1. Antimicrobial Efficacy of Silver Nanoparticles as Root Canal Irrigant’s: A Systematic Review
- Author
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Deepak Mehta, Thodur Madapusi Balaji, Saranya Varadarajan, A. Thirumal Raj, Hitesh Chohan, Luca Testarelli, Shankargouda Patil, Jacob Thomas, Harnoor Dhillon, Mohammed Mashyakhy, and Shilpa Bhandi
- Subjects
Endodontic therapy ,medicine.medical_specialty ,silver nanoparticles ,Endodontic irrigation ,Root canal ,Dentistry ,lcsh:Medicine ,Review ,02 engineering and technology ,root canal ,Silver nanoparticle ,antimicrobials ,03 medical and health sciences ,0302 clinical medicine ,Root canal irrigant ,medicine ,irrigant ,endodontics ,business.industry ,Antimicrobial efficacy ,lcsh:R ,030206 dentistry ,General Medicine ,021001 nanoscience & nanotechnology ,Antimicrobial ,Endodontics ,medicine.anatomical_structure ,0210 nano-technology ,business - Abstract
Removal of microbes is imperative during endodontic therapy. Due to their antimicrobial property, silver nanoparticles have been used for endodontic irrigation of the root canals. The objective of the present study was to provide a qualitative analysis of the published literature assessing silver nanoparticles as root canal irrigants. A search of PubMed, SCOPUS, Web of Science, and Embase databases was done without any time restriction. Articles published in English were included. Data were extracted and the risk of bias was assessed. Of the 154 studies identified, after screening according to the inclusion criteria, five in vitro studies were included. The results indicate that silver nanoparticles have an anti-microbial effect to varying degrees depending on certain factors. Within the limitations of the present studies that have a moderate to low risk of bias, an antimicrobial effect of silver nanoparticles is observed. Silver nanoparticles have the potential to be used as endodontic irrigants, although their efficacy depends on particle size and the duration of contact which require further investigation.
- Published
- 2021