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Your search keyword '"Görbe, Anikó"' showing total 14 results
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14 results on '"Görbe, Anikó"'

1. Droplet Digital PCR Is a Novel Screening Method Identifying Potential Cardiac G-Protein-Coupled Receptors as Candidate Pharmacological Targets in a Rat Model of Pressure-Overload-Induced Cardiac Dysfunction

Author

Sayour, Nabil V., primary, Tóth, Viktória É., additional, Nagy, Regina N., additional, Vörös, Imre, additional, Gergely, Tamás G., additional, Onódi, Zsófia, additional, Nagy, Noémi, additional, Bödör, Csaba, additional, Váradi, Barnabás, additional, Ruppert, Mihály, additional, Radovits, Tamás, additional, Bleckwedel, Federico, additional, Zelarayán, Laura C., additional, Pacher, Pal, additional, Ágg, Bence, additional, Görbe, Anikó, additional, Ferdinandy, Péter, additional, and Varga, Zoltán V., additional

Published
2023
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3. Altered Cellular Protein Quality Control System Modulates Cardiomyocyte Function in Volume Overload-Induced Hypertrophy

Author

Gömöri, Kamilla, primary, Herwig, Melissa, additional, Hassoun, Roua, additional, Budde, Heidi, additional, Mostafi, Nusratul, additional, Delalat, Simin, additional, Modi, Suvasini, additional, Begovic, Merima, additional, Szabados, Tamara, additional, Pipis, Judit, additional, Farkas-Morvay, Nikolett, additional, Leprán, István, additional, Kovács, Árpád, additional, Mügge, Andreas, additional, Ferdinandy, Péter, additional, Görbe, Anikó, additional, Bencsik, Péter, additional, and Hamdani, Nazha, additional

Published
2022
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4. Rosiglitazone Does Not Show Major Hidden Cardiotoxicity in Models of Ischemia/Reperfusion but Abolishes Ischemic Preconditioning-Induced Antiarrhythmic Effects in Rats In Vivo

Author

Weber, Bennet Y., primary, Brenner, Gábor B., additional, Kiss, Bernadett, additional, Gergely, Tamás G., additional, Sayour, Nabil V., additional, Tian, Huimin, additional, Makkos, András, additional, Görbe, Anikó, additional, Ferdinandy, Péter, additional, and Giricz, Zoltán, additional

Published
2022
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6. Helium Conditioning Increases Cardiac Fibroblast Migration Which Effect Is Not Propagated via Soluble Factors or Extracellular Vesicles

Author

Jelemenský, Marek, primary, Kovácsházi, Csenger, additional, Ferenczyová, Kristína, additional, Hofbauerová, Monika, additional, Kiss, Bernadett, additional, Pállinger, Éva, additional, Kittel, Ágnes, additional, Sayour, Viktor Nabil, additional, Görbe, Anikó, additional, Pelyhe, Csilla, additional, Hambalkó, Szabolcs, additional, Kindernay, Lucia, additional, Barančík, Miroslav, additional, Ferdinandy, Péter, additional, Barteková, Monika, additional, and Giricz, Zoltán, additional

Published
2021
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8. Calcium Ionophore-Induced Extracellular Vesicles Mediate Cytoprotection against Simulated Ischemia/Reperfusion Injury in Cardiomyocyte-Derived Cell Lines by Inducing Heme Oxygenase 1

Author

Pečan, Peter, primary, Hambalkó, Szabolcs, additional, Ha, Van Thai, additional, Nagy, Csilla T., additional, Pelyhe, Csilla, additional, Lainšček, Duško, additional, Kenyeres, Bence, additional, Brenner, Gábor B., additional, Görbe, Anikó, additional, Kittel, Ágnes, additional, Barteková, Monika, additional, Ferdinandy, Péter, additional, Manček-Keber, Mateja, additional, and Giricz, Zoltán, additional

Published
2020
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10. Decorin Protects Cardiac Myocytes against Simulated Ischemia/Reperfusion Injury

Author

Gáspár, Renáta, primary, Gömöri, Kamilla, additional, Kiss, Bernadett, additional, Szántai, Ágnes, additional, Pálóczi, János, additional, Varga, Zoltán V., additional, Pipis, Judit, additional, Váradi, Barnabás, additional, Ágg, Bence, additional, Csont, Tamás, additional, Ferdinandy, Péter, additional, Barteková, Monika, additional, and Görbe, Anikó, additional

Published
2020
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13. Hidden Cardiotoxicity of Rofecoxib Can be Revealed in Experimental Models of Ischemia/Reperfusion

Author

Brenner, Gábor B., primary, Makkos, András, additional, Nagy, Csilla Terézia, additional, Onódi, Zsófia, additional, Sayour, Nabil V., additional, Gergely, Tamás G., additional, Kiss, Bernadett, additional, Görbe, Anikó, additional, Sághy, Éva, additional, Zádori, Zoltán S., additional, Lázár, Bernadette, additional, Baranyai, Tamás, additional, Varga, Richárd S., additional, Husti, Zoltán, additional, Varró, András, additional, Tóthfalusi, László, additional, Schulz, Rainer, additional, Baczkó, István, additional, Giricz, Zoltán, additional, and Ferdinandy, Péter, additional

Published
2020
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14. Identification of New, Translatable ProtectomiRs against Myocardial Ischemia/Reperfusion Injury and Oxidative Stress: The Role of MMP/Biglycan Signaling Pathways.

Author

Szabados T, Molnár A, Kenyeres É, Gömöri K, Pipis J, Pósa B, Makkos A, Ágg B, Giricz Z, Ferdinandy P, Görbe A, and Bencsik P

Abstract

Introduction: Ischemic conditionings (ICon) were intensively investigated and several protective signaling pathways were identified. Previously, we have shown the role of matrix metalloproteinases (MMP) in myocardial ischemia/reperfusion injury (MIRI) and the cardioprotective role of biglycan (BGN), a small leucine-rich proteoglycan in vitro. Here, we hypothesized that cardiac MMP and BGN signaling are involved in the protective effects of ICon., Methods: A reverse target-microRNA prediction was performed by using the miRNAtarget™ 2.0 software to identify human microRNAs with a possible regulatory effect on MMP and BGN, such as on related genes. To validate the identified 1289 miRNAs in the predicted network, we compared them to two cardioprotective miRNA omics datasets derived from pig and rat models of MIRI in the presence of ICons., Results: Among the experimentally measured miRNAs, we found 100% sequence identity to human predicted regulatory miRNAs in the case of 37 porcine and 24 rat miRNAs. Upon further analysis, 42 miRNAs were identified as MIRI-associated miRNAs, from which 24 miRNAs were counter-regulated due to ICons., Conclusions: Our findings highlight 24 miRNAs that potentially regulate cardioprotective therapeutic targets associated with MMPs and BGN in a highly translatable porcine model of acute myocardial infarction.

Published
2024
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