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2. Utility of Urine N-acetyl-β-D-glucosaminidase for Prediction of Renal Damage in Obese Children

Author

Baranak Safaeian, Azar Nickavar, Hossein Zaeri, Lida Lahootian, and Nasser Behnampour

Subjects
Pediatric Obesity, Transplantation, Adolescent, urogenital system, Body Weight, Acute Kidney Injury, urologic and male genital diseases, Cross-Sectional Studies, Nephrology, Case-Control Studies, Child, Preschool, Creatinine, Acetylglucosaminidase, Medicine, Albuminuria, Humans, Child, Biomarkers
Abstract

The incidence of obesity has increased globally in children and adults. In addition, renal dysfunction is an important complication of childhood obesity. This study was performed to identify the diagnostic value of N-acetyl-β-D-glucosaminidase (NAG), a renal injury marker, for the early determination of renal damage in childhood obesity. Totally, 115 obese children and 115 healthy normal weight controls were enrolled in a cross-sectional case–control study. Urine NAG was measured in sample urine and normalized by urine creatinine (CR). In addition, correlation of urine NAG with other variables such as blood pressure (BP), blood glucose, and urine albumin was evaluated. Mean systolic BP (P

Published
2021
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