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Your search keyword '"Xueshu Tao"' showing total 2 results
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2 results on '"Xueshu Tao"'

1. STING suppresses bone cancer pain via immune and neuronal modulation

Author

Kaiyuan Wang, Christopher R. Donnelly, Changyu Jiang, Yihan Liao, Xin Luo, Xueshu Tao, Sangsu Bang, Aidan McGinnis, Michael Lee, Matthew J. Hilton, and Ru-Rong Ji

Subjects
Science
Abstract

There is an unmet clinical need to develop therapies to alleviate metastatic bone pain, frequently observed in patients with advanced cancers. Here, using mouse models of bone cancer pain, the authors show that STING agonists not only suppress bone cancer tumor burden, but also attenuate bone pain and reduce cancer-induced bone destruction.

Published
2021
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2. Activation of GPR37 in macrophages confers protection against infection-induced sepsis and pain-like behaviour in mice

Author

Sangsu Bang, Christopher R. Donnelly, Xin Luo, Maria Toro-Moreno, Xueshu Tao, Zilong Wang, Sharat Chandra, Andrey V. Bortsov, Emily R. Derbyshire, and Ru-Rong Ji

Subjects
Science
Abstract

GPR37 is expressed in macrophages, and has been implicated in resolution of inflammatory pain. Here the authors show that GPR37 can modulate sepsis in several animal models.

Published
2021
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