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Nuclear Protein in Testis (NUT)-rearranged tumors comprise predominantly NUT carcinoma but also include certain lymphomas, leukemias, skin appendage tumors, and sarcomas. Although histologically diverse, all are genetically identified by oncogenic rearrangement in the NUTM1 gene. Many fusion partners occur, and NSD3 is NUT carcinoma’s third most common partner. Herein, we present a case of a 26-year-old man with an NSD3::NUTM1 fusion sarcoma. The patient presented at the age of 13 months with a scalp nodule. Over the next 24 years, he experienced five local recurrences and ultimately expired of a rapidly progressive recurrence. His treatment included surgical resections, radiation, and various chemotherapies. Deceptively, the clinical presentation and histopathology aligned with a malignant peripheral nerve sheath tumor, a diagnosis rendered at initial resection with concurrence by a national soft tissue tumor expert. The patient’s exceptionally long survival could be due to NSD3 as the fusion partner, aided by the initial small tumor size and young patient age. Thus, this case expands NUT fusion sarcomas’ histologic and immunohistochemical profile to include mimicking a malignant peripheral nerve sheath tumor (MPNST). Additionally, it indicates that the NSD3::NUTM1 fusion can drive sarcoma genesis.

In the context of increasing consumption of herbivorous livestock products, competition between humans and animals for food, and increasing environmental constraints, it is necessary to solve the problem of sustainable development of China’s livestock industry and increase the protection and development of the grassland livestock industry while making good use of production resources in agricultural areas in order to explore the development potential of the herbivorous livestock industry in agricultural areas. The Converting Food Crops to Forage Crops Policy (CFFP), as an important measure of agricultural supply-side structural reform, aims to develop a high-quality forage industry and a high-quality herbivorous livestock industry. However, over the years of policy implementation, few studies have examined the impact effects of the policy on the development of the regional herbivorous livestock industry. To fill this research gap and provide theoretical support for subsequent policy implementation, the study used the synthetic control method to examine the impact of policy implementation on the development of herbivorous livestock production in the pilot counties in Hebei Province from 2010 to 2020. The study discovered that the policy’s implementation encouraged the expansion of herbivorous livestock production in the pilot counties, but the policy’s effects on various regions and livestock species varied due to the influence of local production bases and resource endowments.

The influence of tin foil and Ni coatings on microstructures, mechanical properties, and the interfacial reaction mechanism was investigated during laser welding/brazing of Al/Cu lap joints. In the presence of a Zn-based filler, tin foil as well as Ni coating strengthened the Al/Cu joints. The tin foil only slightly influenced the joint strength. It considerably improved the spreading/wetting ability of the weld filler; however, it weakened the bonding between the seam and the Al base metal. The Ni coating considerably strengthened the Al/Cu lap joints; the highest tensile strength was 171 MPa, which was higher by 15.5% than that of a joint without any interlayer. Microstructure analysis revealed that composite layers of Ni3Zn14–(τ2 Zn–Ni–Al ternary phase)–(α-Zn solid solution)–Al3Ni formed at the fusion zone (FZ)/Cu interface. Based on the inferences about the microstructures at the interfaces, thermodynamic results were calculated to analyze the interfacial reaction mechanism. The diffusion of Cu was limited by the Ni coating and the mutual attraction between the Al and Ni atoms. The microstructure comprised Zn, Ni, and Al, and they replaced the brittle Cu–Zn intermetallic compounds, successfully strengthening the bonding of the FZ/Cu interface.

Laser powder bed fusion (LPBF) of Zn-based metals exhibits prominent advantages to produce customized biodegradable implants. However, massive evaporation occurs during laser melting of Zn so that it becomes a critical issue to modulate laser energy input and gas shielding conditions to eliminate the negative effect of evaporation fume during the LPBF process. In this research, two numerical models were established to simulate the interaction between the scanning laser and Zn metal as well as the interaction between the shielding gas flow and the evaporation fume, respectively. The first model predicted the evaporation rate under different laser energy input by taking the effect of evaporation on the conservation of energy, momentum, and mass into consideration. With the evaporation rate as the input, the second model predicted the elimination effect of evaporation fume under different conditions of shielding gas flow by taking the effect of the gas circulation system including geometrical design and flow rate. In the case involving an adequate laser energy input and an optimized shielding gas flow, the evaporation fume was efficiently removed from the processing chamber during the LPBF process. Furthermore, the influence of evaporation on surface quality densification was discussed by comparing LPBF of pure Zn and a Titanium alloy. The established numerical analysis not only helps to find the adequate laser energy input and the optimized shielding gas flow for the LPBF of Zn based metal, but is also beneficial to understand the influence of evaporation on the LPBF process.