1. Recurrent EGFR-Mutated Non–Small Cell Lung Cancer Discovered by Abnormal Mammogram: Adjuvant/Frontline Metastatic Management Options
- Author
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Shellie Faris, Rudy P. Lackner, Paul Rodriguez, Adam Horn, Thomas Zusag, and Mehmet Sitki Copur
- Subjects
Oncology ,Cancer Research ,medicine.medical_specialty ,Abnormal mammogram ,business.industry ,medicine.medical_treatment ,Melanoma ,medicine.disease ,Malignancy ,respiratory tract diseases ,Lymphoma ,Leukemia ,Internal medicine ,medicine ,Non small cell ,business ,Lung cancer ,Adjuvant - Abstract
Breast metastasis from extramammary malignancy is rare, with a reported incidence rate of 0.4% to 1.3% in the published literature. The primary malignancies that most commonly metastasize to the breast are leukemia, lymphoma, and malignant melanoma. Here, we report a very rare case of metastatic EGFR-mutated non-small cell lung cancer (NSCLC) in the breast detected by screening mammography. The patient had initially been diagnosed with a clinical stage IIIA NSCLC and had been treated with neoadjuvant chemoradiation followed by curative-intent surgery. Several interesting aspects of the case, along with a discussion of evolving adjuvant and frontline metastatic management options in EGFR-mutated NSCLC, will be presented.
- Published
- 2020
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