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1. Specificity of the Hox member Deformed is determined by transcription factor levels and binding site affinities

Author

Pedro B. Pinto, Katrin Domsch, Xuefan Gao, Michaela Wölk, Julie Carnesecchi, and Ingrid Lohmann

Subjects
Science
Abstract

Despite the central role of Hox genes in controlling morphogenesis, the DNA binding of different Hox members is relatively similar. Here they show that specificity of Hox member Dfd relies on a precise balance of transcription factors and binding site affinities.

Published
2022
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