regeneration, metabolic disorders, and immune responses. The research holds promise for advancing our understanding of HSC biology and various related processes. [Extracted from the article]

A study conducted by researchers at the University of Cincinnati explores the effect of a genetic variant in the leptin receptor on the production of the proinflammatory cytokine macrophage migration inhibitory factor (MIF) in patients with Clostridioides difficile infection (CDI). The researchers found that individuals who express the mutant/derived leptin receptor have higher levels of plasma MIF early after exposure to C. difficile. This suggests that targeting MIF, potentially in combination with the leptin receptor genotype, could be a therapeutic approach for CDI. The study was supported by the National Institutes of Health, the US Department of Veterans Affairs, and the University of Cincinnati College of Medicine. [Extracted from the article]

A recent report from Ohio State University discusses the use of prime editing to correct a mutation in the leptin receptor gene in muscle cells of db/db mice. Prime editing is a genomic editing technique that does not require double-strand breaks or donor DNA templates. The study demonstrated that prime editing successfully corrected the mutation and resulted in enhanced leptin receptor signals in the treated muscle cells. This research offers potential advancements in the treatment of monogenic genetic diseases. [Extracted from the article]

Researchers from Slovak University of Agriculture in Nitra conducted a study to analyze genetic polymorphisms in genes encoding leptin receptor (LEPR) and ghrelin (GHR) as genetic markers of metabolic disorders in human nutrition. They obtained genomic DNA from 84 human blood samples and used the PCR-RFLP method to identify SNPs in the LEPR and GHR genes. The study found a significant association between the genetic markers and levels of LDL cholesterol, suggesting that these genes may be involved in lipid metabolism disorders and obesity. Further research is needed to explore the role of these genes in nutritional status. [Extracted from the article]

A recent study conducted by researchers at the National Institute of Biological Sciences in Beijing, China, has found that nerve growth factor (NGF) produced by leptin receptor-expressing stromal cells is crucial for maintaining nerve fibers in adult bone marrow. The study discovered that nerves promote bone marrow regeneration by activating adrenergic receptor signaling in these cells, leading to increased production of growth factors. This reciprocal relationship between nerves and leptin receptor-expressing cells plays a vital role in the regeneration of bone marrow. The research was supported by various organizations and has been peer-reviewed. [Extracted from the article]

Researchers at Regeneron Pharmaceuticals Inc. have conducted a phase I study on mibavademab, a monoclonal antibody being investigated for the treatment of conditions associated with leptin deficiency. The study involved healthy participants who received single-ascending doses or multiple doses of mibavademab. The researchers found that mibavademab pharmacokinetics were nonlinear with target-mediated elimination, and there were no dose-dependent differences in total soluble leptin receptor levels. They also observed that participants with lower baseline leptin levels had lower mean mibavademab concentrations, higher mean total soluble leptin receptor concentrations, and larger decreases in body weight. The study concluded that mibavademab shows promise for the treatment of conditions associated with leptin deficiency. [Extracted from the article]

A recent study conducted by researchers at Universita degli Studi di Milano in Italy explored the role of leptin, an appetite-regulating hormone, in anorexia nervosa (AN). The study used a rat model of anorexia and found that leptin levels were reduced in adolescent female rats with anorexia. The researchers also observed changes in the leptin signaling pathway in the hippocampus, a brain region involved in spatial memory and emotion regulation. These findings provide new insights into the mechanisms underlying anorexia and may contribute to a better understanding of the disorder. [Extracted from the article]

A recent study conducted by the Shanghai Engineering Research Center of Tooth Restoration and Regeneration has shed light on the impaired bone healing in tooth extraction sockets caused by periodontitis. The researchers found that leptin receptor (LepR) expressing stromal cells, which are involved in bone formation, are inhibited by the CCRL2 receptor in alveolar bones affected by periodontitis. This inhibition hinders the osteogenic differentiation of LepR+ cells and leads to poor bone healing. The study provides new insights into the mechanisms behind periodontitis and its impact on bone repair. [Extracted from the article]

A recent study conducted by the Institute of Brain Research in Taipei, Taiwan, has found that interleukin-4 (IL-4) plays a significant role in regulating appetite control in mice with leptin dysfunction. The researchers discovered that IL-4 reduces body weight, food intake, and serum glucose levels. It also affects the expression of various neuropeptides involved in appetite regulation and reduces hypothalamic inflammation. These findings suggest that targeting IL-4 could be a potential therapeutic approach for obesity and related metabolic disorders. The study has been peer-reviewed and provides valuable insights into the role of IL-4 in mediating food-intake behaviors and metabolic efficiency. [Extracted from the article]

Researchers from the Slovak University of Agriculture conducted a study to identify gene polymorphisms in the Leptin and Ghrelin receptors in the human population. Leptin is a hormone that plays a role in energy metabolism and body weight, while Ghrelin is a hormone produced by the stomach that stimulates growth hormone secretion and enhances feeding and weight gain. The study included 35 human samples, and the researchers used specific restriction enzymes to analyze the gene polymorphisms. The researchers concluded that the identified gene mutation may be connected to human obesity levels. For more information, readers can refer to the article "Association Analysis of the Leptin and Ghrelin Receptor Gene Polymorphism in the Human with BMI" published in Scientific Papers Animal Science and Biotechnologies. [Extracted from the article]

A recent study conducted by the University of Otago in Dunedin, New Zealand, examined the effects of age on the satiety effects of leptin in male mice. Leptin is a hormone that regulates food intake and body weight. The researchers found that while leptin administration reduced food intake in young mice, it had no effect on middle-aged mice. However, in aged mice, leptin administration led to the greatest inhibition of food intake. These findings suggest that there are age-specific changes in the satiety effects of leptin in male mice, highlighting the importance of considering age in metabolic studies. [Extracted from the article]

A study conducted by researchers at the Kyrgyz State Medical Academy in Bishkek, Kyrgyzstan, aimed to investigate the association between a specific genetic polymorphism (Gln223Arg) of the leptin receptor gene and metabolic syndrome components in the Kyrgyz population. The study involved 237 Kyrgyz subjects aged 35-70 years, and various measurements such as anthropometric data, glucose, insulin, lipid spectrum, and leptin levels were obtained. The results showed that the Gln223Arg polymorphism was associated with a higher risk of insulin resistance and higher levels of glycemia and insulinemia. However, no association was found with abdominal obesity, arterial hypertension, hypertriglyceridemia, or low-density cholesterol levels. The researchers concluded that further studies are needed to confirm these results in populations from other regions. [Extracted from the article]

A study conducted at the University of Oxford in the United Kingdom has found that a population of cells called immunomodulatory leptin receptor-positive (LepR+) sympathetic perineurial barrier cells (SPCs) play a role in protecting against obesity. These cells are present in both mice and humans and are involved in regulating brown adipose tissue (BAT) thermogenesis. The researchers discovered that mice lacking IL33 in SPCs had increased inflammation in BAT and were more susceptible to diet-induced obesity. This study highlights the connection between leptin, immune regulation, and body weight, bridging the gap between neuroendocrinology and immunometabolism in obesity research. [Extracted from the article]

A recent study conducted by researchers at the National and Kapodistrian University of Athens explores the relationship between CART and leptin gene expressions, reproductive hormones, and obesity in women who have undergone bariatric surgery. The study found that after surgery, there was a significant reduction in BMI and notable hormonal changes. High expressions of CART and leptin before treatment were correlated with lower expressions after treatment. These findings provide insights into personalized treatment strategies for obesity-related infertility and contribute to a deeper understanding of this complex medical issue. [Extracted from the article]

A recent study conducted by researchers at the Oswaldo Cruz Foundation (FIOCRUZ) in Rio de Janeiro, Brazil, explored the influence of chronic social stress on individuals and the role of leptin and its receptors in this process. The study found that chronic social stress can lead to neuroendocrine disorders and behavioral changes, such as aggressiveness. The researchers evaluated the distribution of leptin and its receptors in the brains of mice subjected to chronic social stress and found that different behavioral categories of mice showed variations in leptin concentration and receptor expression in specific brain regions. The study suggests that leptin and its receptors play a role in how individuals react to stressful situations. [Extracted from the article]

A recent preprint abstract discusses the role of leptin, an adipose tissue hormone, in regulating food intake. Leptin inhibits orexigenic agouti-related protein (AGRP) neurons and activates anorexigenic pro-opiomelanocortin (POMC) neurons to regulate appetite and metabolism. The abstract reports the discovery of a new population of leptin-target neurons expressing basonuclin 2 (Bnc2) that acutely suppress appetite by directly inhibiting AGRP neurons. These BNC2-expressing neurons play a key role in the neural circuit that maintains energy balance. However, it is important to note that this preprint has not yet undergone peer review. [Extracted from the article]

Regeneron Pharmaceuticals Inc. has been issued a patent for bispecific antigen binding molecules that bind to the leptin receptor and/or GP130. These molecules have the potential to activate both receptors and stimulate the anorexigenic effects associated with signaling through these receptors. The patent describes the use of bispecific antibodies to target cells expressing the leptin receptor and/or GP130, which could be beneficial in treating conditions such as obesity and diseases caused by leptin deficiency or resistance. The patent provides detailed information on the structure and composition of these bispecific antigen-binding molecules. [Extracted from the article]

A report from Universidad San Sebastian in Santiago, Chile discusses the interplay between leptin, glucocorticoids, and GLP1 in regulating food intake and feeding behavior. The research explores how these hormone systems interact at both the central and peripheral levels to control energy balance and metabolic homeostasis. The study also examines the role of these systems in dysregulated intake, including obesity and eating behavior disorders. The research has been peer-reviewed and provides valuable insights into the neuroendocrine mechanisms involved in food intake regulation. [Extracted from the article]

A recent study conducted by Regeneron Pharmaceuticals Inc. has explored the use of a monoclonal antibody called REGN4461 as a potential treatment for lipodystrophy, a condition characterized by the loss of fat tissue. The study found that REGN4461 was able to normalize body weight, food intake, blood glucose, and insulin sensitivity in obese mice lacking the hormone leptin. In addition, the antibody alleviated various symptoms associated with lipodystrophy in a mouse model. The researchers also reported positive results from a phase 1 clinical trial and compassionate-use treatment of a patient with lipodystrophy. These findings suggest that REGN4461 may be a promising therapeutic option for individuals with low leptin concentrations. [Extracted from the article]

A recent report discusses research on bladder cancer, which is one of the ten most common tumors globally. The study focused on the association between obesity and bladder cancer risk, specifically examining the levels of leptin and its receptor in patients. The research found that bladder cancer patients had higher levels of leptin and lower levels of the leptin receptor. Additionally, certain genetic variants in the LEPR gene were associated with bladder cancer. The findings suggest that lifestyle changes and disturbances in energy metabolism may play a role in the development of bladder cancer. [Extracted from the article]

ConclusionIn PAH, increased circulating leptin can influence metabolic signaling in RV cardiomyocytes via the leptin receptor; in particular, it may alter lipid-dependent RV metabolism in combination with metformin in a mutation-specific manner and warrants further investigation." Keywords: Adipokines; Biguanides; Cardiology; Cardiomyocyte; Cardiovascular Diseases and Conditions; Genetics; Health and Medicine; Hypertension; Intercellular Signaling Peptides and Proteins; Leptin; Metformin EN Adipokines Biguanides Cardiology Cardiomyocyte Cardiovascular Diseases and Conditions Genetics Health and Medicine Hypertension Intercellular Signaling Peptides and Proteins Leptin Metformin 193 193 1 10/24/23 20231023 NES 231023 2023 OCT 23 (NewsRx) -- By a News Reporter-Staff News Editor at Cardiovascular Week -- Investigators discuss new findings in hypertension. [Extracted from the article]

Our news editors obtained a quote from the research from Islamic Azad University: "To recognise LEP G2548A and LEP receptor Q223R polymorphisms in Iranian people and their association with type 1 diabetes susceptibility. Keywords: Adipokines; Genetics; Health and Medicine; Insulin Dependent Diabetes Mellitus; Intercellular Signaling Peptides and Proteins; Leptin; Nutritional and Metabolic Diseases and Conditions; Type 1 Diabetes EN Adipokines Genetics Health and Medicine Insulin Dependent Diabetes Mellitus Intercellular Signaling Peptides and Proteins Leptin Nutritional and Metabolic Diseases and Conditions Type 1 Diabetes 118 118 1 10/03/23 20231003 NES 231003 2023 OCT 2 (NewsRx) -- By a News Reporter-Staff News Editor at Diabetes Week -- Investigators discuss new findings in type 1 diabetes. [Extracted from the article]

For more information on this research see: Congenital leptin receptor deficiency: A novel leptin receptor gene mutation in an Indian family producing severe early-onset monogenic obesity. Keywords: Adipokine Receptors; Adipokines; Bariatrics; Diet and Nutrition; Genetics; Health and Medicine; Intercellular Signaling Peptides and Proteins; Leptin; Leptin Receptors; Membrane Proteins; Nutrition Disorders; Nutritional and Metabolic Diseases and Conditions; Obesity; Overnutrition EN Adipokine Receptors Adipokines Bariatrics Diet and Nutrition Genetics Health and Medicine Intercellular Signaling Peptides and Proteins Leptin Leptin Receptors Membrane Proteins Nutrition Disorders Nutritional and Metabolic Diseases and Conditions Obesity Overnutrition 1399 1399 1 09/25/23 20230925 NES 230925 2023 SEP 29 (NewsRx) -- By a News Reporter-Staff News Editor at Obesity, Fitness & Wellness Week -- Current study results on obesity have been published. [Extracted from the article]

Keywords for this news article include: London, Europe, Leptin, Adipokines, Pediatrics, United Kingdom, Intercellular Signaling Peptides and Proteins. Keywords: London; United Kingdom; Europe; Adipokines; Intercellular Signaling Peptides and Proteins; Leptin; Pediatrics EN London United Kingdom Europe Adipokines Intercellular Signaling Peptides and Proteins Leptin Pediatrics 220 220 1 09/19/23 20230922 NES 230922 2023 SEP 23 (NewsRx) -- By a News Reporter-Staff News Editor at Pediatrics Week -- New research on Intercellular Signaling Peptides and Proteins - Adipokines is the subject of a report. London, United Kingdom, Europe, Adipokines, Intercellular Signaling Peptides and Proteins, Leptin, Pediatrics. [Extracted from the article]

Our news editors obtained a quote from the research from Yantai University: "The mainstays of clinical management for this disease are surgery, targeted drugs therapy, and no-targeted drugs drug therapy. targeted drugs can improve therapeutic efficacy and enhance the quality of life for GO patients. According to the news editors, the research concluded: "A deeper understanding of the pathogenesis of GO and the role of potential target signaling pathways is crucial for effective treatment of this disease." According to news reporting out of Shandong, People's Republic of China, by NewsRx editors, research stated, "Graves' orbitopathy (GO) is an autoimmune disease that involves complex immune systems.". [Extracted from the article]

Keywords: Adipokines; Brain; Central Nervous System; Diencephalon; Health and Medicine; Hypothalamus; Intercellular Signaling Peptides and Proteins; Leptin; Limbic System EN Adipokines Brain Central Nervous System Diencephalon Health and Medicine Hypothalamus Intercellular Signaling Peptides and Proteins Leptin Limbic System 5838 5838 1 09/11/23 20230915 NES 230915 2023 SEP 15 (NewsRx) -- By a News Reporter-Staff News Editor at Health & Medicine Week -- Research findings on adipokines are discussed in a new report. Using single-nucleus RNA sequencing during scheduled feeding, we identified a dorsomedial hypothalamus leptin receptor-expressing (DMH SP LepR sp ) neuron population that up-regulates circadian entrainment genes and exhibits calcium activity before an anticipated meal. [Extracted from the article]

Piscataway, State:New Jersey, United States, North and Central America, Adipokine Receptors, Adipokines, Diabetes Complications, Diabetes Mellitus, Diabetic Nephropathy, Genetics, Health and Medicine, Intercellular Signaling Peptides and Proteins, Kidney Diseases and Conditions, Leptin, Leptin Receptors, Membrane Proteins, Nephrology, Nephropathy, Nutritional and Metabolic Diseases and Conditions Keywords: Piscataway; State:New Jersey; United States; North and Central America; Adipokine Receptors; Adipokines; Diabetes Complications; Diabetes Mellitus; Diabetic Nephropathy; Genetics; Health and Medicine; Intercellular Signaling Peptides and Proteins; Kidney Diseases and Conditions; Leptin; Leptin Receptors; Membrane Proteins; Nephrology; Nephropathy; Nutritional and Metabolic Diseases and Conditions EN Piscataway State:New Jersey United States North and Central America Adipokine Receptors Adipokines Diabetes Complications Diabetes Mellitus Diabetic Nephropathy Genetics Health and Medicine Intercellular Signaling Peptides and Proteins Kidney Diseases and Conditions Leptin Leptin Receptors Membrane Proteins Nephrology Nephropathy Nutritional and Metabolic Diseases and Conditions 167 167 1 08/21/23 20230821 NES 230821 2023 AUG 21 (NewsRx) -- By a News Reporter-Staff News Editor at Diabetes Week -- New research on Kidney Diseases and Conditions - Diabetic Nephropathy is the subject of a report. [Extracted from the article]

Our news correspondents obtained a quote from the research from Capital Medical University: "Moreover, the role of leptin/leptin receptors axis in obesity and the prognosis of CP is still unknown. Keywords: Adipokines; Bariatrics; Craniopharyngiomas; Diet and Nutrition; Genetics; Health and Medicine; Intercellular Signaling Peptides and Proteins; Leptin; Nutrition Disorders; Nutritional and Metabolic Diseases and Conditions; Obesity; Overnutrition; Risk and Prevention EN Adipokines Bariatrics Craniopharyngiomas Diet and Nutrition Genetics Health and Medicine Intercellular Signaling Peptides and Proteins Leptin Nutrition Disorders Nutritional and Metabolic Diseases and Conditions Obesity Overnutrition Risk and Prevention 186 186 1 07/24/23 20230728 NES 230728 2023 JUL 28 (NewsRx) -- By a News Reporter-Staff News Editor at Obesity, Fitness & Wellness Week -- Data detailed on obesity have been presented. [Extracted from the article]

Acrylamide, Adipokines, Amides, Ghrelin, Intercellular Signaling Peptides and Proteins, Leptin, Peptide Hormones, Peptide Proteins Keywords: Acrylamide; Adipokines; Amides; Ghrelin; Intercellular Signaling Peptides and Proteins; Leptin; Peptide Hormones; Peptide Proteins EN Acrylamide Adipokines Amides Ghrelin Intercellular Signaling Peptides and Proteins Leptin Peptide Hormones Peptide Proteins 6564 6564 1 07/10/23 20230714 NES 230714 2023 JUL 14 (NewsRx) -- By a News Reporter-Staff News Editor at Health & Medicine Week -- A new study on peptide hormones is now available. [Extracted from the article]

Providence, State:Rhode Island, United States, North and Central America, Adipokine Receptors, Genetics, Intercellular Signaling Peptides and Proteins, Leptin, Leptin Receptors, Membrane Proteins, Adipokines Keywords: Providence; State:Rhode Island; United States; North and Central America; Adipokine Receptors; Adipokines; Genetics; Intercellular Signaling Peptides and Proteins; Leptin; Leptin Receptors; Membrane Proteins EN Providence State:Rhode Island United States North and Central America Adipokine Receptors Adipokines Genetics Intercellular Signaling Peptides and Proteins Leptin Leptin Receptors Membrane Proteins 1819 1819 1 07/03/23 20230707 NES 230707 2023 JUL 7 (NewsRx) -- By a News Reporter-Staff News Editor at Genomics & Genetics Weekly -- Current study results on Membrane Proteins - Adipokine Receptors have been published. [Extracted from the article]

In this study, we used pseudorabies virus (PRV) to identify iBAT-related neurons in the paraventricular nucleus (PVN) of the hypothalamus and test the hypothesis that iBAT-related PVN neurons are modulated by leptin. Keywords: New Orleans; State:Louisiana; United States; North and Central America; Adipokine Receptors; Adipokines; Brain; Cells; Central Nervous System; Diencephalon; Health and Medicine; Hypothalamus; Intercellular Signaling Peptides and Proteins; Leptin; Leptin Receptors; Limbic System; Membrane Proteins; Neurons EN New Orleans State:Louisiana United States North and Central America Adipokine Receptors Adipokines Brain Cells Central Nervous System Diencephalon Health and Medicine Hypothalamus Intercellular Signaling Peptides and Proteins Leptin Leptin Receptors Limbic System Membrane Proteins Neurons 2286 2286 1 06/19/23 20230623 NES 230623 2023 JUN 23 (NewsRx) -- By a News Reporter-Staff News Editor at Health & Medicine Week -- Investigators publish new report on Membrane Proteins - Adipokine Receptors. [Extracted from the article]

Valladolid, Spain, Europe, Adipokine Receptors, Adipokines, Abdominal Obesity, Bariatrics, Diet and Nutrition, Diseases and Conditions, Genetics, Health and Medicine, Healthcare, Intercellular Signaling Peptides and Proteins, Leptin, Leptin Receptors, Membrane Proteins, Metabolic Syndrome, Nutrition Disorders, Nutritional and Metabolic Diseases and Conditions, Obesity, Overnutrition, Peptide Hormones, Peptide Proteins, Proinsulin, Risk and Prevention Keywords: Valladolid; Spain; Europe; Abdominal Obesity; Adipokine Receptors; Adipokines; Bariatrics; Diet and Nutrition; Diseases and Conditions; Genetics; Health and Medicine; Healthcare; Intercellular Signaling Peptides and Proteins; Leptin; Leptin Receptors; Membrane Proteins; Metabolic Syndrome; Nutrition Disorders; Nutritional and Metabolic Diseases and Conditions; Obesity; Overnutrition; Peptide Hormones; Peptide Proteins; Proinsulin; Risk and Prevention EN Valladolid Spain Europe Abdominal Obesity Adipokine Receptors Adipokines Bariatrics Diet and Nutrition Diseases and Conditions Genetics Health and Medicine Healthcare Intercellular Signaling Peptides and Proteins Leptin Leptin Receptors Membrane Proteins Metabolic Syndrome Nutrition Disorders Nutritional and Metabolic Diseases and Conditions Obesity Overnutrition Peptide Hormones Peptide Proteins Proinsulin Risk and Prevention 271 271 1 06/19/23 20230623 NES 230623 2023 JUN 23 (NewsRx) -- By a News Reporter-Staff News Editor at Obesity, Fitness & Wellness Week -- Data detailed on Nutritional and Metabolic Diseases and Conditions - Abdominal Obesity have been presented. [Extracted from the article]