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Your search keyword '"Fangzhou Yin"' showing total 2 results
Start Over Author "Fangzhou Yin" Publisher mdpi ag
2 results on '"Fangzhou Yin"'

1. Antioxidant Properties of cis-Z,Z'-3a.7a',7a.3a'-Dihydroxy-ligustilide on Human Umbilical Vein Endothelial Cells in Vitro

Author

Xuedong Liu, Cuiping Yan, Zhipeng Chen, Baochang Cai, Ding Zhao, Fangzhou Yin, Zebin Weng, Guangming Yang, Weidong Li, Dan Liu, Yang Pan, and Yu Wu

Subjects
cis-Z,Z'-3a.7a',7a.3a'-dihydroxyligustilide, antioxidant, human umbilical vein endothelial cell, cell cycle, Organic chemistry, QD241-441
Abstract

A new chemical component, cis-Z,Z'-3a.7a',7a.3a'-dihydroxyligustilide, was isolated from Angelica sinensis and its structure elucidated from its NMR and MS spectra and confirmed by X-ray single crystal diffraction analysis. We also explored the antioxidative properties of cis-Z,Z'-3a.7a',7a.3a'-dihydroxyligustilide on human umbilical vein endothelial cells (HUVECs) against injuries induced by hydrogen peroxide (H2O2) using an MTT assay and flow cytometry analysis. In addition, the activities of superoxide dismutase (SOD), malondialdehyde (MDA), lactate dehydrogenase (LDH), nitric oxide (NO) and reactive oxygen species (ROS) were determined. We found that cis-Z,Z'-3a.7a',7a.3a'-dihydroxyligustilide increased the viability of HUVECs injured by H2O2 in a dose-dependent manner, reduced the apoptosis of HUVEC, and enhanced HUVEC proliferation. Our results demonstrated the remarkable in vitro antioxidative activities of this compound, indicating that it could be a potential antioxidant with protective effects against H2O2-induced HUVEC injuries.

Published
2013
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2. Development of a Bridge Management System Based on the Building Information Modeling Technology

Author

Zegang Yang, Yefei Xia, Zhao Xu, Chunfeng Wan, Fangzhou Yin, Siyuan Li, Zhenwei Zhou, and Youliang Ding

Subjects
Information management, Geographic information system, Computer science, Geography, Planning and Development, 0211 other engineering and technologies, TJ807-830, 020101 civil engineering, 02 engineering and technology, Management, Monitoring, Policy and Law, TD194-195, Construction engineering, Renewable energy sources, 0201 civil engineering, maintenance, 021105 building & construction, Industry Foundation Classes, management system, BIM, GE1-350, Informatization, bridge, Environmental effects of industries and plants, Renewable Energy, Sustainability and the Environment, business.industry, Environmental sciences, Building information modeling, Computerized maintenance management system, Information model, Management system, information model, business
Abstract

With the development of the Chinese transportation industry, the number of bridges has increased significantly, but this results in high pressure of structural maintenance and management. Bridge management system (BMS) is critical for efficient maintenance and ensured safety of bridge structures during long-term operation. Building information modeling (BIM) is an emerging technology with powerful visualization and informatization capability, making it an ideal tool for developing modern management systems. This paper introduces the development of a bridge management system based on the BIM technology. Industry Foundation Classes (IFC) and International Framework for Dictionaries (IFD) standards are studied and extended, and coding rules are proposed for the Chinese bridge industry. Also, a standard structural modeling method is proposed to fast build the bridge BIM model. Web-BIM oriented bridge management is proposed, and portable devices are introduced into the system. Collaborative management is realized for different users. The BIM-based maintenance management system is designed. Finally, a practical BIM-based BMS is established for a long-span cable-stayed bridge in China. This system integrates the BIM with the geographic information system (GIS) and contains information management, inspection management, technical condition evaluation, and enables users to cooperate with each other. Such a BMS could help to improve the management efficiency and ensure its normal operation, providing a useful platform for the maintenance of massive bridges in China.

Published
2019

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