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Your search keyword '"Hudis, Clifford"' showing total 2 results
Start Over Author "Hudis, Clifford" Topic cancer relapse Publisher new england journal of medicine
2 results on '"Hudis, Clifford"'

1. Increasing Precision in Adjuvant Therapy for Breast Cancer.

Author

Hudis, Clifford A. and Dickler, Maura

Subjects
*ANTINEOPLASTIC agents, *TAMOXIFEN, *BREAST tumors, *CANCER relapse, *COMBINED modality therapy
Abstract

The article reflects on the MINDACT trial which examined whether the 70-gene signature would reduce the use of adjuvant chemotherapy for breast cancer. It states that a high bar or a randomized design for the trial would be required to convince clinicians and patients that chemotherapy is not needed in healthy younger patients. It concludes that a team of well-coordinated and highly collaborative team of investigators can efficiently carry out a potentially practice-changing study.

Published
2016
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2. Adjuvant Paclitaxel and Trastuzumab for Node-Negative, HER2-Positive Breast Cancer.

Author

Tolaney, Sara M., Barry, William T., Dang, Chau T., Yardley, Denise A., Moy, Beverly, Marcom, P. Kelly, Albain, Kathy S., Rugo, Hope S., Ellis, Matthew, Shapira, Iuliana, Wolff, Antonio C., Carey, Lisa A., Overmoyer, Beth A., Partridge, Ann H., Hao Guo, Hudis, Clifford A., Krop, Ian E., Burstein, Harold J., and Winer, Eric P.

Subjects
*BREAST cancer treatment, *PACLITAXEL, *TRASTUZUMAB, *ADJUVANT treatment of cancer, *HER2 protein, *CANCER relapse, *DRUG side effects, *DRUG efficacy
Abstract

The article discusses a study which examined the treatment of human epidermal growth factor receptor type 2 (HER2)-positive breast cancer using adjuvant paclitaxel and trastuzumab. Topics discussed include the risk of early cancer recurrence, effectiveness and adverse events associated with the adjuvant therapy, and the rate of survival free from the disease.

Published
2015
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