Search

Your search keyword '"Shaoyu Zhong"' showing total 2 results
Start Over Author "Shaoyu Zhong" Publisher nature portfolio
2 results on '"Shaoyu Zhong"'

1. Hepatocyte phosphatase DUSP22 mitigates NASH-HCC progression by targeting FAK

Author

Chenxu Ge, Jun Tan, Xianling Dai, Qin Kuang, Shaoyu Zhong, Lili Lai, Chao Yi, Yan Sun, Jing Luo, Chufeng Zhang, Liancai Zhu, Bochu Wang, and Minxuan Xu

Subjects
Science
Abstract

Mechanisms underlying the pathogenesis of nonalcoholic steatohepatitis are unclear. Here, the authors show that ROS-mediated DUSP22 degradation participates in the progression of fatty liver, contributing to the development of NASH and associated HCC via regulating FAK and its downstream ERK1/2 and NF-κB signaling cascade.

Published
2022
Full Text
View/download PDF

2. The E3 ubiquitin-protein ligase Trim31 alleviates non-alcoholic fatty liver disease by targeting Rhbdf2 in mouse hepatocytes

Author

Minxuan Xu, Jun Tan, Wei Dong, Benkui Zou, Xuepeng Teng, Liancai Zhu, Chenxu Ge, Xianling Dai, Qin Kuang, Shaoyu Zhong, Lili Lai, Chao Yi, Tingting Tang, Junjie Zhao, Longyan Wang, Jin Liu, Hao Wei, Yan Sun, Qiufeng Yang, Qiang Li, Deshuai Lou, Linfeng Hu, Xi Liu, Gang Kuang, Jing Luo, Mingxin Xiong, Jing Feng, Chufeng Zhang, and Bochu Wang

Subjects
Science
Abstract

Nonalcoholic steatohepatitis (NASH) is a chronic liver disease with complex disease mechanisms. Here the authors report that the E3 ubiquitin-protein ligase Trim31 mitigates development of NASH via inhibition of rhomboid 5 homolog 2 (Rhbdf2) in mice.

Published
2022
Full Text
View/download PDF

Catalog

Books, media, physical & digital resources
See catalog results