8 results on '"Brawn, W J"'
Search Results
2. A new syndrome of multiple hemangiomas, right dominant double aortic arch, and coarctation.
- Author
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Wong CH, Wright JG, Silove ED, Willetts R, and Brawn WJ
- Subjects
- Angiography, Aortic Coarctation complications, Aortic Coarctation diagnosis, Cardiac Catheterization, Female, Follow-Up Studies, Hemangioma diagnosis, Humans, Infant, Newborn, Male, Skin Neoplasms diagnosis, Syndrome, Treatment Outcome, Aorta, Thoracic abnormalities, Aorta, Thoracic surgery, Aortic Coarctation surgery, Cardiac Surgical Procedures methods, Hemangioma complications, Skin Neoplasms complications
- Published
- 2001
- Full Text
- View/download PDF
3. The modified Norwood procedure for hypoplastic left heart syndrome: early to intermediate results of 120 patients with particular reference to aortic arch repair.
- Author
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Ishino K, Stümper O, De Giovanni JJ, Silove ED, Wright JG, Sethia B, Brawn WJ, and de Leval M
- Subjects
- Anastomosis, Surgical, Biocompatible Materials, Blood Vessel Prosthesis Implantation mortality, Cardiac Surgical Procedures, Female, Follow-Up Studies, Humans, Hypoplastic Left Heart Syndrome mortality, Infant, Infant, Newborn, Male, Palliative Care methods, Polytetrafluoroethylene, Retrospective Studies, Survival Rate, Treatment Outcome, Aorta, Thoracic surgery, Blood Vessel Prosthesis Implantation methods, Hypoplastic Left Heart Syndrome surgery, Pulmonary Artery surgery
- Abstract
Background: Classic first-stage Norwood repair of hypoplastic left heart syndrome uses a homograft patch enlargement to obtain an unobstructed aorta and coronary arteries. Because of possible disadvantages of the homograft, such as lack of growth, degeneration and calcification, and availability, we have tried to repair the aorta without patch supplementation., Methods: Between February 1993 and September 1997, 120 patients, aged birth to 47 days (median 4 days) and weighing 1.7 to 4.4 kg (median 3.1 kg), underwent first-stage palliation for hypoplastic left heart syndrome. The diameter of the ascending aorta ranged from 1.5 to 8.0 mm (median 3.0 mm). Eight patients had an aberrant right subclavian artery arising from the descending thoracic aorta. In 95 patients (group I), all duct tissue was excised and the descending aorta was anastomosed to the aortic arch, which had been opened back into the ascending aorta. Then to this confluence was anastomosed the proximal main pulmonary artery. In the remaining 25 patients (group II), continuity of the aortic arch was maintained and the repair was performed with a Damus-Kaye-Stansel anastomosis. The size of the systemic-to-pulmonary shunt was 3 mm in 48 patients, 3.5 mm in 70, and 4.0 mm in 2., Results: Circulatory arrest time ranged from 19 to 105 minutes (median 54 minutes). A homograft patch was necessary for the arch reconstruction in 18 patients (15%); 9 group I patients (10%) and 9 group II (36%) (P =.001). There were 82 hospital survivors (68%); 69 group I patients (73%) and 13 group II (52%) (P =.04), 71 patients without a patch (70%) and 11 with a patch (61%) (P >.2). By multiple logistic regression, the aberrant right subclavian artery was a significant risk factor for hospital death (P =.008). There were 6 late deaths. Sixteen of 71 patients (23%) who underwent second-stage palliation had a neoaortic arch obstruction develop, with a peak gradient greater than 10 mm Hg; 14 group I patients (23%) and 2 group II (22%) ( P >.2), 15 without a patch (23%) and 1 with a patch (17%) (P >.2). Overall survivals were 57% at 1 year and 55% at 2 years., Conclusion: The modified Norwood procedure for first-stage palliation of hypoplastic left heart syndrome is possible in the majority of patients without the use of exogenous materials and does not result in an increased incidence of neoaortic arch obstruction. Repair of the aorta without patch supplementation may improve the potential for long-term growth of the new aorta.
- Published
- 1999
- Full Text
- View/download PDF
4. Two-patch repair of complete atrioventricular septal defect in the first year of life. Results and sequential assessment of atrioventricular valve function.
- Author
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Weintraub RG, Brawn WJ, Venables AW, and Mee RB
- Subjects
- Female, Heart Septal Defects mortality, Heart Valve Diseases congenital, Heart Valves physiopathology, Humans, Infant, Infant, Newborn, Male, Postoperative Period, Prostheses and Implants, Reoperation, Heart Septal Defects surgery, Heart Valve Diseases surgery
- Abstract
Before January 1987, 62 infants underwent two-patch repair of complete (51) or intermediate (11) atrioventricular septal defect at the Royal Children's Hospital, Melbourne. Median age at repair was 4.3 months and median weight was 4.4 kg. Early deaths (3%) were confined to two infants with preoperative respiratory tract infections; a further two patients died during follow-up (late mortality rate 3%). Reoperation for severe postoperative mitral regurgitation was necessary in 10 infants (16%), two of whom subsequently required mitral valve replacement with a prosthesis. Preoperative atrioventricular valve regurgitation was assessed retrospectively in 49 patients from angiography or Doppler echocardiography and was found to be absent or mild in 33 (68%), moderate in 9 (18%), and severe in 7 (14%). At the time of latest review (at a mean of 2.4 years after repair), judged from a combination of clinical and echocardiographic criteria, mitral regurgitation was absent or mild in 49 (84%) of the 58 survivors; none of them had symptomatic regurgitation or were requiring continuing medical treatment. Analysis of sequential atrioventricular valve function in 46 of the 49 patients in whom objective preoperative data were available showed no relationship between the degree of preoperative and postoperative atrioventricular valve regurgitation. Infants without Down's syndrome, however, had a significantly higher reoperation rate for severe postoperative mitral valve regurgitation (50%) than those with Down's syndrome (10%) (p = 0.007). Complete atrioventricular septal defect can be repaired in early infancy with a low mortality rate and good intermediate term results.
- Published
- 1990
5. Total anomalous pulmonary venous drainage.
- Author
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Sano S, Brawn WJ, and Mee RB
- Subjects
- Angiography, Arrhythmias, Cardiac etiology, Cardiac Catheterization, Child, Preschool, Echocardiography, Female, Follow-Up Studies, Heart Defects, Congenital diagnosis, Heart Defects, Congenital mortality, Humans, Infant, Infant, Newborn, Male, Postoperative Complications etiology, Pulmonary Veins surgery, Heart Defects, Congenital surgery, Pulmonary Veins abnormalities
- Abstract
Forty-four patients with total anomalous pulmonary venous drainage underwent repair between 1979 and 1987. The anomalous drainage was supracardiac in 16, cardiac in 12, and infracardiac in 16. Median age at repair was 15 days and median weight, 3.3 kg. In 22 patients (50%) the venous drainage was obstructed. Emergency operation was necessary in 12 patients, and the condition of seven additional patients deteriorated while they were awaiting semiurgent operation. There was one hospital death (mortality rate 2.3%), occurring in a 2-week-old premature neonate with infracardiac drainage. In 17 of 44 patients, mean pulmonary artery pressure equaled or exceeded systemic arterial pressure immediately after repair. Four patients have required reoperation and two of these have died as a result of peripheral extension of pulmonary vein sclerosis. In the review period of from 1 month to 7 years, all survivors are well and receiving no medication.
- Published
- 1989
6. Truncus arteriosus. Surgical approach.
- Author
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Sharma AK, Brawn WJ, and Mee RB
- Subjects
- Blood Pressure, Body Weight, Cardiac Output, Low etiology, Cardiopulmonary Bypass, Child, Preschool, Ductus Arteriosus, Patent mortality, Ductus Arteriosus, Patent physiopathology, Humans, Infant, Postoperative Complications, Ductus Arteriosus, Patent surgery
- Abstract
Between mid-1979 and December, 1983, 23 patients with various types of truncus arteriosus underwent total surgical correction at Royal Children's Hospital, Melbourne, Australia. Nineteen patients had primary total repair and four had secondary repair, three having survived banding done prior to 1978. Sixteen patients were less than 1 year of age. Repair was performed with circulatory arrest in infants and cardiopulmonary bypass with core cooling in older patients. Patients were electively ventilated preoperatively. In the postoperative period, pulmonary artery pressure was monitored very closely and any rise was treated with hyperventilation and vasodilators. Two patients under 1 month of age, who were severely acidotic and anuric preoperatively, died of low output syndrome. Among the rest of the infants there was only one death, probably because of pulmonary hypertensive crisis that might have been prevented. From our experience, we think that patients with truncus arteriosus should have total correction during infancy, preferably at 2 to 3 months of age, as it can be performed with a very low risk and also avoids the development of pulmonary vascular disease, which occurs very rapidly in these infants.
- Published
- 1985
7. Early results for anatomic correction of transposition of the great arteries and for double-outlet right ventricle with subpulmonary ventricular septal defect.
- Author
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Brawn WJ and Mee RB
- Subjects
- Aorta pathology, Aorta surgery, Aortic Coarctation surgery, Cardiac Catheterization, Child, Preschool, Coronary Vessels pathology, Coronary Vessels surgery, Double Outlet Right Ventricle mortality, Double Outlet Right Ventricle pathology, Female, Follow-Up Studies, Heart Septal Defects, Ventricular mortality, Heart Septal Defects, Ventricular pathology, Humans, Infant, Infant, Newborn, Male, Postoperative Complications epidemiology, Preoperative Care, Pulmonary Artery abnormalities, Pulmonary Artery surgery, Transposition of Great Vessels mortality, Transposition of Great Vessels pathology, Double Outlet Right Ventricle surgery, Heart Septal Defects, Ventricular surgery, Transposition of Great Vessels surgery
- Abstract
Fifty patients, 21 with transposition of the great arteries plus ventricular septal defect, four with double-outlet right ventricle plus ventricular septal defect, and 25 with transposition of the great arteries plus intact ventricular septum, have undergone anatomic correction. There were four hospital deaths, all in the patients with ventricular septal defects (overall mortality rate 8%). The Lecompte maneuver was used in all patients, and in the last 25 patients the coronary arteries were transposed to medially hinged trapdoor flaps created in the neoaorta. In 10 patients (20%) intraoperative adjustments were necessary to the great vessels and coronary arteries to achieve unobstructed coronary artery flow. There have been no late deaths. Postoperative cardiac catheterization in 19 patients has revealed stenosis on the new main pulmonary artery suture line to be the main early problem. Anatomic correction of transposition (with or without ventricular septal defect) and double-outlet right ventricle septal defect would seem to be a good operative alternative to the Mustard or Senning operation, with the advantage of incorporating the left ventricle into the systemic circulation.
- Published
- 1988
8. Pulmonary atresia with intact ventricular septum.
- Author
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Joshi SV, Brawn WJ, and Mee RB
- Subjects
- Echocardiography, Follow-Up Studies, Heart Septum pathology, Heart Ventricles surgery, Hemodynamics, Humans, Infant, Newborn, Pulmonary Artery surgery, Pulmonary Valve surgery, Reoperation, Retrospective Studies, Subclavian Artery surgery, Tricuspid Valve pathology, Heart Septum surgery, Palliative Care methods, Pulmonary Valve abnormalities
- Abstract
Neonates with pulmonary atresia with intact ventricular septum are ductus dependent from birth. The initial approach in these patients is to ensure continued adequate pulmonary blood flow in anticipation of imminent spontaneous closure of the ductus. Our experience and evolving approach in the management of 16 consecutive neonates with pulmonary atresia with intact ventricular septum from 1978 to 1984 is presented. On the basis of the revised classification by Bull and associates, we divided the patients into four different groups according to right ventricular morphology. Basically, three types of palliative surgical procedures were performed: systemic-pulmonary artery shunt; systemic-pulmonary artery shunt with pulmonary valvotomy; and pulmonary valvotomy alone. Systemic-pulmonary artery shunt is the most important part of neonatal palliation. Our present routine is to perform left subclavian-main pulmonary artery shunt with a polytetrafluoroethylene tube in all patients and, in addition, to perform an open transpulmonary valvotomy without cardiopulmonary bypass in patients with a patent infundibular portion of the right ventricle. Our technique and the advantages of this type of shunt procedure are discussed. Patients with right ventricular sinusoidal-coronary artery communications are a subgroup with an additional problem. In our series, patients with this anomaly are categorized into groups with major and minor connections and their surgical significance is discussed. Overall, there was one death among 16 patients after neonatal palliative procedures and one death among five patients after hemodynamic repair.
- Published
- 1986
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