1. Intercalary membrane as the inner wall overlying optic and chorio-retinal colobomas. Deep penetration Swept Source-OCT study
- Author
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José M. Ruiz-Moreno, Jorge Ruiz-Medrano, Javier A. Montero, and Ignacio Flores-Moreno
- Subjects
Adult ,Male ,medicine.medical_specialty ,optic coloboma ,Abnormalities, Multiple ,Choroid/abnormalities ,Choroid Diseases/diagnosis ,Coloboma/diagnosis ,Female ,Humans ,Middle Aged ,Nerve Fibers/pathology ,Optic Disk/abnormalities ,Optic Nerve Diseases/diagnosis ,Retina/abnormalities ,Retinal Diseases/diagnosis ,Tomography, Optical Coherence/methods ,Chorioretinal coloboma ,subarachnoid space ,swept-source optical coherence tomography ,genetic structures ,Optic Disk ,Nerve fiber layer ,Optic disk ,Case Reports ,Retina ,03 medical and health sciences ,chemistry.chemical_compound ,Nerve Fibers ,0302 clinical medicine ,lcsh:Ophthalmology ,Retinal Diseases ,Optical coherence tomography ,Ophthalmology ,Optic Nerve Diseases ,medicine ,Coloboma ,medicine.diagnostic_test ,Choroid ,business.industry ,Retinal ,Choroid Diseases ,medicine.disease ,eye diseases ,medicine.anatomical_structure ,chemistry ,lcsh:RE1-994 ,030221 ophthalmology & optometry ,Maculopathy ,sense organs ,business ,Tomography, Optical Coherence ,030217 neurology & neurosurgery - Abstract
Five eyes of four patients were studied to analyze the structure of the inner wall of optic and chorioretinal colobomas using swept-source optical coherence tomography (SS-OCT). The colobomatous cavities and their relationship with adjacent structures were examined. SS-OCT permitted the study of the colobomatous cavities in all cases. In four of those cases, a Y-shaped intercalary membrane (ICM) was identified, with an origin in the retinal nerve fiber layer (RNFL), which covered the coloboma and in one case the coloboma was in contact with the vitreous cavity. Vitreous adhesion to the internal wall of the coloboma was found in three cases. No clinical or tomographic maculopathy was observed in any patient. High-resolution deep penetration SS-OCT allows in vivo study of optic and chorioretinal colobomas, identifying the RNFL as the main component of the ICM overlying the colobomatous cavities.
- Published
- 2018
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