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1. Inter-individual variability amplified through breeding reveals control of reward-related action strategies by Melanocortin-4 Receptor in the dorsomedial striatum

Author

Aylet T. Allen, Elizabeth C. Heaton, Lauren P. Shapiro, Laura M. Butkovich, Sophie T. Yount, Rachel A. Davies, Dan C. Li, Andrew M. Swanson, and Shannon L. Gourley

Subjects
Biology (General), QH301-705.5
Abstract

To uncover mechanisms underlying reward-seeking behaviours, Allen et al. employ a task in which mice must arbitrate between rewarded and nonrewarded behaviors. They demonstrate that individual differences in response flexibility are associated with melanocortin-4 receptor density in the dorsomedial striatum.

Published
2022
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