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The microbiologically influenced corrosion of 201 stainless steel by Shewanella algae was investigated via modulating the concentration of fumarate (electron acceptor) in the medium and constructing mutant strains induced by ΔOmcA. The ICP-MS and electrochemical tests showed that the presence of S. algae enhanced the degradation of the passive film; the lack of an electron acceptor further aggravated the effect and mainly affected the early stage of MIC. The electrochemical tests and atomic force microscopy characterization revealed that the ability of ΔOmcA to transfer electrons to the passive film was significantly reduced in the absence of the c-type cytochrome OmcA related to EET progress, leading to the lower corrosion rate of the steel.

A novel plasma-pulsed GMAW hybrid welding (plasma-GMAW-P) process is proposed for joining 6061 aluminum and zinc-coated steel. The results show that the change in welding heat input has little effect on the microstructure of the joint and the composition of the intermetallic compounds (IMCs) but only changes the thickness of the reaction layer (increased from 5 μm to 12 μm). when the plasma arc current is 20 A and the MIG current is 80 A, the welded joint obtained has the highest tensile-shear force. With the optimal process parameters, the weld strength obtained by filling ER4043 welding wire is the highest, accounting for 65% of the tensile-shear force of the base material. The effect of the plasma arc acting on the joint properties is studied through the microstructure and a tensile-shearing test. The action position of the plasma arc plays a significant role in the Al/steel interface, which directly influences the strength of the welded joints. Regardless of the plasma-GMAW-P style used to obtain the joints, Fe-Al IMCs appear at the interface. When the plasma arc is in front of the welding direction and the GMAW-P arc is in the rear, the tensile-shear force reaches the maximum of 3322 N.

This paper explores the typological attributes, practical characteristics, and policy connotations of Christian social service organizations in present China. This is achieved from the perspectives of religion, public administration, social work, and history. Data collection and analysis are based on the literature research and field research methods. The main points are as follows: (1) Christian social service organizations are simultaneously faith-based organizations, legal-person organizations, and professional organizations. These different types of characteristics put forward different requirements for their service functions and performance standards. It is necessary to understand their corresponding boundaries in theory and coordinate or optimize their corresponding functions in the system; (2) Christian social service organizations present the characteristics of pluralism and transition in the practice process, as well as form complex symbiosis and embedded relationships with non-religious professional service systems. Further, they have begun to reach a consensus on industry codes of practice, service concepts, and clinical models, especially in regard to the culturally sensitive service centered on the clients; and (3) the triple-type attributes of Christian social service organizations require government departments and professional circles to direct more attention to the “matrix” of policy tools—in other words, formulate more discerning and diverse policy measures in line with policy objectives, as well as strengthen the legalization of the policy implementation mechanism and the level of collaborative governance of religious social service organizations.

DNA polymerase delta 1 catalytic subunit (POLD1) plays a vital role in genomic copy with high fidelity and DNA damage repair processes. However, the prognostic value of POLD1 and its relationship with tumor immunity in clear cell renal cell carcinoma (ccRCC) remains to be further explored. Transcriptional data sets and clinical information were obtained from the TCGA, ICGC, and GEO databases. Differentially expressed genes (DEGs) were derived from the comparison between the low and high POLD1 expression groups in the TCGA–KIRC cohort. KEGG and gene ontology (GO) analyses were performed for those DEGs to explore the potential influence of POLD1 on the biological behaviors of ccRCC. The prognostic clinical value and mutational characteristics of patients were described and analyzed according to the POLD1 expression levels. TIMER and TISIDB databases were utilized to comprehensively investigate the potential relevance between the POLD1 levels and the status of the immune cells, as well as the tumor infiltration of immune cells. In addition, RT-qPCR, Western blot, immunohistochemistry and several functional and animal experiments were performed for clinical, in vitro and in vivo validation. POLD1 was highly expressed in a variety of tumors including ccRCC, and further verified in a validation cohort of 60 ccRCC samples and in vitro cell line experiments. POLD1 expression levels in the ccRCC samples were associated with various clinical characteristics including pathologic tumor stage and histologic grade. ccRCC patients with high POLD1 expression have poor clinical outcomes and exhibit a higher rate of somatic mutations than those with low POLD1 expression. Cox regression analysis also showed that POLD1 could act as a potential independent prognostic biomarker. The DEGs associated with POLD1 were significantly enriched in the immunity-related pathways. Moreover, further immune infiltration analysis indicated that high POLD1 expression was associated with high NK CD56bright cells, Treg cells, and myeloid-derived suppressor cells’ (MDSCs) infiltration scores, as well as their marker gene sets of immune cell status. Meanwhile, POLD1 exhibited resistance to various drugs when highly expressed. Finally, the knockdown of POLD1 inhibited the proliferation and migration, and promoted the apoptosis of ccRCC cells in vitro and in vivo, as well as influenced the activation of oncogenic signaling. Our current study demonstrated that POLD1 is a potential prognostic biomarker for ccRCC patients. It might create a tumor immunosuppressive microenvironment and inhibit the susceptibility to ferroptosis leading to a poor prognosis.

Keyholes are very important to the Plasma-MIG hybrid welding process, weld formation, and quality. With the purpose of studying the effect of the main welding parameters (plasma current, MIG current, magnetic field intensity, and welding velocity) on keyhole depth and the interaction among parameter factors, the experiment was designed by the response surface method. In addition, the prediction model with keyhole depth as the response value was obtained. The model shows the important degree of influence of each factor on keyhole depth. It shows that there is an obvious interaction between plasma current and MIG current, while there is no obvious correlation between other parameters. The temperature field of the Plasma-MIG welding process under certain parameters was obtained by using Fluent software for numerical simulation, and the evolution behavior of the keyhole was analyzed. Based on the simulation results, the metal flow mode and the movement mechanism of the keyhole are described.

China’s religious social services complement the statutory welfare. Clarifying the situations and characteristics of different types of religious social services is conducive to promoting their better integration into public welfare. With the help of existing policy texts, research documents, and website data, this paper employs the thematic framework analysis method to analyze texts and documents and uses NVivo12 and SPSS26 to analyze website data. We explore the similarities and differences between contemporary Chinese Protestant social services and Buddhist social services from the perspectives of the service program, service organizations, and service resources, starting from multiple dimensions such as vertical and horizontal, similarity and difference. The main findings include the following: (a) In terms of service programs, Protestant social services are more inclusive than Buddhist social services and more public in terms of participant selection, religious environment, and the use of spiritual methods. Protestant social services are more open in terms of service value and public expression, while Buddhist social services are more localized and are politically consistent with the government. (b) In terms of service organizations, Protestant social services and Buddhist social services are based on three main types of legal persons. Protestant social services were the first to register organizational legal persons. Protestant social organizations differentiated into special service institutions and have core organizations with strong mobilization capabilities (CCC/TSPM). There is little difference between Protestant and Buddhist social services in private non-enterprise units and foundations (transparency index, business scope). (c) In terms of service resources, both Protestant and Buddhist social services rely on donations. The sources of funds for Protestant social services are more international, diversified, and market-oriented. In terms of government resource acquisition, Protestant social services actively “adapt”, while Buddhist social services passively “rely”.

In the magnetically controlled Plasma-GMAW welding process, the composite arc forms a keyhole in the workpiece to be welded. In order to explore the effect of process parameters on arc coupling, weld pool and keyhole, and the behavior characteristics of keyhole, the arc behavior and side weld pool information were collected using a welding arc acquisition system and a high-speed camera during bead-on-plate welding. The arc image is processed by pseudo-color enhancement technology, and the collected molten pool information is analyzed by boundary extraction algorithm and coordinate conversion algorithm, and the molten pool boundary and keyhole entrance width are obtained. It is found that the coupling degree of the two arcs increases with the increase in plasma current, GMAW current and magnetic field intensity. With the increase in plasma current, the size of keyhole inlet increases; with the increase of GMAW current, the size of keyhole inlet decreases, and the wave crest increases. With the increase of magnetic field intensity, the intensity of metal oscillation between the two arcs increases, and so does the wave crest.

The Q235 steel plate butt joint was successfully welded by the laser K-TIG hybrid welding method. The effects of hybrid welding process parameters such as welding current, the distance between heat sources, laser power, laser defocusing amount, and welding speed on the coupled arc profile and welding process stability were studied. The results indicated that the laser deflects the K-TIG arc, and the deflection angle becomes smaller as the arc current increases. After K-TIG generates small holes, if the laser beam acts on the bottom of the keyhole, the welded depth can be further increased; however, the laser power has little effect on the welded depth. The distance between heat sources is the main factor affecting the state of laser-arc coupling. Optical microstructures of welded joints showed that the grains in the arc zone were coarser than those in the laser zone, and there are more columnar crystals in the fusion zone. The microhardness of the weld center is significantly higher than that of the base metal, up to 220 HV. At the same time, the change of tensile strength of the weld under the influence of a single parameter was analyzed, and it was found that tensile properties of the weld first increased and then decreased with the increase of K-TIG arc current I, heat source distance D, and welding speed V, respectively. With the increase of laser power P, it first decreased and then increased, and with the increase of laser defocusing amount δf, it showed a downward trend.

The use of a Zn/Ag–Cu–Zn/Zn multi-interlayer was observed to avoid the formation of Mg–Al binary intermetallic compounds (IMCs), which cause embrittlement and low strength of bonding when dissimilar metals such as Mg/Al are joined using ultrasound-assisted transient liquid phase bonding (U-TLP). The change in the microstructure and mechanical properties of the AZ31B/LY12 joints at 410, 440, and 460 °C with prolonging ultrasonic treatment (UST) time was investigated. The results showed that the diffusion of Ag and Cu was faster into the brazing seam on the LY12 side than that on the AZ31B side with increasing UST and temperature. The IMCs on both sides of the joints were transformed with the diffusion of Ag and Cu. The transformation made the fracture path shift from the AZ31B side (410, 440 °C) to the LY12 side (460 °C), and the maximum shear strength of the joints from 43.3 (410 °C) to 65.7 (440 °C) to 84.7 MPa (460 °C). The IMCs on the surface of the fracture path corresponding to the joints with optimal mechanical properties changed from Mg7Zn3+MgZn2+α-Mg (410 °C) to MgZnCu+Mg7Zn3 (440 °C) to Al2Cu (460 °C).

This paper discusses the types, faith attributes, development characteristics, and limitations of Christian social organizations in China. China’s religious social service organizations mainly include four types of organizations: associations, private non-enterprise units, foundations, and venues for religious activities. From the perspective of faith attributes, they can be divided into faith-permeated organizations, faith-centered organizations, faith-affiliated organizations, faith-background organizations, and faith–secular partnerships. Since the reform and opening up in 1978, China’s Christian social services have been in a period of organizational reconstruction. The main development characteristics are as follows: (a) social services have begun to take on multiple forms; (b) institutional services have transferred their original focus on those with disabilities to the elderly, and the services have been gradually extended from the low-income populations to other target groups; and (c) the basic functions of social services are still in the recovery stage, and the organizational system and service scale are not complete and sufficient. The multiple limitations of Christian social services involve (a) the social development stage and institutional background; (b) government policy text and implementation; and (c) maturity of its own organizational structure and service ability. There is still a long way to go to achieve the basic goals of reconstruction and development.

In this paper, coupled with Reynolds-averaged Navier–Stokes equations and ballistic equations, the numerical simulations of high-speed water entry of projectiles under different conditions have been conducted. The water-gas flow was modeled by the mixture multiphase model. The numerical results indicated that the simulations agree well with analytical solutions by two cavity models, which validates the model applied. Then the effects of variations of project length, entry angle and velocity on the entry process of projectiles were further investigated. The results show that, for small water entry angles, the cavity wall interacts with the projectile, affects the trajectory of the projectile, and even ricochets for projectiles with small length (5D). On the other hand, the projectile vibrates during the whole process of water entry; the vibration amplitude decreases with the increase of projectile length and entry angle; however, it is the contrary for the vibration period. Furthermore, after the initial impact period, the influence of these parameters on the drag coefficient is not obvious.

The main purpose of this study was to optimize the preparation of lysozyme nanoliposomes using response surface methodology and measure their stability. The stabilities of lysozyme nanoliposomes in simulated gastrointestinal fluid (SGF), simulated intestinal fluid (SIF), as well as pH, temperature and sonication treatment time were evaluated. Reverse-phase evaporation method is an easy, speedy, and beneficial approach for nanoliposomes’ preparation and optimization. The optimal preparative conditions were as follows: phosphatidylcholine-to-cholesterol ratio of 3.86, lysozyme concentration of 1.96 mg/mL, magnetic stirring time of 40.61 min, and ultrasound time of 14.15 min. At the optimal point, encapsulation efficiency and particle size were found to be 75.36% ± 3.20% and 245.6 nm ± 5.2 nm, respectively. The lysozyme nanoliposomes demonstrated certain stability in SGF and SIF at a temperature of 37 °C for 4 h, and short sonication handling times were required to attain nano-scaled liposomes. Under conditions of high temperature, acidity and alkalinity, lysozyme nanoliposomes are unstable.