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7. Cytokine Response to SARS-CoV-2 Infection in Children

Author

Curatola, Antonietta, primary, Chiaretti, Antonio, additional, Ferretti, Serena, additional, Bersani, Giulia, additional, Lucchetti, Donatella, additional, Capossela, Lavinia, additional, Sgambato, Alessandro, additional, and Gatto, Antonio, additional

Published
2021
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10. Artificial Intelligence in Pediatric Emergency Medicine: Applications, Challenges, and Future Perspectives.

Author

Di Sarno L, Caroselli A, Tonin G, Graglia B, Pansini V, Causio FA, Gatto A, and Chiaretti A

Abstract

The dawn of Artificial intelligence (AI) in healthcare stands as a milestone in medical innovation. Different medical fields are heavily involved, and pediatric emergency medicine is no exception. We conducted a narrative review structured in two parts. The first part explores the theoretical principles of AI, providing all the necessary background to feel confident with these new state-of-the-art tools. The second part presents an informative analysis of AI models in pediatric emergencies. We examined PubMed and Cochrane Library from inception up to April 2024. Key applications include triage optimization, predictive models for traumatic brain injury assessment, and computerized sepsis prediction systems. In each of these domains, AI models outperformed standard methods. The main barriers to a widespread adoption include technological challenges, but also ethical issues, age-related differences in data interpretation, and the paucity of comprehensive datasets in the pediatric context. Future feasible research directions should address the validation of models through prospective datasets with more numerous sample sizes of patients. Furthermore, our analysis shows that it is essential to tailor AI algorithms to specific medical needs. This requires a close partnership between clinicians and developers. Building a shared knowledge platform is therefore a key step.

Published
2024
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