1. [Immunomorphological aspects of post-traumatic subatrophy of the eyeball].
- Author
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Filatova IA, Mokhammad IM, Shemetov SA, Kondratyeva UP, Balatskaya NV, and Denisyuk VO
- Subjects
- Humans, Eye, Inflammation, Eye Injuries complications, Eye Injuries diagnosis, Contusions
- Abstract
Purpose: The study attempts to characterize immunomorphological disorders at different degrees of post-traumatic subatrophy of the eyeball., Material and Methods: The study included 123 patients with blind and unpromising eyes, eyeball subatrophy of various degrees, who were divided into three groups (1, 2 and 3) depending on the degree of eyeball subatrophy., Results: The greatest risk of autoimmune inflammation was observed in patients with degree I subatrophy. Contusion injury of the eye was proven to not exclude the course of post-traumatic autoimmune uveitis. The development of post-traumatic subatrophic process is associated with activation of systemic organ-specific immunity, shift of balance in main regulatory subpopulations., Conclusion: The study showed that the most severe clinical course of chronic post-traumatic uveitis is observed in patients as a result of penetrating trauma to the eyeball. The contusion nature of such ocular injury does not exclude the development of autoimmune inflammation.
- Published
- 2023
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