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5 results on '"D'Agostino, Simona"'

1. What Does Atypical Chronic Lymphocytic Leukemia Really Mean? A Retrospective Morphological and Immunophenotypic Study

Author

D’Arena, Giovanni, primary, Vitale, Candida, additional, Pietrantuono, Giuseppe, additional, Villani, Oreste, additional, Mansueto, Giovanna, additional, D’Auria, Fiorella, additional, Statuto, Teodora, additional, D’Agostino, Simona, additional, Sabetta, Rosalaura, additional, Tarasco, Angela, additional, Innocenti, Idanna, additional, Autore, Francesco, additional, Fresa, Alberto, additional, Valvano, Luciana, additional, Tomasso, Annamaria, additional, Cafaro, Lorenzo, additional, Lamorte, Daniela, additional, and Laurenti, Luca, additional

Published
2024
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3. CD200 Baseline Serum Levels Predict Prognosis of Chronic Lymphocytic Leukemia

Author

D’Arena, Giovanni, primary, Vitale, Candida, additional, Coscia, Marta, additional, Lamorte, Daniela, additional, Pietrantuono, Giuseppe, additional, Perutelli, Francesca, additional, D’Auria, Fiorella, additional, Statuto, Teodora, additional, Valvano, Luciana, additional, Tomasso, Annamaria, additional, Griggio, Valentina, additional, Jones, Rebecca, additional, Mansueto, Giovanna, additional, Villani, Oreste, additional, D’Agostino, Simona, additional, Viglioglia, Vito, additional, De Feo, Vincenzo, additional, Calapai, Fabrizio, additional, Mannucci, Carmen, additional, Sgambato, Alessandro, additional, Efremov, Dimitar G., additional, and Laurenti, Luca, additional

Published
2021
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4. Hyperandrogenism by Liquid Chromatography Tandem Mass Spectrometry in PCOS: Focus on Testosterone and Androstenedione

Author

Grassi, Giorgia, primary, Polledri, Elisa, additional, Fustinoni, Silvia, additional, Chiodini, Iacopo, additional, Ceriotti, Ferruccio, additional, D’Agostino, Simona, additional, Filippi, Francesca, additional, Somigliana, Edgardo, additional, Mantovani, Giovanna, additional, Arosio, Maura, additional, and Morelli, Valentina, additional

Published
2020
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5. T-Large Granular Lymphocytic Leukemia with Hepatosplenic T-Cell Lymphoma? A Rare Case of Simultaneous Neoplastic T-Cell Clones Highlighted by Flow Cytometry and Review of Literature.

Author

Libonati R, Soda M, Statuto T, Valvano L, D'Auria F, D'Arena G, Pietrantuono G, Villani O, Mansueto GR, D'Agostino S, Di Somma MD, Telesca A, and Vilella R

Abstract

Lymphoproliferative diseases are a heterogeneous set of malignant clonal proliferations of lymphocytes. Despite well-established diagnostic criteria, the diagnosis remains difficult due to their variety in clinical presentation and immunophenotypic profile. Lymphoid T-cell disorders are less common than B-cell entities, and the lack of a clear immunophenotypic characteristic makes their identification hard. Flow cytometry turned out to be a useful tool in diagnosing T-cell disorders and to resolve complicated cases, especially if the number of analyzable neoplastic cells is small. We present a case of a 55-year-old man with simultaneous lymphoproliferative neoplastic T-cell clones, one αβ and the other γδ, identified and characterized by flow cytometry (FC), exploiting the variable expression intensity of specific markers. However, the patient's rapid decline made it impossible to define a differential diagnosis in order to confirm the identity of the γδ clone, which remains uncertain. This case is added to the few other cases already documented in the literature, characterized by the co-existence of T-large granular lymphocytic leukemia (T-LGLL)-αβ and T-LGLL-γδ/Hepatosplenic T-cell lymphoma (HSTCL). Our case underlines the key role of sensitive diagnostic tools in the assessment of potential relationship between the diagnosis, prognosis, and treatment in the two pathologies.

Published
2024
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