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2 results on '"Ellen L. Larson"'

1. Cell-Mediated Therapies to Facilitate Operational Tolerance in Liver Transplantation

Author

Samia D. Ellias, Ellen L. Larson, Timucin Taner, and Scott L. Nyberg

Subjects
liver transplantation, transplant immunology, operational tolerance, regulatory T cells, mesenchymal cells, dendritic cells, Biology (General), QH301-705.5, Chemistry, QD1-999
Abstract

Cell therapies using immune cells or non-parenchymal cells of the liver have emerged as potential treatments to facilitate immunosuppression withdrawal and to induce operational tolerance in liver transplant (LT) recipients. Recent pre-clinical and clinical trials of cellular therapies including regulatory T cells, regulatory dendritic cells, and mesenchymal cells have shown promising results. Here we briefly summarize current concepts of cellular therapy for induction of operational tolerance in LT recipients.

Published
2021
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2. Cell-Mediated Therapies to Facilitate Operational Tolerance in Liver Transplantation

Author

Ellen L. Larson, Timucin Taner, Samia D. Ellias, and Scott L. Nyberg

Subjects
0301 basic medicine, medicine.medical_treatment, Cell, Cell- and Tissue-Based Therapy, Review, 030230 surgery, Liver transplantation, regulatory T cells, Catalysis, lcsh:Chemistry, Inorganic Chemistry, Cell therapy, 03 medical and health sciences, 0302 clinical medicine, Immune system, transplant immunology, Immune Tolerance, medicine, Humans, dendritic cells, Physical and Theoretical Chemistry, lcsh:QH301-705.5, Molecular Biology, Spectroscopy, mesenchymal cells, business.industry, Organic Chemistry, Mesenchymal stem cell, Immunosuppression, General Medicine, Cell mediated immunity, Liver Transplantation, Computer Science Applications, Clinical trial, 030104 developmental biology, medicine.anatomical_structure, lcsh:Biology (General), lcsh:QD1-999, Liver, Cancer research, Transplantation Tolerance, operational tolerance, business
Abstract

Cell therapies using immune cells or non-parenchymal cells of the liver have emerged as potential treatments to facilitate immunosuppression withdrawal and to induce operational tolerance in liver transplant (LT) recipients. Recent pre-clinical and clinical trials of cellular therapies including regulatory T cells, regulatory dendritic cells, and mesenchymal cells have shown promising results. Here we briefly summarize current concepts of cellular therapy for induction of operational tolerance in LT recipients.

Published
2021

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