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3. AKT-mTORC1 reactivation is the dominant resistance driver for PI3Kβ/AKT inhibitors in PTEN-null breast cancer and can be overcome by combining with Mcl-1 inhibitors

5. Prioritization of cancer therapeutic targets using CRISPR–Cas9 screens

7. Agreement between two large pan-cancer CRISPR-Cas9 gene dependency data sets

8. Functional linkage of gene fusions to cancer cell fitness assessed by pharmacological and CRISPR-Cas9 screening

9. ATM orchestrates the DNA-damage response to counter toxic non-homologous end-joining at broken replication forks

10. SRPK1 maintains acute myeloid leukemia through effects on isoform usage of epigenetic regulators including BRD4

12. Targeted gene correction of α1-antitrypsin deficiency in induced pluripotent stem cells

13. Low rates of mutation in clinical grade human pluripotent stem cells under different culture conditions

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