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15 results on '"Koşar, Ali"'

4. Biomedical Applications of Microfluidic Devices: A Review

Author

Gharib, Ghazaleh, primary, Bütün, İsmail, additional, Muganlı, Zülâl, additional, Kozalak, Gül, additional, Namlı, İlayda, additional, Sarraf, Seyedali Seyedmirzaei, additional, Ahmadi, Vahid Ebrahimpour, additional, Toyran, Erçil, additional, van Wijnen, Andre J., additional, and Koşar, Ali, additional

Published
2022
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7. Influence of Fluid Properties on Intensity of Hydrodynamic Cavitation and Deactivation of Salmonella typhimurium

Author

Gevari, Moein Talebian, Parlar, Ayhan, Torabfam, Milad, Koşar, Ali, Yüce, Meral, and Ghorbani, Morteza

Subjects
lcsh:Chemistry, lcsh:QD1-999, hydrodynamic cavitation, microfluidics, bacteria deactivation, lcsh:TP1-1185, water treatment, salmonella typhimurium, lcsh:Chemical technology
Abstract

In this study, three microfluidic devices with different geometries are fabricated on silicon and are bonded to glass to withstand high-pressure fluid flows in order to observe bacteria deactivation effects of micro cavitating flows. The general geometry of the devices was a micro orifice with macroscopic wall roughness elements. The width of the microchannel and geometry of the roughness elements were varied in the devices. First, the thermophysical property effect (with deionized water and phosphate-buffered saline (PBS)) on flow behavior was revealed. The results showed a better performance of the device in terms of cavitation generation and intensity with PBS due to its higher density, higher saturation vapor pressure, and lower surface tension in comparison with water. Moreover, the second and third microfluidic devices were tested with water and Salmonella typhimurium bacteria suspension in PBS. Accordingly, the presence of the bacteria intensified cavitating flows. As a result, both devices performed better in terms of the intensity of cavitating flow with the presence of bacteria. Finally, the deactivation performance was assessed. A decrease in the bacteria colonies on the agar plate was detected upon the tenth cycle of cavitating flows, while a complete deactivation was achieved after the fifteenth cycle. Thus, the proposed devices can be considered as reliable hydrodynamic cavitation reactors for &ldquo, water treatment on chip&rdquo, applications.

Published
2020

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