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Your search keyword '"Spitzweg, Christine"' showing total 11 results
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11 results on '"Spitzweg, Christine"'

1. Treatment of RET-Positive Advanced Medullary Thyroid Cancer with Multi-Tyrosine Kinase Inhibitors—A Retrospective Multi-Center Registry Analysis

Author

Koehler, Viktoria Florentine, primary, Adam, Pia, additional, Fuss, Carmina Teresa, additional, Jiang, Linmiao, additional, Berg, Elke, additional, Frank-Raue, Karin, additional, Raue, Friedhelm, additional, Hoster, Eva, additional, Knösel, Thomas, additional, Schildhaus, Hans-Ulrich, additional, Negele, Thomas, additional, Siebolts, Udo, additional, Lorenz, Kerstin, additional, Allelein, Stephanie, additional, Schott, Matthias, additional, Spitzweg, Christine, additional, and Kroiss, Matthias, additional

Published
2022
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2. Preoperative Imaging with [18F]-Fluorocholine PET/CT in Primary Hyperparathyroidism

Author

Dekorsy, Franziska J., primary, Beyer, Leonie, additional, Spitzweg, Christine, additional, Schmidmaier, Ralf, additional, Todica, Andrei, additional, Trupka, Arnold, additional, Cyran, Clemens C., additional, Berger, Frank, additional, Ladurner, Roland, additional, Zimmermann, Petra, additional, Knösel, Thomas, additional, Bartenstein, Peter, additional, Lottspeich, Christian, additional, and Wenter, Vera, additional

Published
2022
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3. Course of Disease and Clinical Management of Patients with Poorly Differentiated Thyroid Carcinoma

Author

Grawe, Freba, primary, Cahya, Atika, additional, Fabritius, Matthias P., additional, Beyer, Leonie, additional, Wenter, Vera, additional, Ruebenthaler, Johannes, additional, Geyer, Thomas, additional, Burgard, Caroline, additional, Bartenstein, Peter, additional, Ilhan, Harun, additional, Spitzweg, Christine, additional, and Todica, Andrei, additional

Published
2021
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6. Distinct Expression Patterns of VEGFR 1-3 in Gastroenteropancreatic Neuroendocrine Neoplasms: Supporting Clinical Relevance, but not a Prognostic Factor

Author

Bösch, Florian, primary, Altendorf-Hofmann, Annelore, additional, Jacob, Sven, additional, Auernhammer, Christoph J., additional, Spitzweg, Christine, additional, Boeck, Stefan, additional, Schubert-Fritschle, Gabriele, additional, Werner, Jens, additional, Kirchner, Thomas, additional, Angele, Martin K., additional, and Knösel, Thomas, additional

Published
2020
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11. Preoperative Imaging with [ 18 F]-Fluorocholine PET/CT in Primary Hyperparathyroidism.

Author

Dekorsy FJ, Beyer L, Spitzweg C, Schmidmaier R, Todica A, Trupka A, Cyran CC, Berger F, Ladurner R, Zimmermann P, Knösel T, Bartenstein P, Lottspeich C, and Wenter V

Abstract

Primary hyperparathyroidism (pHPT) is a common endocrine disorder due to hyperfunctioning parathyroid glands. To date, the only curing therapy is surgical removal of the dysfunctional gland, making correct detection and localization crucial in order to perform a minimally invasive parathyroidectomy. 18 F-Fluorocholine positron emission tomography/computed tomography ( 18 F-FCH PET/CT) has shown promising results for the detection of pHPT, suggesting superiority over conventional imaging with ultrasounds or scintigraphy. A total of 33 patients with pHPT who had negative or equivocal findings in conventional imaging received 18 F-FCH PET/CT preoperatively and were retrospectively included. A pathological hyperfunctional parathyroid gland was diagnosed in 24 cases (positive PET, 72.7%), 4 cases showed equivocal choline uptake (equivocal PET, 12.1%), and in 5 cases, no enhanced choline uptake was evident (negative PET, 15.2%). Twelve of the twenty-four detected adenoma patients underwent surgery, and in all cases, a pathological parathyroid adenoma was resected at the site detected by PET/CT. Two of the six patients without pathological choline uptake who received a parathyroidectomy revealed no evidence of parathyroid adenoma tissue in the histopathological evaluation. This retrospective study analyzes 18 F-FCH PET/CT in a challenging patient cohort with pHPT and negative or equivocal conventional imaging results and supports the use of 18 F-FCH for the diagnosis of hyperfunctional parathyroid tissue, especially in this patient setting, with a 100% true positive and true negative detection rate. Our study further demonstrates the importance of 18 F-FCH PET/CT for successful surgical guidance.

Published
2022
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