1. Recent Advances in Pancreatic Neoplasms.
- Author
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Sperti, Cosimo and Sperti, Cosimo
- Subjects
Medicine ,Oncology ,C-reactive protein to albumin ratio ,EMT ,HNF4A ,PET-CT scan ,PIWI proteins ,PIWIL3 ,PIWIL4 ,Pancreatic ductal adenocarcinoma ,biomarker ,body composition ,carbohydrate antigen 19-9 ,chemoresistance ,completion total pancreatectomy ,fluorodeoxyglucose ,inflammation ,intraductal papillary mucinous neoplasm ,low muscle mass ,microRNAs ,modified Glasgow prognostic score ,motility ,n/a ,neoadjuvant chemotherapy ,neuropathy ,neutrophyl lymphocite ratio ,pancreas ,pancreatectomy ,pancreatic adenocarcinoma ,pancreatic cancer ,pancreatic cancer prognosis ,pancreatic ductal adenocarcinoma ,pancreatic fistula ,pancreatic neoplasm ,pancreatic neoplasms ,pancreatic neuroendocrine neoplasm ,pancreatic surgery ,pancreato-gastrostomy ,platelet-to-lymphocyte ratio ,pooled analysis ,positron emission tomography ,primary pancreatic carcinoid ,prognosis ,recurrent pancreatic cancer ,renal cell carcinoma ,repeated pancreatectomy ,response ,robotic pancreatic surgery ,sarcopenia ,serotonin-producing pancreatic tumour ,serotonin-secreting pancreatic tumour ,standardized uptake value ,survival ,taxanes - Abstract
Summary: Pancreatic neoplasms include different pathological entities with variable biological behavior and different treatment modalities. Surgery and adjuvant therapy are the cornerstones of the therapeutic approach; however, even after radical resection, the majority of patients experience disease recurrence and the prognosis of pancreatic cancer remains dismal. A multimodal therapeutic approach, based on a combination of neoadjuvant therapy, chemotherapy, radiotherapy, immunotherapy and surgery, appears fundamental to improving the outcomes. This Special Issue of the Journal of Clinical Medicine, entitled "Recent Advances in Pancreatic Neoplasms", focuses on possible new strategies to treat pancreatic neoplasms.