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1. The enzymatic activity of inositol hexakisphosphate kinase controls circulating phosphate in mammals

Author

Yusuke Moritoh, Shin-ichi Abe, Hiroki Akiyama, Akihiro Kobayashi, Ryokichi Koyama, Ryoma Hara, Shizuo Kasai, and Masanori Watanabe

Subjects
Science
Abstract

Inositol hexakisphosphate kinase (IP6K) is involved in diverse cellular signalling pathways, but the physiological roles of IP6K in vivo remain unknown in mammals. Here, the authors show that the enzymatic activity of IP6K is essential for phosphate regulation in vivo.

Published
2021
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