1. Re-examining chemically defined liquid diets through the lens of the microbiome.
- Author
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Toni T, Alverdy J, and Gershuni V
- Subjects
- Critical Care methods, Critical Illness therapy, Diet adverse effects, Diet methods, Dietary Fiber microbiology, Dietary Fiber therapeutic use, Food, Formulated adverse effects, History, 20th Century, Humans, Malnutrition diet therapy, Malnutrition history, Malnutrition microbiology, Nutritional Support methods, Parenteral Nutrition, Total adverse effects, Parenteral Nutrition, Total history, Parenteral Nutrition, Total methods, Perioperative Care adverse effects, Perioperative Care methods, United States, Critical Care history, Diet history, Food, Formulated history, Gastrointestinal Microbiome, Nutritional Support history, Perioperative Care history
- Abstract
Trends in nutritional science are rapidly shifting as information regarding the value of eating unprocessed foods and its salutary effect on the human microbiome emerge. Unravelling the evolution and ecology by which humans have harboured a microbiome that participates in every facet of health and disease is daunting. Most strikingly, the host habitat has sought out naturally occurring foodstuff that can fulfil its own metabolic needs and also the needs of its microbiota, each of which remain inexorably connected to one another. With the introduction of modern medicine and complexities of critical care, came the assumption that the best way to feed a critically ill patient is by delivering fibre-free chemically defined sterile liquid foods (that is, total enteral nutrition). In this Perspective, we uncover the potential flaws in this assumption and discuss how emerging technology in microbiome sciences might inform the best method of feeding malnourished and critically ill patients., (© 2021. Springer Nature Limited.)
- Published
- 2021
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