Search

Your search keyword '"Boris A. Kashemirov"' showing total 2 results
Start Over Author "Boris A. Kashemirov" Publisher nature portfolio
2 results on '"Boris A. Kashemirov"'

1. Fluorescent risedronate analogue 800CW-pRIS improves tooth extraction-associated abnormal wound healing in zoledronate-treated mice

Author

Hiroko Okawa, Takeru Kondo, Akishige Hokugo, Philip Cherian, Oskar Sundberg, Jesus J. Campagna, Boris A. Kashemirov, Varghese John, Shuting Sun, Frank H. Ebetino, Charles E. McKenna, and Ichiro Nishimura

Subjects
Medicine
Abstract

Okawa et al. evaluate a fluorescent risedronate analogue, 800CW-pRIS, as a potential treatment for medication-related osteonecrosis of the jaw. The authors demonstrate an improvement in wound healing and inflammation with 800CW-pRIS pre-treatment in a mouse model of bisphosphonate-associated osteonecrosis following tooth extraction.

Published
2022
Full Text
View/download PDF

2. Selective BET bromodomain inhibition as an antifungal therapeutic strategy

Author

Flore Mietton, Elena Ferri, Morgane Champleboux, Ninon Zala, Danièle Maubon, Yingsheng Zhou, Mike Harbut, Didier Spittler, Cécile Garnaud, Marie Courçon, Murielle Chauvel, Christophe d’Enfert, Boris A. Kashemirov, Mitchell Hull, Muriel Cornet, Charles E. McKenna, Jérôme Govin, and Carlo Petosa

Subjects
Science
Abstract

BET proteins bind chromatin through their bromodomains (BDs) to regulate transcription and chromatin remodelling. Here, the authors show that the BET protein Bdf1 is essential for the fungal pathogenCandida albicans, and report compounds that inhibit the Bdf1 BDs with high selectivity over human BDs.

Published
2017
Full Text
View/download PDF

Catalog

Books, media, physical & digital resources
See catalog results