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Amlapitta or Acid peptic disease i s a common crisis in this present era which impinges on more than 40 % of the population . It can be considered as Prajnaparadha janya vyadhi , as it occurs beca use of undisciplined and imbalanced food habits , where the concept of Hitabhuk , Mitabhuk and Rhutabhuk is totally ignored . S imilarly , with immense degree , hectic routine and psychological stress is also responsible for this condition. In this condition, Vi dagdhata of Pitta with dominancy of Amla bhava is seen . Amlapitta presents with the cardinal features like Avipaka, Klama, Utklesha, Tikta - Amla Udgara, Gaurava, Hrit - Kanta Daha and Aruchi. Depending upon Doshotklesha Gati , Amlapitta is of two types viz Urd hvaga Amlapitta and Adhoga Amlapitta. The line of treatment f or this condition includes Shodhana and Shamana. A clinical study was conducted with Sad y o Vamana followed by the internal administration of Yavakshara. Sady o Vamana helps to evacuate the Utklist a Dosha from Amashaya. Kshara converts the Amlabhava in to Madhura bhava, as it contains Amlavarjita pancharasa with dominancy of Katu or Lavana rasa. This co m bined approach gives significant result (P < 0.001) in relieving the symptoms of Amlapitta . K ey wo rds : Amlapitta, Acid peptic disease , Sadyo Vamana, Yavakshara.

Siddhamantra , the Nighantu of early 13 th century AD, written by Vaidyacharya Kesava is now a forgotten work among the lexicons of Indian Materia Medica. Kesava has adopted a reverse method of describing the drugs in this Nighantu . In Siddh amantra the drugs have been arranged according to effect on Dosas. Rasa, Veerya, Vipaka have to be inferred on this basis. Literary research on Siddhamantra was carried out using all available literatures in Dravyagunashastra and clarified with Vopadeva’s Prakasha commentary. Objectives of the stud y we re to establish known botanical source of the medicinal plants mentioned in Siddhamantra through profound literary research, analysing the mode of classification of the drugs in

Anushastra karmas such as Kshara karma, Agnikarma and Raktamoksha na are said to have immediate and long lasting results. Agnikarma is mainly indicated in Ruja pradhana, Vata and Kaphaja vyadhis. Pancha dh a tu shalaka has been used on a regular basis for the purpose of Agnikarma irrespective of the structure involved or l evel of the pathology. But more than 80 % of painful conditions are related to locomotory system which comprises Sandhi, Ast h i, Sira and Sn a yus . These are considered as Gambheera dhatus and Dah a nopakaranas mentioned for th e diseases of these locations are Snigdha dravyas such as K sh audra, Guda, Taila, Vasa, Madhuchista etc . When the thermal behavior of the Snigdha dravyas and Pancha dhatu shalaka were studied by direct methods employed in temperature measurement, Pancha dhatu shalaka requires considerably h igher temperature (235 o C - 240 o C) to become red hot, than that of the Snigdha dravyas to get boil (140 o C - 160 o C) . But Snigdha dravyas has got higher Latent heat than Pancha dhatu shalaka. The heat dissipation rate is about 2 o C in Snigdha dravyas and is 4 o C - 6 o C in Pancha dhatu shalaka. So in conditions like

Vata V yadhis are included under the category of Mahagadas, because of their complex and complicated pathophysiology, clinical features, complications and treatment. Vishvachi is one such Vata ja Nanatmaja Vyadhi whi ch causes the B ahukarma kshaya. It can be compared with brachial neuralgia. To treat this condition effectively a multi therapeutic approac h is essential . The Vata V yadhi C hikitsa comprises the principles like Avarana Bhedana, Shodhana, S hamana and B rhmana . Considering this , a combined approach of Siravyadha followed by P a ncha P rasrutika Niruha B asti was taken and evaluated its efficacy in 20 patients. Here Siravyadha i s Av arana bhedaka and Srotoshodhaka; whereas Basti acts as S hodhaka , Vata shamaka , A nuloma ka and simultaneously it is B al y a and V arn ya . There was a rapid decline of radiating pain immediately after Siravyadha showed a highly significant difference from baseline (P < 0.001). There was a great improvement with respect to restricted movement, pric king sensation and localised pain and tenderness after Basti. The systematic inte rvention of Siravyadha and Basti therapy gives significant result in Vishvachi .