1. Clinical study of transcatheter arterial chemoembolization combined with microwave ablation in the treatment of advanced hepatocellular carcinoma.
- Author
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Li W, Man W, Guo H, and Yang P
- Subjects
- Adult, Aged, Carcinoma, Hepatocellular etiology, Carcinoma, Hepatocellular mortality, Case-Control Studies, Combined Modality Therapy, Female, Humans, Liver Neoplasms etiology, Liver Neoplasms mortality, Male, Middle Aged, Neoplasm Staging, Survival Analysis, Tomography, X-Ray Computed, Treatment Outcome, Carcinoma, Hepatocellular pathology, Carcinoma, Hepatocellular therapy, Catheter Ablation methods, Chemoembolization, Therapeutic, Liver Neoplasms pathology, Liver Neoplasms therapy, Microwaves therapeutic use
- Abstract
Objective: To evaluate the safety and efficacy of transcatheter arterial chemoembolization (TACE) combined with percutaneous microwave ablation (MWA) in the treatment of advanced hepatocellular carcinoma (HCC)., Materials and Methods: Three thousand cases of advanced HCC patients were randomly divided into two groups: 1500 cases in the treatment group were treated with TACE combined with MWA and 1500 cases in the control group were treated with TACE., Results: The effective rate of the treatment group and control group was 71.4% and 42.8%, respectively, and the difference between the two groups was statistically significant (P < 0.05). During the follow-up period at 6, 12, 18, and 24 months postoperatively, the survival rates of the treatment group were 88.1%, 73.8%, 52.3%, and 33.3%, and the survival rates of the control group were 76.2%, 57.1%, 30.9%, and 9.5%, respectively. There was no significant difference in postoperative complications between the two groups., Conclusion: It is safe and effective to use TACE combined with MWA in the treatment of advanced HCC, and the effect of combined treatment is better than that of TACE alone.
- Published
- 2016
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