1. Intraarterial perfusion of prostaglandin E1 after lumbar sympathectomy or reconstruction on femoropopliteal segment.
- Author
-
Davidovic LB, Vranes MR, Lotina SI, Cernak IF, Velimirovic DB, Stojanov PL, Sindjelic RP, Sagic DZ, and Cinara IS
- Subjects
- Alprostadil administration & dosage, Arterial Occlusive Diseases drug therapy, Female, Humans, Infusions, Intra-Arterial, Lumbosacral Region, Male, Middle Aged, Postoperative Care, Salvage Therapy, Alprostadil therapeutic use, Arterial Occlusive Diseases surgery, Femoral Artery surgery, Leg blood supply, Popliteal Artery surgery, Sympathectomy
- Abstract
Out of 100 patients treated by intraarterial perfusion of prostaglandin E1 we selected 36 cases who have been treated after a lumbar sympathectomy or reconstruction on the femoro-popliteal segment. The patients were in the III and IV stage of occlusive diseases by Fontain. All patients were divided into four groups: (a) prostaglandin E1 after a lumbar sympathectomy (20); (b) prostaglandin E1 after failed femoro-popliteal bypass (8); (c) prostaglandin E1 with patent femoro-popliteal bypass and distal progression of the occlusive disease (3); (d) prostaglandin E1 with previously femoro-popliteal reconstruction and poor run off (5). After intraoperative introduction of a catheter into the superficial femoral artery, profunda femoral artery (a, b), a patent graft (c) or just implanted graft (d), a continuous intraarterial perfusion of prostaglandin E1 was applied, in doses 10 nanograms/kg body weight/minute, in total doses 3000 nanograms. The perfusion time was 48-72 h. The patients were controlled immediately after treatment as well as 1, 3, 6 and 12 months after. Our early and late results of the intraarterial perfusion of prostaglandin E1 proved as a very successful limb salvage procedure.
- Published
- 1991