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Your search keyword '"clade 2.3.4"' showing total 2 results
Start Over Descriptor "clade 2.3.4" Publisher national center for infectious diseases, centers for disease control and prevention (cdc)
2 results on '"clade 2.3.4"'

1. Rapid Emergence of Highly Pathogenic Avian Influenza Subtypes from a Subtype H5N1 Hemagglutinin Variant.

Author

de Vries E, Guo H, Dai M, Rottier PJ, van Kuppeveld FJ, and de Haan CA

Subjects
Animals, Disease Outbreaks, Genotype, Humans, Influenza A Virus, H5N1 Subtype pathogenicity, Influenza A virus pathogenicity, Phylogeny, Poultry, Reassortant Viruses classification, Reassortant Viruses genetics, Genetic Variation, Hemagglutinins genetics, Influenza A Virus, H5N1 Subtype genetics, Influenza A virus classification, Influenza A virus genetics, Influenza in Birds virology, Influenza, Human virology
Abstract

In 2014, novel highly pathogenic avian influenza A H5N2, H5N5, H5N6, and H5N8 viruses caused outbreaks in Asia, Europe, and North America. The H5 genes of these viruses form a monophyletic group that evolved from a clade 2.3.4 H5N1 variant. This rapid emergence of new H5Nx combinations is unprecedented in the H5N1 evolutionary history.

Published
2015
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2. Novel variants of clade 2.3.4 highly pathogenic avian influenza A(H5N1) viruses, China.

Author

Gu M, Zhao G, Zhao K, Zhong L, Huang J, Wan H, Wang X, Liu W, Liu H, Peng D, and Liu X

Subjects
Animals, Chickens, China epidemiology, Hemagglutinin Glycoproteins, Influenza Virus genetics, Phylogeny, Poultry virology, Poultry Diseases epidemiology, Poultry Diseases virology, Genotype, Influenza A Virus, H5N1 Subtype classification, Influenza A Virus, H5N1 Subtype genetics, Influenza in Birds epidemiology, Influenza in Birds virology
Abstract

We characterized 7 highly pathogenic avian influenza A(H5N1) viruses isolated from poultry in China during 2009-2012 and found that they belong to clade 2.3.4 but do not fit within the 3 defined subclades. Antigenic drift in subtype H5N1 variants may reduce the efficacy of vaccines designed to control these viruses in poultry.

Published
2013
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