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21 results on '"Necozione, Stefano"'

4. Serum Uric Acid Levels Are Associated with the Echogenic Features of Carotid Plaque Vulnerability in Elderly Patients with Atherosclerotic Disease

Author

Mastroiacovo, Daniela, primary, Ettorre, Evaristo, additional, Mengozzi, Alessandro, additional, Virdis, Agostino, additional, Camerota, Antonio, additional, Muselli, Mario, additional, Necozione, Stefano, additional, Bocale, Raffaella, additional, Ferri, Claudio, additional, and Desideri, Giovambattista, additional

Published
2023
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6. Enhanced Carotid Plaque Echolucency Is Associated with Reduced Cognitive Performance in Elderly Patients with Atherosclerotic Disease Independently on Metabolic Profile

Author

Mastroiacovo, Daniela, primary, Mengozzi, Alessandro, additional, Dentali, Francesco, additional, Pomero, Fulvio, additional, Virdis, Agostino, additional, Camerota, Antonio, additional, Muselli, Mario, additional, Necozione, Stefano, additional, Bocale, Raffaella, additional, Ferri, Claudio, additional, and Desideri, Giovambattista, additional

Published
2023
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10. E-Learning Satisfaction, Stress, Quality of Life, and Coping: A Cross-Sectional Study in Italian University Students a Year after the COVID-19 Pandemic Began

Author

Cofini, Vincenza, primary, Perilli, Enrico, additional, Moretti, Annalucia, additional, Bianchini, Valeria, additional, Perazzini, Matteo, additional, Muselli, Mario, additional, Lanzi, Sabrina, additional, Tobia, Loreta, additional, Fabiani, Leila, additional, and Necozione, Stefano, additional

Published
2022
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14. Association of Colonic Diverticula with Colorectal Adenomas and Cancer

Author

Viscido, Angelo, primary, Ciccone, Fabiana, additional, Vernia, Filippo, additional, Gabrieli, Dolores, additional, Capannolo, Annalisa, additional, Stefanelli, Gianpiero, additional, Necozione, Stefano, additional, Valerii, Giorgio, additional, Ashktorab, Hassan, additional, and Latella, Giovanni, additional

Published
2021
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16. Improvement of Executive Function after Short-Term Administration of an Antioxidants Mix Containing Bacopa, Lycopene, Astaxanthin and Vitamin B12: The BLAtwelve Study

Author

Crosta, Francesca, primary, Stefani, Amanda, additional, Melani, Francesco, additional, Fabrizzi, Paolo, additional, Nizzardo, Andrea, additional, Grassi, Davide, additional, Bocale, Raffaella, additional, Necozione, Stefano, additional, Lombardi, Francesca, additional, Castelli, Vanessa, additional, Cicero, Arrigo F. G., additional, Cimini, Annamaria, additional, Ferri, Claudio, additional, and Desideri, Giovambattista, additional

Published
2020
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18. Association between Corrected QT Interval and C-Reactive Protein in Patients with Inflammatory Bowel Diseases

Author

Viscido, Angelo, primary, Capannolo, Annalisa, additional, Petroni, Renata, additional, Stefanelli, Gianpiero, additional, Zerboni, Giulia, additional, De Martinis, Massimo, additional, Necozione, Stefano, additional, Penco, Maria, additional, Frieri, Giuseppe, additional, Latella, Giovanni, additional, and Romano, Silvio, additional

Published
2020
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20. Is It Possible to Establish a Reliable Correlation between Maximum Standardized Uptake Value of 18-Fluorine Fluorodeoxyglucose Positron Emission Tomography/Computed Tomography and Histological Types of Non-Small Cell Lung Cancer? Analysis of the Italian VATS Group Database

Author

Divisi, Duilio, Rinaldi, Marta, Necozione, Stefano, Curcio, Carlo, Rea, Federico, Zaraca, Francesco, De Vico, Andrea, Zaccagna, Gino, Di Leonardo, Gabriella, Crisci, Roberto, and On Behalf Of The Italian Vats Group, Null

Subjects
Medicine (General), medicine.medical_specialty, 18F-FDG-PET/CT, Clinical Biochemistry, VATS lobectomy, Standardized uptake value, NSCLC, Article, R5-920, biological framework, SUVmax, VATS group, data quality, Post-hoc analysis, medicine, Lung cancer, medicine.diagnostic_test, business.industry, Histology, medicine.disease, Positron emission tomography, Adenocarcinoma, Histopathology, Nuclear medicine, business
Abstract

Background. Although positron emission tomography/computed tomography, often integrated with 2-deoxy-2-[fluorine-18] fluorine-D-glucose (18F-FDG-PET/CT), is fundamental in the assessment of lung cancer, the relationship between metabolic avidity of different histotypes and maximum standardized uptake value (SUVmax) has not yet been thoroughly investigated. The aim of the study is to establish a reliable correlation between Suvmax and histology in non-small cell lung cancer (NSCLC), in order to facilitate patient management. Methods. We retrospectively assessed the data about lung cancer patients entered in the Italian Registry of VATS Group from January 2014 to October 2019, after establishing the eligibility criteria of the study. In total, 8139 patients undergoing VATS lobectomy were enrolled: 3260 females and 4879 males. The relationship between SUVmax and tumor size was also analyzed. Results. The mean values of SUVmax in the most frequent types of lung cancer were as follows: (a) 4.88 ± 3.82 for preinvasive adenocarcinoma; (b) 5.49 ± 4.10 for minimally invasive adenocarcinoma; (c) 5.87 ± 4.18 for invasive adenocarcinoma; and (d) 8.85 ± 6.70 for squamous cell carcinoma. Processing these data, we displayed a statistically difference (p < 0.000001) of FDG avidity between adenocarcinoma and squamous cell carcinoma. Moreover, by classifying patients into five groups based on tumor diameter and after evaluating the SUVmax value for each group, we noted a statistical correlation (p < 0.000001) between size and FDG uptake, also confirmed by the post hoc analysis. Conclusions. There is a correlation between SUVmax, histopathology outcomes and tumor size in NSCLC. Further clinical trials should be performed in order to confirm our data.

Published
2021
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21. Vaccine Acceptance in Patients with Inflammatory Bowel Disease: Lessons Learned from the COVID-19 Pandemic.

Author

Mastrangeli G, Vernia F, Necozione S, Muselli M, Frassino S, Cesaro N, Latella G, and Fabiani L

Abstract

Background: Immunomodulating therapies, which are commonly used in patients with Crohn's disease (CD) and ulcerative colitis (UC), have been linked to an increased risk of contracting opportunistic infectious diseases, the majority of which are preventable through vaccination. Nonetheless, vaccination rates in these patients are suboptimal, and frequently lower than in the general population. The COVID-19 immunization schedule provided a new scenario for investigating vaccine acceptance in patients with inflammatory bowel disease (IBD), with uncertainty and concerns emerging and the number of subjects receiving the third and fourth doses of the vaccine gradually decreasing. This study investigated IBD patients' attitudes towards previous COVID-19 vaccine programs and identified the factors that influence their adherence. It considered demographic and disease-related factors as well as the role of gastroenterologists and primary care physicians (PCPs)., Methods: Data were collected through a self-completed questionnaire administered to all adult IBD patients (age > 18) who visited the Gastroenterology, Hepatology, and Nutrition division at the University of L'Aquila (Italy) for a regular follow-up between November 2021 and December 2022. Non-IBD gastroenterological outpatients who visited during the same period were included as a control group., Results: A total of 178 patients were included in the analysis. The IBD group consisted of 77 patients, 48.1% with CD and 51.9% with UC; the mean age was 49.5 years and 51.9% were female. Overall, 94.8% of IBD patients had undergone at least one vaccine dose and 79.2% had received two doses, versus 8% of the control group ( p < 0.0001). A total of 84.4% of IBD patients reported their propensity towards COVID-19 vaccination, with an average agreement score significantly higher than the controls ( p = 0.0044). The trust of IBD patients in the effectiveness of the COVID-19 vaccine ( p < 0.0001) and its role in hastening pandemic resolution ( p < 0.0001) is strongly related to motivation and propensity. Concerns about the safety of the COVID-19 vaccine in IBD ( p = 0.0202) and fear of vaccine-induced flare-ups ( p = 0.0192) were reported as the main barriers. No correlation was found between COVID-19 vaccine propensity and clinical features like the type of IBD, years of disease, activity, and ongoing treatment. Regarding the recommendations received from physicians to get vaccinated against COVID-19, IBD patients relied heavily on their gastroenterologists for advice, while the control group relied mainly on their PCPs., Conclusions: The overall positive attitude towards vaccinations reported in our study was better than that observed for other vaccines. The relationship of trust with the gastroenterologist should be used to boost vaccination against other preventable diseases in IBD patients. Our findings add information on the factors influencing vaccine propensity, which can be used to improve current vaccination strategies.

Published
2024
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