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Start Over Descriptor "microPAD" Publisher mdpi ag
2 results on '"microPAD"'

1. Chronometric Quantitation of Analytes in Paper-Based Microfluidic Devices (MicroPADs) via Enzymatic Degradation of a Metastable Biomatrix

Author

Aditya R. Jangid, E. Brandon Strong, Emiliano Escamilla, Brittany A. Lore, Nicholas J. Tod, Robert Thiel, Andres W. Martinez, and Nathaniel W. Martinez

Subjects
microfluidic paper-based analytical device, µPAD, microPAD, point-of-care, diagnostics, microfluidics, wax printing, immunoassays, analytical chemistry, Engineering machinery, tools, and implements, TA213-215, Technological innovations. Automation, HD45-45.2
Abstract

The following article summarizes United States Patent Application No. US20180052155A1, titled ‘Assay Devices and Methods’ (filed 16 August 2016, published 22 February 2018). While lateral flow assays (LFAs) have revolutionized point-of-care diagnostics by enabling accurate, inexpensive, and rapid detection of biomarkers, they typically do not provide quantitative results. Hence, there is a significant need for quantitative assays at the point of care. This patent summary describes a novel method of chronometric biomarker quantitation via enzymatic degradation of a metastable gelatin-based biomatrix, principally suited for use in paper-based microfluidic devices (microPADs). This new quantitation mechanism was designed to meet the ASSURED criteria for point-of-care diagnostic devices laid forth by the World Health Organization and may ultimately provide increased access to healthcare, at a significantly reduced cost, around the world.

Published
2019
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2. Chronometric Quantitation of Analytes in Paper-Based Microfluidic Devices (MicroPADs) via Enzymatic Degradation of a Metastable Biomatrix

Author

Emiliano Escamilla, E. Bradley Strong, Nicholas J. Tod, Robert Thiel, Andres W. Martinez, Brittany A. Lore, Nathaniel W. Martinez, and Aditya Jangid

Subjects
Analyte, µPAD, lcsh:Engineering machinery, tools, and implements, Computer science, Microfluidics, microfluidics, Nanotechnology, 02 engineering and technology, 01 natural sciences, Rapid detection, World health, microPAD, wax printing, analytical chemistry, diagnostics, lcsh:Technological innovations. Automation, Point of care, lcsh:HD45-45.2, 010401 analytical chemistry, microfluidic paper-based analytical device, General Engineering, Paper based, 021001 nanoscience & nanotechnology, 0104 chemical sciences, immunoassays, point-of-care, lcsh:TA213-215, 0210 nano-technology, Enzymatic degradation
Abstract

The following article summarizes United States Patent Application No. US20180052155A1, titled ‘Assay Devices and Methods’ (filed 16 August 2016, published 22 February 2018). While lateral flow assays (LFAs) have revolutionized point-of-care diagnostics by enabling accurate, inexpensive, and rapid detection of biomarkers, they typically do not provide quantitative results. Hence, there is a significant need for quantitative assays at the point of care. This patent summary describes a novel method of chronometric biomarker quantitation via enzymatic degradation of a metastable gelatin-based biomatrix, principally suited for use in paper-based microfluidic devices (microPADs). This new quantitation mechanism was designed to meet the ASSURED criteria for point-of-care diagnostic devices laid forth by the World Health Organization and may ultimately provide increased access to healthcare, at a significantly reduced cost, around the world.

Published
2019

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