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Start Over Author "Yamatani, Akimasa" Publisher mdpi ag
10 results on '"Yamatani, Akimasa"'

4. The Current States, Challenges, Ongoing Efforts, and Future Perspectives of Pharmaceutical Excipients in Pediatric Patients in Each Country and Region

Author

Saito, Jumpei, primary, Agrawal, Anjali, additional, Patravale, Vandana, additional, Pandya, Anjali, additional, Orubu, Samuel, additional, Zhao, Min, additional, Andrews, Gavin P., additional, Petit-Turcotte, Caroline, additional, Landry, Hannah, additional, Croker, Alysha, additional, Nakamura, Hidefumi, additional, Yamatani, Akimasa, additional, and Salunke, Smita, additional

Published
2022
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6. Swallowability of Minitablets among Children Aged 6–23 Months: An Exploratory, Randomized Crossover Study

Author

Mitsui, Nao, primary, Hida, Noriko, additional, Kamiya, Taro, additional, Yamazaki, Taigi, additional, Miyazaki, Kazuki, additional, Saito, Kiyomi, additional, Saito, Jumpei, additional, Yamatani, Akimasa, additional, Ishikawa, Yoichi, additional, Nakamura, Hidefumi, additional, Nakamura, Akihiro, additional, and Harada, Tsutomu, additional

Published
2022
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7. Exploring Acceptability Drivers of Oral Antibiotics in Children: Findings from an International Observational Study

Author

Vallet, Thibault, primary, Bensouda, Yahya, additional, Saito, Jumpei, additional, Mathiesen, Liv, additional, Pokharkar, Varsha, additional, Klingmann, Viviane, additional, Peak, Matthew, additional, Elhamdaoui, Omar, additional, Yamatani, Akimasa, additional, Ivanovic, Ivana, additional, Sajith, Manjusha, additional, Münch, Juliane, additional, Bracken, Louise, additional, Duncan, Jennifer Claire, additional, Salunke, Smita, additional, Wang, Siri, additional, and Ruiz, Fabrice, additional

Published
2021
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10. Study on the Preparation Method of Quality-Assured In-Hospital Drug Formulation for Children-A Multi-Institutional Collaborative Study.

Author

Saito J, Suzuki E, Nakamura Y, Otsuji T, Yamamoto H, Yamamoto H, Kai Y, Totsu M, Hashimoto S, Nakamura H, Akabane M, and Yamatani A

Abstract

The quality-assured preparation of crushed and diluted preparations for children is a challenge. In this study, a multicenter study was conducted to validate the preparation method for the quality assurance of baclofen powder, clonidine powder, and hydrocortisone powder prepared from tablets according to a previously established method. In-hospital preparations were prepared at five medical facilities under different crushing and mixing conditions. After storage in closed bottles, in-use bottles, and laminated paper for 120 days, ingredients stability, drug elution, and content uniformity after packaging were evaluated. All three ingredients were maintained at between 90% and 110% of their initial content for 120 days under packaging conditions of 25 ± 2 °C and 60 ± 5% relative humidity, with no change in dissolution in all formulations made at all five facilities. The content uniformity was also acceptable. The established method may contribute to quality-assured pediatric dosage form modification.

Published
2023
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