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Industry Revolution 4.0 connects the Internet of Things (IoT) resource-constrained devices to Smart Factory solutions and delivers insights. As a result, a complex and dynamic network with a vulnerability inherited from the Internet becomes an attractive target for hackers to attack critical infrastructures. Therefore, this paper selects three potential attacks with the evaluation of the protections, namely (1) distributed denial of service (DDoS), (2) address resolution protocol (ARP) spoofing, and (3) Internet protocol (IP) fragmentation attacks. In the DDoS protection, the F1-score, accuracy, precision, and recall of the four-feature random forest with principal component analysis (RFPCA) model are 95.65%, 97%, 97.06%, and 94.29%, respectively. In the ARP spoofing, a batch processing method adopts the entropy calculated in the 20 s window with sensitivity to network abnormalities detection of various ARP spoofing scenarios involving victims’ traffic. The detected attacker’s MAC address is inserted in the block list to filter malicious traffic. The proposed protection in the IP fragmentation attack is implementing one-time code (OTC) and timestamp fields in the packet header. The simulation shows that the method detected 160 fake fragments from attackers among 2040 fragments.

A growing portfolio of research has been reported on the use of machine learning-based architectures and models in the domain of healthcare. The development of data-driven applications and services for the diagnosis and classification of key illness conditions is challenging owing to issues of low volume, low-quality contextual data for the training, and validation of algorithms, which, in turn, compromises the accuracy of the resultant models. Here, a fusion machine learning approach is presented reporting an improvement in the accuracy of the identification of diabetes and the prediction of the onset of critical events for patients with diabetes (PwD). Globally, the cost of treating diabetes, a prevalent chronic illness condition characterized by high levels of sugar in the bloodstream over long periods, is placing severe demands on health providers and the proposed solution has the potential to support an increase in the rates of survival of PwD through informing on the optimum treatment on an individual patient basis. At the core of the proposed architecture is a fusion of machine learning classifiers (Support Vector Machine and Artificial Neural Network). Results indicate a classification accuracy of 94.67%, exceeding the performance of reported machine learning models for diabetes by ~1.8% over the best reported to date.