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Digital Image Correlation (DIC) often encounters challenges with variability and consistency in traditional speckle pattern application techniques, such as spray-painting, affecting measurement accuracy and reliability. This study evaluates a film-free water decal method as an alternative for applying speckle patterns in DIC. SS275 structural steel specimens were prepared with speckle patterns using both the film-free water decal method and traditional spray-painting. The quality of the speckle patterns was assessed, and their effectiveness for DIC was evaluated through tensile testing and a comparison with strain gauge measurements. The film-free water decal method provided enhanced control over speckle pattern application, resulting in high-quality, consistent patterns. Strain measurements obtained using this method closely matched those from traditional methods, confirming its reliability. The film-free water decal method offers a practical and reliable alternative to spray-painting, improving the consistency and accuracy of DIC experiments, with potential applications in various engineering and scientific fields.

Background and Objectives: The Clinical Frailty Scale (CFS), used to screen for prehospital frailty in patients aged >65 years, is simple, time-efficient, and has been validated in emergency departments (EDs). In this study, we analyzed whether the Korean Triage and Acuity Scale (KTAS) classification by level in older patients determined to have frailty based on the Korean version of the CFS increases the triage performance of the current KTAS. Materials and Methods: The primary outcome was 30-day in-hospital mortality, and secondary outcomes were hospital and intensive care unit (ICU) admissions. This study retrospectively analyzed prospectively collected data from three ED centers. Patients with a CFS score ranging from five (mildly frail) to nine (terminally ill) were categorized into the frailty group. We upgraded the KTAS classification of the frailty group by one level of urgency and defined this as the CFS-KTAS. Results: The cutoff values for predicting admission were three and two for the KTAS and CFS-KTAS, respectively. A significant difference was observed in the area under the receiver operating characteristic (AUROC) curve between the KTAS and CFS-KTAS. To predict ICU admission, the cutoff score was two for both scales. A significant difference was observed in the AUROC curve between the KTAS and CFS-KTAS. For predicting in-hospital mortality, the cutoff score was two for both scales. A significant difference was observed in the AUROC curve between the KTAS and CFS-KTAS. Conclusions: This study showed that the CFS-adjusted KTAS has a more useful prognostic value than the KTAS alone for predicting hospital outcomes in older patients.

The seismic design of structures is crucial for preventing structural collapse and safeguarding human lives. Buckling-restrained braces (BRBs) have emerged as effective seismic protection devices due to their high stiffness, strength, and exceptional energy absorption capabilities. Typically, a conventional BRB consists of a steel core surrounded by concrete-filled steel tubes, with a separation mechanism ensuring axial-only deformation of the core. However, researchers have been increasingly focusing on developing innovative BRB designs with enhanced performance, incorporating different materials and configurations. This paper presents a comprehensive analysis of the development of novel BRBs introduced in the past 15 years. A systematic review approach is adopted, and the selected articles are categorized based on the shapes, materials, and compositions of the BRB components. Although carbon steel has been widely used in numerous studies, its susceptibility to corrosion and its potential impact on the hysteretic behavior of BRBs remain unexplored. Consequently, future research prospects are identified, highlighting the significance of employing anti-corrosive materials in fabricating BRBs to ensure their stable seismic performance under harsh environmental conditions. Investigating novel materials and configurations can lead to the creation of more robust and corrosion-resistant BRBs, thus enhancing the safety and longevity of structures in earthquake-prone areas.

Passive energy dissipation systems and devices are helpful in mitigating the danger of earthquake damage to structures. Metallic slit dampers (MSDs) are one of the most efficient and cost-effective solutions for decreasing seismic energy intake. The potential importance of MSDs in managing vibrations and limiting structural fatigue continues to grow as research advances and new materials and designs are introduced. This study evaluated the seismic performance of single-plate MSDs (SPMSDs) through a combination of numerical simulation and assessment of experimental results. ABAQUS software was used to create an assembly consisting of endplates, bolts, and SPMSDs. A real-world earthquake scenario was simulated using cyclic loads based on ASCE/SEI standards, and displacement-measuring devices such as strain gauges and LVDT were employed to record the behavior of the SPMSDs. The results of the experiment are used to assess the compliance of the SPMSDs and discuss their behavior as they undergo minimum and maximum displacements due to minimum and maximum applied forces. The energy dissipation capabilities of the dampers are presented by analyzing and comparing the area of their hysteresis loops, equivalent viscous damping, and their damping ratios. Actual failure modes are identified and shown to describe the limitations and potential vulnerability of the dampers. The relative error between the lowest and greatest recorded forces from experimental data and numerical simulation ranges from 4.4% to 5.7% for SPMSD 1 and from 1.6% to 2.1% for SPMSD 2, respectively. These deviation values represent a satisfactory level of precision, demonstrating that the numerical simulation accurately predicts the actual performance and behavior of the dampers when subjected to cyclic stress. The topology optimization performed in this study yielded an improved geometry of the SPMSD suited for a corresponding maximum considered earthquake (MCER) displacement of ±33 mm. This research also suggests practical implementations of the investigated and improved SPMSDs.

This study presents a numerical analysis to reduce the overpressure inside protective tunnels for external detonations. A three-dimensional computational fluid dynamics model of a tunnel subjected to detonation for a hemispherical charge with a charge weight of 555 kg and a standoff distance of 7.6 m was established, based on a mesh sensitivity study to obtain an optimal element size, stability analysis of overpressure, and validation study to evaluate the accuracy of the numerical results based on Unified Facilities Criteria (UFC) 3-340-02. A parametric analysis was performed using the validated numerical model to investigate the effects of the entrance shape and blast pockets on the reduction in the maximum overpressure. The maximum overpressures were effectively reduced as the slope angle of the tunnel entrance decreased and the length of the blast pocket divided by the tunnel width decreased. An optimized shape of the tunnel was proposed based on the numerical results, where the peak overpressures were reduced by a maximum of 64.5%. This study aims to protect facilities, personnel, and equipment and further reduce construction costs by lowering the overpressure rating of blast valves in protective tunnels.

The early discovery of factors that compromise a civil infrastructure’s structural integrity allows for safety monitoring, timely prevention, and a prompt remedy to the discovered problem. As a result, researchers have been researching various methodologies and types of structural health monitoring (SHM). A systematic search was performed following the updated Preferred Reporting Items for Systematic reviews and Meta-Analyses (PRISMA 2020) in Scopus and ScienceDirect from Elsevier, Google Scholar, MDPI, Springer, Wiley Online and ASCE Library, EOP and IOP Science, IEEE, and other databases with the reliable peer review process. From 1480 identified pieces of literature, one hundred and nine (109) sources met the criteria for inclusion and exclusion and were used to produce our findings. This study presents the identified purpose and application of image-based SHM, which includes: (1) identifying and discovering; (2) measuring and monitoring; (3) automating and increasing efficiency; and (4) promoting development and creating 3D models. Furthermore, the responsibilities and relevance of components and parameters for implementing image-based SHM devices and systems, and their issues, are covered in this paper. Future research can benefit from the stated applications for innovation and the requirements of image-based SHM.

Unscheduled revisits to emergency departments (EDs) are important because they indicate the quality of emergency care. However, the characteristics of pediatric patients visiting EDs changed during the coronavirus disease (COVID-19) pandemic, and these changes may have affected their revisit patterns. Therefore, we aimed to compare the ED revisit patterns of pediatric patients between the pre-COVID-19 and COVID-19 periods. This retrospective multicenter study included patients aged below 18 years who visited the ED in the pre-COVID-19 and COVID-19 periods. ED revisit rates were analyzed using five age groups and three visit-revisit intervals. In the pre-COVID-19 period, the revisit rates decreased with increasing age. In the COVID-19 period, the revisit rates were the lowest for the group aged 4–6 years, and the rates increased for those aged ≥7 years. In conclusion, there were changes in the patterns of revisit rates of pediatric patients according to age between the pre-COVID-19 and COVID-19 periods. Therefore, it is necessary to identify the reasons for revisits according to age and establish strategies to reduce the revisit rates of pediatric patients.

Powerful sunlight, a high water temperature, and stagnation in the water flow induce eutrophication in rivers and lakes, which destroys the aquatic ecosystem and threatens the downstream water supply systems. Accordingly, it is very important to perform real-time measurements of nutrients that induce algal growth, especially total phosphorus, to preserve and manage the aquatic ecosystem. To conduct quantitative analysis of the total phosphorus in the aquatic ecosystem, it is essential to perform a pretreatment process and quickly separate the phosphorus, combined with organic and inorganic materials, into a phosphate. In this study, the sandblasting process was used for the physical etching of the wafer, and photocatalytic materials were deposited on the surface with various roughness in order to improve the photocatalytic reaction surface and efficiency. The photocatalytic reaction was applied to combine the pretreated sample with the coloring agent for color development, and the absorbance of the colored sample was analyzed quantitatively to compare and evaluate the characteristics, followed by the surface increase in the photocatalytic materials. In addition, the pretreatment and measurement parts were materialized in a single chip to produce a small and light total phosphorus analysis sensor.

A series of earthquake events give impetus to research on the ductile fracture behavior of steel materials. In the last decades, many fracture models have been developed and utilized in the mechanical or aerospace engineering. Nevertheless, very little application to structural members used in the construction industry has been made due to the lack of a suitable model for the fracture behavior of constructional steel. This paper presents the experimental and finite element (FE) technique to predict ductile fracture in mild carbon structural steel (SS275) sheets, which has been widely used in building structures. The post-necking true stress–strain responses were successfully estimated using the weighted-average method. The Bao and Wierzbicki (BW) model, which requires only two model parameters, was selected for the identification of fracture locus. Each model parameter was calibrated from uniaxial tension and in-plane shear specimens with the aid of digital image correlation (DIC) and finite element analysis. Fracture simulation was then performed and validated based on the experimental results of the specimens under combined tension and shear stress state.

The block shear equations specified in the current AISC specification for structural steel buildings and North American cold-formed steel design specifications are based on research results of carbon steel bolted connections. These equations were found to be inapplicable for the welded connections in the literature. This issue is primarily associated with the use of the incorrect assumption on block shear failure mechanism. The present paper examines the accuracy of various block shear equations available in the design specifications and in the literature. The paper also examines the shear hardening capacity and the level of tensile stress over the critical net area with the results of finite element analysis, in which the fracture simulation is considered. It shows that the block shear capacities of lean duplex stainless steel welded connections can be predicted accurately using tensile stress equal to 1.25Fu, as proposed in the literature.

Air pollution, particularly caused by Asian sand dust (ASD) and particulate matter (PM), has become one of the leading threats to public health. However, the majority of studies have primarily focused on epidemiological assessment, and in vivo toxicities of certain air pollutants have been poorly elucidated in medium/large-size laboratory animals. To investigate the impact of ASD in domestic animals, 16 Landrace pigs were exposed to an artificial ASD sandstorm for 6 h. All animals were divided in four cages, and a commercial yellow soil was used for generating artificial mineralogical particles. Blood samples were collected, and necropsies were performed before exposure and 6, 12, 24, and 72 h after exposure. Complete blood cell count and the levels of serum biochemical enzymes, blood gas, electrolytes, and a variety of inflammatory cytokines were evaluated. In addition, histopathological examination was conducted. Various test results proved acute lower airway disorders with systemic inflammation in pigs. To our knowledge, this study is the first to describe experimental research in domestic animals concerning the damage caused by artificial ASD exposure. The results of this study suggest that ASD has importance in terms of not only public health but also of ultimate economic losses in the pork industry.

Explosions and fire have very critical safety hazard impacts on offshore oil and gas facilities since they are mostly located in remote areas and could induce serious environmental issues. Explosion risk assessment and structure blast analysis are essential for these production facilities, and research studies have been carried out. Explosion due to blowout during drilling operation is also a critical risk for drilling units, and this has not been researched much until the accident of the drilling unit in the Gulf of Mexico in 2010. This paper provides the risk and evaluation of explosion and structure under blast pressure during the drilling operation, whereas previous research studies have mainly been interested in process plants. This study suggests weight saving in drilling units through the consideration of the actual behavior of gas explosion. Weight saving is the priority of offshore unit design due to payload. This research also gives guidelines to select the material-grade-appropriate anti-explosion system through the comparison of several materials by design and result.

Temozolomide is the current first-line treatment for glioblastoma patients but, because many patients are resistant to it, there is an urgent need to develop antitumor agents to treat temozolomide-resistant glioblastoma. Gossypol, a natural polyphenolic compound, has been studied as a monotherapy or combination therapy for the treatment of glioblastoma. The combination of gossypol and temozolomide has been shown to inhibit glioblastoma, but it is not clear yet whether gossypol alone can suppress temozolomide-resistant glioblastoma. We find that gossypol suppresses the growth of temozolomide-resistant glioblastoma cells in both tumor sphere and adherent culture conditions, with tumor spheres showing the greatest sensitivity. Molecular docking and binding energy calculations show that gossypol has a similar affinity to the Bcl2 (B-cell lymphoma 2) family of proteins and several dehydrogenases. Gossypol reduces mitochondrial membrane potential and cellular ATP levels before cell death, which suggests that gossypol inhibits several dehydrogenases in the cell’s metabolic pathway. Treatment with a Bcl2 inhibitor does not fully explain the effect of gossypol on glioblastoma. Overall, this study demonstrates that gossypol can suppress temozolomide-resistant glioblastoma and will be helpful for the refinement of gossypol treatments by elucidating some of the molecular mechanisms of gossypol in glioblastoma.

A tunable Fabry-Perot interferometer (TFPI)-type wavelength filter designed for the long-wavelength infrared (LWIR) region is fabricated using micro electro mechanical systems (MEMS) technology and the novel polydimethylsiloxane (PDMS) micro patterning technique. The structure of the proposed infrared sensor consists of a Fabry-Perot interferometer (FPI)-based optical filter and infrared (IR) detector. An amorphous Si-based thermal IR detector is located under the FPI-based optical filter to detect the IR-rays filtered by the FPI. The filtered IR wavelength is selected according to the air etalon gap between reflectors, which is defined by the thickness of the patterned PDMS. The 8 μm-thick PDMS pattern is fabricated on a 3 nm-thick Al layer used as a reflector. The air etalon gap is changed using the electromagnetic force between the permanent magnet and solenoid. The measured PDMS gap height is about 2 μm, ranging from 8 μm to 6 μm, with driving current varying from 0 mA to 600 mA, resulting in a tunable wavelength range of 4 μm. The 3-dB bandwidth (full width at half maximum, FWHM) of the proposed filter is 1.5 nm, while the Free Spectral Range (FSR) is 8 μm. Experimental results show that the proposed TFPI can detect a specific wavelength at the long LWIR region.

A thermal convection-based accelerometer was fabricated, and its characteristics were analyzed in this study. To understand the thermal convection of the accelerometer, the Grashof and Prandtl number equations were analyzed. This study conducted experiments to improve not only the sensitivity, but also the frequency band. An accelerometer with a more voluminous cavity showed better sensitivity. In addition, when the accelerometer used a gas medium with a large density and small viscosity, its sensitivity also improved. On the other hand, the accelerometer with a narrow volume cavity that used a gas medium with a small density and large thermal diffusivity displayed a larger frequency band. In particular, this paper focused on a Z-axis response to extend the performance of the accelerometer.

This paper presents a thermal convection–based sensor fabricated using simple microelectromechanical systems (MEMS)-based processes. This sensor can be applied to both acceleration and inclination measurements without modifying the structure. Because the operating mechanism of the accelerometer is the thermal convection of a gas medium, a simple model is proposed and developed in which the performance of the thermal convection–based accelerometer is closely associated with the Grashof number, Gr and the Prandtl number, Pr. This paper discusses the experiments that were performed by varying several parameters such as the heating power, cavity size, gas media, and air pressure. The experimental results demonstrate that an increase in the heating power, pressure, and cavity size leads to an increase in the accelerometer sensitivity. However, an increase in the pressure and/or cavity size results in a decrease in the frequency bandwidth. This paper also discusses the fact that a working-gas medium with a large thermal diffusivity and small kinematic viscosity can widen the frequency bandwidth and increase the sensitivity, respectively.