1. Combined Fractional Treatment of Acne Scars Involving Non-ablative 1,550-nm Erbium-glass Laser and Micro-needling Radiofrequency: A 16-week Prospective, Randomized Split-face Study
- Author
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Jae Yoon Jung, Sun Chul Choi, Hae Young Park, Hyuck Hoon Kwon, Chanhee Kang, Youin Bae, and Gyeong-Hun Park
- Subjects
Adult ,Male ,inorganic chemicals ,Time Factors ,Seoul ,Cosmetic Techniques ,Lasers, Solid-State ,Dermatology ,law.invention ,Cicatrix ,Young Adult ,030207 dermatology & venereal diseases ,03 medical and health sciences ,Glass laser ,radiofrequency ,0302 clinical medicine ,Randomized controlled trial ,law ,Acne Vulgaris ,Photography ,Humans ,Medicine ,Combined Modality Therapy ,Non ablative ,Prospective Studies ,Low-Level Light Therapy ,Prospective cohort study ,Acne scars ,Dry needling ,business.industry ,acnescar ,technology, industry, and agriculture ,lasersurgery ,General Medicine ,body regions ,Regimen ,Treatment Outcome ,Needles ,RL1-803 ,030220 oncology & carcinogenesis ,fractionalphotothermolysis ,Female ,business ,Nuclear medicine - Abstract
An optimized therapeutic regimen involving a non-ablative fractionated laser or radiofrequency therapy for acne scars has not yet been established. To evaluate whether the combination of a non-ablative fractional laser (NAF) and fractional micro-needling radiofrequency (FMR) has clinical advantages for the treatment of atrophic acne scars compared with NAF alone, a 16-week prospective, randomized split-face study was performed. Each facial side of a patient was treated with 3 sessions of either NAF with FMR or NAF alone, with a 4-week interval between each session. Although both sides demonstrated significant decreases in the échelle d’évaluation clinique des cicatrices d’acné (ECCA) score, the facial side treated using the combination regimen demonstrated greater improvement in ECCA score regarding degree and onset time than the NAF-treated side. Histopathological and immunohistochemical results confirmed the clinical findings. This study demonstrated that a combination regimen involving NAF and FMR could be a viable option with satisfactory efficacy.
- Published
- 2017