Search

Your search keyword '"Vanessa Delcroix"' showing total 1 results
Start Over Author "Vanessa Delcroix" Publisher nature portfolio
1 results on '"Vanessa Delcroix"'

1. mTORC1 inhibition in cancer cells protects from glutaminolysis-mediated apoptosis during nutrient limitation

Author

Victor H. Villar, Tra Ly Nguyen, Vanessa Delcroix, Silvia Terés, Marion Bouchecareilh, Bénédicte Salin, Clément Bodineau, Pierre Vacher, Muriel Priault, Pierre Soubeyran, and Raúl V. Durán

Subjects
Science
Abstract

Inhibitors of the mTORC1 pathway are considered anti-cancer drugs. Here, the authors show that on nutrient restriction, glutaminolysis-induced activation of mTORC1 induces apoptosis via inhibiting autophagy, highlighting that under such conditions inhibition of mTORC1 results in survival of cancer cells.

Published
2017
Full Text
View/download PDF

Catalog

Books, media, physical & digital resources
See catalog results