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By applying enzyme electrophoresis in the agar gel prepared on veronal-medinal buffer (pH 8.6) (the substrate was naphthol AS phosphate; the dye was fast blue B or PP), the authors first revealed mixed salivary alkaline phosphatase (AP) that differed in physicochemical properties from the known serum AP isoforms, in 63% of patients with cholecystitis or pancreatitis, in 90% of those with appendicitis, and in 55.3% of pregnant women with second- and third-degree gestoses. After treatment, the detection rate for salivary AP significantly decreased to 16.6, 40.0, and 6.4%, respectively. This noninvasive test may be useful for the additional diagnosis and monitoring of treatment for abdominal inflammatory diseases and gestational toxicosis.

The study revealed that 92.5% of female patients consulted by themselves the physician on the subject of mastopathy were town inhabitants with secondary special and humanitarian higher education from the white-collar social group. The concomitant diseases of digestial organs and urogenital system and the deviant psychological characteristics of personality as well had been registered reliably much more frequently among women with a mastopathy in comparison with the control group. More than 70% of females noted the intensification of mastopathy symptoms after the exacerbation of somatic diseases and nervous stresses. Also, more than 80% of female patients experienced psychological discomfort due to doctor's referral to the oncological dispensary. In authors'judgment, the special-purpose mammological consulting rooms under maternity welfare clinics and polyclinics has to be organized to provide efficient diagnostics, treatment and psychological adjustment of female patients with benignant diseases of mammary glands.

Immunodiffusion assays were used to examine lactoferrin (LF) in the mixed saliva of 1026 patients and 553 apparently healthy individuals. Elevated salivary LF levels were found in respiratory and digestive diseases and diabetes. It is concluded that this non-invasive immunochemical assay is promising in the screening and monitoring of persons during their health examination.

Immunochemical testing of salivary samples of 73 patients revealed a positive correlation between increased level of lactoferrin and the presence of chronic pancreatoduodenal diseases (gastroduodenitis, gastroduodenal ulcers, polyps of the antral portion of the stomach, cholecystitis, cholangitis, cholelithiasis, hepatitis, and pancreatitis, correlation coefficient 0.9). The test is proposed as a cheap and informative method for screening of the above diseases.