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Your search keyword '"Kazuya, Takehana"' showing total 2 results
Start Over Author "Kazuya, Takehana" Publisher mdpi ag
2 results on '"Kazuya, Takehana"'

1. The Correlation between the Vascular Calcification Score of the Coronary Artery and the Abdominal Aorta in Patients with Psoriasis

Author

Trang Nguyen-Mai Huynh, Fumikazu Yamazaki, Izumi Kishimoto, Akihiro Tanaka, Yonsu Son, Yoshio Ozaki, Kazuya Takehana, and Hideaki Tanizaki

Subjects
calcification, coronary artery, abdominal aorta, psoriasis, risk factors, velocity, Medicine (General), R5-920
Abstract

Psoriasis is known as an independent risk factor for cardiovascular disease due to its chronic inflammation. Studies have been conducted to evaluate the progress of atherosclerotic plaques in psoriasis. However, inadequate efforts have been made to clarify the relationship between atherosclerosis progress in coronary arteries and other important blood vessels. For that reason, we investigated the correlation and development of the coronary artery calcification score (CACS) and the abdominal aortic calcification score (AACS) during a follow-up examination. Eighty-three patients with psoriasis underwent coronary computed tomography angiography (CCTA) for total CACS and abdominal computed tomography (AbCT) for total AACS. PASI score, other clinical features, and blood samples were collected at the same time. The patients’ medical histories were also retrieved for further analysis. Linear regression was used to analyze the CACS and AACS associations. There was a moderate correlation between CACS and AACS, while both calcification scores relatively reflected the coronary plaque number, coronary stenosis number, and stenosis severity observed with CCTA. Both calcification scores were independent of the PASI score. However, a significantly higher CACS was found in psoriatic arthritis, whereas no similar phenomenon was recorded for AACS. To conclude, both CACS and AACS might be potential alternative tests to predict the presence of coronary lesions as confirmed by CCTA.

Published
2023
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2. Relationship between Psoriasis and Prevalence of Cardiovascular Disease in 88 Japanese Patients

Author

Akihiro Tanaka, Hideaki Tanizaki, Fumikazu Yamazaki, Yonsu Son, Yoshio Ozaki, and Kazuya Takehana

Subjects
medicine.medical_specialty, Univariate analysis, Multivariate analysis, business.industry, Pressure index, CCTA (coronary artery and cardiac computed tomography), General Medicine, Disease, psoriasis, medicine.disease, University hospital, Article, Psoriatic arthritis, ABI (ankle–brachial pressure index), CVD (cardiovascular disease), Psoriasis, Internal medicine, medicine, Japanese, Medicine, In patient, business
Abstract

Psoriasis is a systemic inflammatory disease known to affect survival in the presence of cerebral or cardiovascular comorbidities. However, no clear guidelines have been defined regarding the extent of vascular lesion testing that should be performed in patients with psoriasis. We therefore performed coronary computed tomography angiography (CCTA) in 88 Japanese patients with psoriasis who visited Kansai Medical University Hospital between 2015 and 2019 and determined the ankle–brachial pressure index (ABI) for 44 of these patients. CCTA abnormalities were found in 39 of the 88 patients, and a need for treatment was identified in 14 patients. The prevalence of cardiovascular lesions in these patients was 15.9%, significantly higher than that in the healthy Japanese population (6.38% according to the Suita Study). In the 44 patients with results for both ABI and CCTA, the rates of CCTA vascular lesions were significantly higher in cases with ABIs indicating hard vessels or above than in cases with supple, normal, or slightly stiff vessels. This is the first report to show a correlation between CCTA and ABI in psoriasis patients. ABI was considered useful as a preliminary test before CCTA. The univariate analysis of the abnormal and normal CCTA groups showed that the prevalence differed significantly among patients with psoriatic arthritis, erythrodermic psoriasis, older age, pre-existing conditions, drinking, and hypertension. The multivariate analysis showed correlations with arthritic or erythrodermic psoriasis.

Published
2021

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