11 results on '"Komal Agarwal"'
Search Results
2. Impact of COVID 19 on dermatology education
- Author
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Sudip, Das, Sushil Kumar, Singh, and Komal, Agarwal
- Subjects
Microbiology (medical) ,Infectious Diseases ,Immunology and Allergy ,Dermatology - Published
- 2022
3. Retinitis pigmentosa in Usher syndrome in India: Electronic medical records driven big data analytics: Report III
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Deepika C, Parameswarappa, Anthony Vipin, Das, Mariya Bashir, Doctor, Ramya, Natarajan, Komal, Agarwal, and Subhadra, Jalali
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Male ,Ophthalmology ,Cross-Sectional Studies ,Data Science ,Electronic Health Records ,Humans ,India ,Female ,Usher Syndromes ,Retinitis Pigmentosa - Abstract
To describe the clinical presentation and demographic distribution of retinitis pigmentosa (RP) in patients with Usher syndrome (USH).This is a cross-sectional observational hospital-based study including patients presenting between March 2012 and October 2020. In total, 401 patients with a clinical diagnosis of USH and RP in at least one eye were included as cases. The data were retrieved from the electronic medical record database. For better analysis, all 401 patients were reclassified into three subtypes (type 1, type 2, and type 3) based on the USH criteria.In total, there were 401 patients with USH and RP, with a hospital-based prevalence rate of 0.02% or 2/10,000 population. Further, 353/401 patients were subclassified, with 121 patients in type 1, 146 patients in type 2, and 86 patients in the type 3 USH group. The median age at presentation was 27 years (IQR: 17.5-38) years. There were 246 (61.35%) males and 155 (38.65%) females. Males were more commonly affected in all three subtypes. Defective night vision was the predominant presenting feature in all types of USH (type 1: 43 (35.54%), type 2: 68 (46.58%), and type 3: 40 (46.51%) followed by defective peripheral vision. Patients with type 2 USH had more eyes with severe visual impairment.RP in USH is commonly bilateral and predominantly affects males in all subtypes. Patients with USH and RP will have more affection of peripheral vision than central vision. The key message of our study is early visual and hearing rehabilitation in USH patients with prompt referral to otolaryngologists from ophthalmologists and vice versa.
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- 2022
4. Clinical and visual electrophysiological characteristics of vitelliform macular dystrophies in the first decade of life
- Author
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Srikanta Kumar, Padhy, Deepika C, Parameswarappa, Komal, Agarwal, Brijesh, Takkar, Shashwat, Behera, Bhavik, Panchal, Muralidhar, Ramappa, Tapas Ranjan, Padhi, and Subhadra, Jalali
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Electrooculography ,Ophthalmology ,Retinal Dystrophies ,Humans ,Child ,Eye ,Retrospective Studies ,Vitelliform Macular Dystrophy - Abstract
To evaluate patterns of pediatric vitelliform macular dystrophy (PVMD).This is a retrospective analysis of Indian children with vitelliform macular dystrophy (VMD) presenting within the first decade of life. Records were evaluated for clinical findings, family screening, and investigative findings including optical coherence tomography (OCT), fundus autofluorescence (FAF), full-field electroretinogram (ERG) and electrooculogram (EOG). Electrophysiology was scrutinized and audited for acquisition and interpretation errors. Findings on follow-up were also recorded.46 eyes of 24 patients were included. Mean age at presentation was 7.17 ± 2.17 years. Mean follow-up duration was 1.55 ± 1.69 years. Best disease was the commonest type of VMD detected (21 patients), while autosomal recessive bestrophinopathy was seen in three cases. Mean logMAR BCVA was 0.364 which decreased to 0.402 on follow-up. Hyperopia was noted in 29 out of 46 eyes (mean being +3.87 D, range ebing +0.75 to +8.75 D). Four eyes of four children had choroidal neovascular membrane at presentation, while another child developed while in follow-up. Solid type subretinal deposit was the commonest OCT finding (n = 29/38) and central hyper FAF was the commonest pattern (n = 18/32). EOG was available for review in 32 eyes, but was unreliable in 11 eyes. Seven eyes demonstrated complete absence of light rise on EOG.PVMD can present in advanced forms. Progression to complications with loss of visual acuity can happen within the first decade of life. EOG shows grossly suppressed waveforms in the light phase in a large number of such children.
- Published
- 2022
5. Retinitis pigmentosa in Laurence-Moon-Bardet-Biedl syndrome in India: Electronic medical records driven big data analytics: Report II
- Author
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Deepika C, Parameswarappa, Anthony V, Das, Pratima S, Thakur, Brijesh, Takkar, Prabhjot K, Multani, Srikant K, Padhy, Mariya B, Doctor, Komal, Agarwal, and Subhadra, Jalali
- Subjects
Adult ,Male ,Laurence-Moon Syndrome ,Adolescent ,Data Science ,India ,Blindness ,Young Adult ,Ophthalmology ,Cross-Sectional Studies ,Electronic Health Records ,Humans ,Child ,Bardet-Biedl Syndrome ,Retinitis Pigmentosa - Abstract
To describe the clinical presentation and demographic distribution of retinitis pigmentosa (RP) in Laurence-Moon-Bardet-Biedl (LMBB) syndrome patients.This is a cross-sectional observational hospital-based study wherein 244 patients with RP in LMBB syndrome presenting to our hospital network between March 2012 and October 2020 were included. An electronic medical record database was used for data retrieval.There were 244 patients in total, with a hospital-based prevalence rate of 0.010% or 1000/100,000 population. The mean and median age of patients was 15.22 ± 7.56 and 14 (IQR: 10-18.5) years, respectively, with the majority being in the age group of 11-20 years (133/244 patients; 54.50%). Males were more commonly affected (164 patients; 67.21%), and the majority (182 patients; 74.59%) were students. All 244 patients (100%) complained of defective central vision at presentation. More than one-fourth of the patients had severe visual impairment to blindness at presentation. Prominent retinal feature at presentation was diffuse or widespread retinal pigment epithelial degeneration in all patients.Patients with RP in LMBB syndrome present mainly in the first to second decade of life with severe visual acuity impairment to blindness early in life. It is important to rule out LMBB syndrome in early-onset RP with central visual acuity impairment. On the contrary, all patients diagnosed or suspected with LMBB syndrome systemic features at physician clinic should also be referred for ophthalmic evaluation, low vision assessment, rehabilitation, and vice versa.
- Published
- 2022
6. The role of patch testing with indian cosmetic series in patients with facial pigmented contact dermatitis in India
- Author
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Ayan Samanta, Biswanath Naskar, Komal Agarwal, and Abhishek De
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medicine.medical_specialty ,Lichen planus pigmentosus ,lichen planus pigmentosus ,Indian cosmetic series ,Dermatology ,medicine.disease_cause ,Asymptomatic ,Patch testing ,030207 dermatology & venereal diseases ,03 medical and health sciences ,0302 clinical medicine ,Allergen ,Biopsy ,lcsh:Dermatology ,otorhinolaryngologic diseases ,Medicine ,Facial melanosis ,medicine.diagnostic_test ,business.industry ,lcsh:RL1-803 ,medicine.disease ,Hyperpigmentation ,pigmented contact dermatosis ,patch testin ,Etiology ,Original Article ,medicine.symptom ,business ,Contact dermatitis - Abstract
Background: Pigmented contact dermatitis (PCD) is a non-eczematoid variant of contact dermatitis, mainly characterised by hyperpigmentation. It occurs due to contact with a low amount of allergen over a long duration of time. PCD is frequently seen in Indians but is often misdiagnosed or underdiagnosed because of the asymptomatic nature of the entity. The aetiology and the allergens implicated in PCD in the Indian subcontinent is still an enigma because of the limited studies done. Materials and Methods: This was an institution-based cross-sectional study, done at a tertiary hospital. Patch testing with Indian Cosmetic Series was conducted in a standardised method. Readings were taken at 48 hrs/72 hrs and on the 7th day [Figure 2]a and [Figure 2]b. The International Contact Dermatitis Research Group (ICDRG) scoring system was used to grade the readings. Results: Out of the 38 biopsy proven cases of PCD, 18 (47%) showed lichenoid features, 17 (45%) showed spongiotic features, 3 (8%) showed a mixed lichenoid and spongiotic pattern. Among total 1216 (32 patches × 38 patients) patch applied, 42 (3.4%) showed positivity in 30 patients. Among allergen categories, colorant (PPD) was found to be most common (37%) followed by fragrances (18%), preservatives (15%), anti-microbial (11%) and emulsifier and anti-oxidants (each 8%). Conclusion: It is important to identify the allergens implicated in PCD to help in better management of the condition. Patch testing proves to be a non invasive, low cost method and its role is indispensable in identifying the correct allergen.
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- 2021
7. Sight-threatening intraocular infection in patients with COVID-19 in India
- Author
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Brijesh Takkar, Hrishikesh Kaza, Savitri Sharma, Rajeev R Pappuru, Komal Agarwal, Soumyava Basu, Aditya Kapoor, Niroj Kumar Sahoo, Taraprasad Das, Subhadra Jalali, Hitesh Agrawal, Sameera Nayak, Vivek Pravin Dave, Saumya Jakati, Avinash Pathengay, Raja Narayanan, Mudit Tyagi, Deepika C Parameswarappa, Padmaja Kumari Rani, Vishal Raval, and Shashwat Behera
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Adult ,Male ,medicine.medical_specialty ,medicine.drug_class ,Visual Acuity ,India ,Low molecular weight heparin ,Eye Infections, Bacterial ,Young Adult ,chemistry.chemical_compound ,Endophthalmitis ,Tocilizumab ,Intensive care ,Internal medicine ,Epidemiology ,medicine ,Humans ,intraocular infection ,Retrospective Studies ,SARS-CoV-2 ,business.industry ,endogenous endophthalmitis ,RE1-994 ,medicine.disease ,Anti-Bacterial Agents ,COVID-19 Drug Treatment ,Ophthalmology ,covid-19 ,chemistry ,Intraocular Infection ,Corticosteroid ,Orbital cellulitis ,business ,Eye Infections, Fungal - Abstract
Purpose: Intraocular infection in patients with COVID-19 could be different in the presence of treatment with systemic corticosteroid and immunosuppressive agents. We describe the epidemiology and microbiological profile of intraocular infection in COVID-19 patients after their release from the hospital. Methods: We analyzed the clinical and microbiological data of laboratory-confirmed COVID-19 patients from April 2020 to January 2021 presenting with features of endogenous endophthalmitis within 12 weeks of their discharge from the hospital in two neighboring states in South India. The data included demography, systemic comorbidities, COVID-19 treatment details, time interval to visual symptoms, the microbiology of systemic and ocular findings, ophthalmic management, and outcomes. Results: The mean age of 24 patients (33 eyes) was 53.6 ± 13.5 (range: 5–72) years; 17 (70.83%) patients were male. Twenty-two (91.6%) patients had systemic comorbidities, and the median period of hospitalization for COVID-19 treatment was 14.5 ± 0.7 (range: 7–63) days. Infection was bilateral in nine patients. COVID-19 treatment included broad-spectrum systemic antibiotics (all), antiviral drugs (22, 91.66% of patients), systemic corticosteroid (21, 87.5% of patients), supplemental oxygen (18, 75% of patients), low molecular weight heparin (17, 70.8% of patients), admission in intensive care units (16, 66.6% of patients), and interleukin-6 inhibitor (tocilizumab) (14, 58.3% of patients). Five (20.8%) patients died of COVID-19-related complications during treatment for endophthalmitis; one eye progressed to pan ophthalmitis and orbital cellulitis; eight eyes regained vision >20/400. Fourteen of 19 (73.7%) vitreous biopsies were microbiologically positive (culture, PCR, and microscopy), and the majority (11 patients, 78.5%) were fungi. Conclusion: Intraocular infection in COVID-19 patients is predominantly caused by fungi. We suggest a routine eye examination be included as a standard of care of COVID-19.
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- 2021
8. Focal laser photocoagulation in the management of perifoveal exudative vascular anomalous complex
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Subhakar Reddy, Komal Agarwal, and Hitesh Agrawal
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medicine.medical_specialty ,business.industry ,law ,Ophthalmology ,medicine ,business ,Laser ,law.invention - Published
- 2021
9. Imaging the pediatric retina: An overview
- Author
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Subhadra Jalali, Sameera Nayak, Sushma Jayanna, Anand Vinekar, Komal Agarwal, Parijat Chandra, Bhavik Panchal, Taraprasad Das, and Tapas Ranjan Padhi
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Adult ,Blinding ,Retinal Disorder ,pediatric retinal diseases ,Review Article ,Disease ,Diagnostic Techniques, Ophthalmological ,Retina ,newborn eye screening ,chemistry.chemical_compound ,Retinal Diseases ,lcsh:Ophthalmology ,medicine ,Humans ,Fluorescein Angiography ,Child ,pediatric retina ,medicine.diagnostic_test ,business.industry ,Infant, Newborn ,Fundus photography ,Infant ,Retinal ,Retinopathy of prematurity ,Fluorescein angiography ,medicine.disease ,Ophthalmology ,medicine.anatomical_structure ,chemistry ,retinal imaging ,lcsh:RE1-994 ,Optometry ,business ,Tomography, Optical Coherence - Abstract
Recent decade has seen a shift in the causes of childhood blinding diseases from anterior segment to retinal disease in both developed and developing countries. The common retinal disorders are retinopathy of prematurity and vitreoretinal infections in neonates, congenital anomalies in infants, and vascular retinopathies including type 1 diabetes, tumors, and inherited retinal diseases in children (up to 12 years). Retinal imaging helps in diagnosis, management, follow up and prognostication in all these disorders. These imaging modalities include fundus photography, fluorescein angiography, ultrasonography, retinal vascular and structural studies, and electrodiagnosis. Over the decades there has been tremendous advances both in design (compact, multifunctional, tele-consult capable) and technology (wide- and ultra-wide field and noninvasive retinal angiography). These new advances have application in most of the pediatric retinal diseases though at most times the designs of new devices have remained confined to use in adults. Poor patient cooperation and insufficient attention span in children demand careful crafting of the devices. The newer attempts of hand-held retinal diagnostic devices are welcome additions in this direction. While much has been done, there is still much to do in the coming years. One of the compelling and immediate needs is the pediatric version of optical coherence tomography angiography. These needs and demands would increase many folds in future. A sound policy could be the simultaneous development of adult and pediatric version of all ophthalmic diagnostic devices, coupled with capacity building of trained medical personnel.
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- 2021
10. Response to comments on: Optical coherence tomography angiography in epidemic retinitis
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Hitesh Agarwal, Komal Agarwal, Amelia Janis, and Subhakar Reddy
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medicine.medical_specialty ,business.industry ,Retinitis ,MEDLINE ,Optical coherence tomography angiography ,Retinal Neovascularization ,medicine.disease ,Ophthalmology ,lcsh:Ophthalmology ,lcsh:RE1-994 ,Doxycycline ,medicine ,Humans ,Radiology ,Fluorescein Angiography ,Epidemics ,Letters to the Editor ,business ,Tomography, Optical Coherence - Published
- 2021
11. Pigmentcross 2
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Anupam Das, Komal Agarwal, and Rashmi Sarkar
- Published
- 2017
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