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Understanding changes in runoff due to climate variations in glacier-dominated headwaters is key to managing water resources and dryland watersheds effectively and rationally. The continuous glacier shrinkage caused by climate warming has significantly impacted the water supply and ecological systems in the vast arid regions of Central Asia, attracting extensive public concern. The study results indicate an increase in total runoff at the Urumqi River source region during both the baseline (1997–2016) and mid-century (2040–2059) periods, encompassing rain, glacier meltwater, and snowmelt components. Compared to the baseline period, the temperature increases by the mid-century under the three climate scenarios (SSP1−26, SSP2−45, and SSP5−85) range from 0.98 to 1.48 °C. In this region, during the period from 1997 to 2016, glacier meltwater was the dominant component of runoff, comprising 42.10–43.79% of the total, followed by snowmelt at 29.64–30.40% and rainfall contributions of 26.56–27.49%. Additionally, glacier storage in this typical catchment responds quickly to temperature fluctuations, significantly impacting runoff. The Urumqi River source region's runoff exhibits heightened sensitivity to these temperature shifts compared to precipitation effects. We hypothesized three glacier coverage scenarios: unchanged at 100% glaciation, reduced by half to 50%, and fully retreated to 0% glaciation. Analysis of these scenarios demonstrated that glaciers are pivotal in runoff formation. Under the SSP1−26, SSP2−45, and SSP5−85 climate scenarios, glaciers contributed additional runoff increases of 51.61%, 57.64%, and 62.07%, respectively. Generally, glaciers play a critical role in supplying water in dry areas. Thus, accurately forecasting future water resource shifts in high-altitude glacier regions is crucial for downstream water resource management and utilization. [ABSTRACT FROM AUTHOR]

As a heavily glaciated region, the Eastern Pamir plays a crucial role in regional water supply. However, considerable ambiguity surrounds the distribution of glacier ice thickness and the details of ice volume. Accurate data at the local scale are largely insufficient. In this study, ground-penetrating radar (GPR) was applied to assess the ice thickness at Muztagh Glacier No.16 (MG16) in Muztagh Ata, Eastern Pamir, for the first time, detailing findings from four distinct profiles, bridging the gap in regional measurements. We utilized a total of five different methods based on basic shear stress, surface velocity, and mass conservation, aimed at accurately delineating the ice volume and distribution for MG16. Verification was conducted using measured data, and an aggregated model outcome provided a unified view of ice distribution. The different models showed good agreement with the measurements, but there were differences in the unmeasured areas. The composite findings indicated the maximum ice thickness of MG16 stands at 115.87 ± 4.55 m, with an ice volume calculated at 0.27 ± 0.04 km3. This result is relatively low compared to the findings of other studies, which lies in the fact that the GPR measurements somewhat constrain the model. However, the model parameters remain the primary source of uncertainty. The results from this study can be used to enhance water resource assessments for future glacier change models. [ABSTRACT FROM AUTHOR]

Two undescribed p-terphenyl derivatives, asperterphenylcins A–B (1–2), and two undescribed diphenyl ether derivatives, asperdiphenylcins A–B (3–4), together with three previously described p-terphenyl derivatives—4″-deoxyterprenin (5), terphenyllin (6), and 3″-hydroxyterphenyllin (7)—were obtained from the solid-rice culture of the marine-derived fungus Aspergillus candidus HM5-4, which was isolated from sponges from the South China Sea. Their structures were elucidated by HRESIMS data and NMR spectroscopic analysis. Compound 1 showed a strong inhibitory effect on Neoscytalidium dimidiatum, with an inhibition circle diameter of 31.67 ± 2.36 mm at a concentration of 10.0 µg/disc. Compounds 5 and 7 displayed cytotoxic activity against human chronic myeloid leukemia cells (K562), human liver cancer cells (BEL-7402), human gastric cancer cells (SGC-7901), human non-small cell lung cancer cells (A549) and human HeLa cervical cancer cells, with IC50 values ranging from 3.32 to 60.36 µM, respectively. Compounds 2, 6 and 7 showed potent inhibitory activity against α-glucosidase, with IC50 values of 1.26 ± 0.19, 2.16 ± 0.44 and 13.22 ± 0.55 µM, respectively. [ABSTRACT FROM AUTHOR]

As a particular type of alpine glacier, debris-covered glaciers are essential for local water resources and glacial disaster warnings. The Eastern Tomur Peak Region (EPTR) is the most concentrated glacier in Tien Shan Mountain, China, where the glaciers have not been studied in detail. This paper evaluates the delineation accuracy of Landsat8 OLI, Sentinel-1A, and GF images for debris-covered glaciers in the EPTR. Each image uses the most advanced delineation method for itself to minimize the error of inherent resolutions. The results show that the accuracy of these images for delineating debris-covered glaciers is very high, and the F1 scores are expressed as 96.73%, 93.55%, and 95.81%, respectively. Therefore, Landsat images were selected to analyze the area change of EPTR from 2000 to 2022 over a 5-year time scale. The results indicate that glaciers of the EPTR decreased by 19.05 km2 from 2000 to 2020, accounting for 1.9% (0.08% a−1), and debris increased by 10.8%, which validates the opinion that the presence of debris inhibits glacier melting. The most varied time was 2010–2022, but it was much less than other Tien Shan regions. The lower glacier ablation rate in this area results from the combined effect of decreased bare ice and increased debris. The main reason for the change in debris-covered glaciers is the increase in temperature. [ABSTRACT FROM AUTHOR]

The cytoplasmic male sterility (CMS) and nuclear-controlled fertility restoration system is a favorable tool for the utilization of heterosis in plant hybrid breeding. Many restorer-of-fertility (Rf) genes have been characterized in various species over the decades, but more detailed work is needed to investigate the fertility restoration mechanism. Here, we identified an alpha subunit of mitochondrial processing peptidase (MPPA) that is involved in the fertility restoration process in Honglian-CMS rice. MPPA is a mitochondrial localized protein and interacted with the RF6 protein encoded by the Rf6. MPPA indirectly interacted with hexokinase 6, namely another partner of RF6, to form a protein complex with the same molecular weight as the mitochondrial F1F0-ATP synthase in processing the CMS transcript. Loss-of-function of MPPA resulted in a defect in pollen fertility, the mppa+/− heterozygotes showed semi-sterility phenotype and the accumulation of CMS-associated protein ORFH79, showing restrained processing of the CMS-associated atp6-OrfH79 in the mutant plant. Taken together, these results threw new light on the process of fertility restoration by investigating the RF6 fertility restoration complex. They also reveal the connections between signal peptide cleavage and the fertility restoration process in Honglian-CMS rice. [ABSTRACT FROM AUTHOR]

Three new phenolic compounds, epicocconigrones C–D (1–2) and flavimycin C (3), together with six known phenolic compounds: epicocconigrone A (4); 2-(10-formyl-11,13-dihydroxy-12-methoxy-14-methyl)-6,7-dihydroxy-5-methyl-4-benzofurancarboxaldehyde (5); epicoccolide B (6); eleganketal A (7); 1,3-dihydro-5-methoxy-7-methylisobenzofuran (8); and 2,3,4-trihydroxy-6-(hydroxymethyl)-5-methylbenzyl-alcohol (9), were isolated from fermentation cultures of a deep-sea sediment-derived fungus, Aspergillus insulicola. Their planar structures were elucidated based on the 1D and 2D NMR spectra and HRESIMS data. The absolute configurations of compounds 1–3 were determined by ECD calculations. Compound 3 represented a rare fully symmetrical isobenzofuran dimer. All compounds were evaluated for their α-glucosidase inhibitory activity, and compounds 1, 4–7, and 9 exhibited more potent α-glucosidase inhibitory effect with IC50 values ranging from 17.04 to 292.47 μM than positive control acarbose with IC50 value of 822.97 μM, indicating that these phenolic compounds could be promising lead compounds of new hypoglycemic drugs. [ABSTRACT FROM AUTHOR]

Nine new azaphilones, including penicilazaphilones I–N (1, 2 and 6–9), epi-geumsanol D (3) and penidioxolanes C (4) and D (5) were isolated from the culture of the marine-derived fungus Penicillium sclerotiorum E23Y-1A. The structures of the isolates were deduced from extensive spectroscopic data (1D and 2D NMR), high-resolution electrospray ionization mass spectrometry (HRESIMS), and electronic circular dichroism (ECD) calculations. All the azaphilones from P. sclerotiorum E23Y-1A were tested for their anti-inflammatory and antitumor activities. Penicilazaphilone N (9) showed moderate anti-inflammatory activity with an IC50 value of 22.63 ± 2.95 μM, whereas penidioxolane C (4) exhibited moderate inhibition against human myeloid leukemia cells (K562), human liver cancer cells (BEL-7402), human gastric cancer cells (SGC-7901), human non-small cell lung cancer cells (A549), and human hela cervical cancer cells, with IC50 values of 23.94 ± 0.11, 60.66 ± 0.13, 46.17 ± 0.17, 60.16 ± 0.26, and 59.30 ± 0.60 μM, respectively. [ABSTRACT FROM AUTHOR]

Two years of observational data from the 532 nm Rayleigh lidar were used to study the vertical profile characteristics of atmospheric gravity wave potential energy density (GWPED) between 40–80 km above Jiuquan (40° N, 95° E) for the first time. The atmospheric gravity waves (AGWs) characteristics are presented in terms of the atmospheric relative temperature perturbation, along with the estimated annual and seasonal GWPED with high spatial and temporal resolution (0.5 km and 1 h). The annual potential energy mass density E pm and volume density E pv vertical profiles show that the GWPED in the upper mesosphere is close to the adiabatic growth rate. The seasonal vertical profiles result shows that E pm is higher in autumn–winter than in spring–summer in all the observed altitudes. The GWPED approaches adiabatic growth above 61 and 65 km in spring–summer and autumn–winter, respectively. The AGWs severely dissipate below the turning altitudes and transfer energy into the background atmosphere. The GWPED scale heights show that the AGWs dissipation rate of spring–summer is close to that of autumn–winter. Furthermore, based on the wind data from SD–WACCM, the influence of critical level filtering on AGWs is discussed. It plays an important role in affecting the seasonal variation in GWPED. [ABSTRACT FROM AUTHOR]

Rayleigh lidar data in 2013–2015 is used to describe the characteristics of gravity wave potential energy density in the mesosphere above Golmud (36.25° N, 94.54° E) of the Tibetan Plateau. In this study, the vertical profiles of the atmospheric gravity wave potential energy density between 50–80 km above the region are presented, including the potential energy mass density E pm and the potential energy volume density E pv . It shows the mathematical characteristics of the atmospheric gravity wave potential energy density vertical distribution, which also indicate the gravity waves are obviously dissipated in the lower mesosphere and close to conservative growth in the upper mesosphere (the turning point is around 61 km). A total of 1174 h of data covers seasonal changes, which reveals the seasonal characteristics of the potential energy density. The E pm increases faster with altitude in summer than others. All seasons of the potential energy density profiles show that gravity waves are dissipated in the lower mesosphere, among which spring and winter are the most severe and summer is weakest. The E pm is higher in spring and winter below 55 km. Above 55 km, it is the maximum in winter, followed by summer. Then, the AGWs activities between the location with mid–latitudes and different longitudes are compared and discussed. [ABSTRACT FROM AUTHOR]

As a sessile organism, rice often faces various kinds of abiotic stresses, such as drought stress. Drought stress seriously harms plant growth and damages crop yield every year. Therefore, it is urgent to elucidate the mechanisms of drought resistance in rice. In this study, we identified a glycine-rich RNA-binding protein, OsGRP3, in rice. Evolutionary analysis showed that it was closely related to OsGR-RBP4, which was involved in various abiotic stresses. The expression of OsGRP3 was shown to be induced by several abiotic stress treatments and phytohormone treatments. Then, the drought tolerance tests of transgenic plants confirmed that OsGRP3 enhanced drought resistance in rice. Meanwhile, the yeast two-hybrid assay, bimolecular luminescence complementation assay and bimolecular fluorescence complementation assay demonstrated that OsGRP3 bound with itself may affect the RNA chaperone function. Subsequently, the RNA-seq analysis, physiological experiments and histochemical staining showed that OsGRP3 influenced the phenylpropanoid biosynthesis pathway and further modulated lignin accumulation. Herein, our findings suggested that OsGRP3 enhanced drought resistance in rice by altering the phenylpropanoid biosynthesis pathway and further increasing lignin accumulation. [ABSTRACT FROM AUTHOR]

Accurate prediction of substation project cost is helpful to improve the investment management and sustainability. It is also directly related to the economy of substation project. Ensemble Empirical Mode Decomposition (EEMD) can decompose variables with non-stationary sequence signals into significant regularity and periodicity, which is helpful in improving the accuracy of prediction model. Adding the Gauss perturbation to the traditional Cuckoo Search (CS) algorithm can improve the searching vigor and precision of CS algorithm. Thus, the parameters and kernel functions of Support Vector Machines (SVM) model are optimized. By comparing the prediction results with other models, this model has higher prediction accuracy. [ABSTRACT FROM AUTHOR]

In the Benxi Formation of the Carboniferous system of the Upper Paleozoic in the Ordos Basin, there are many sets of coal measures dark organic-rich shale, being marine continental transitional facies, with significant unconventional natural gas potential. Previous studies are only limited to the evaluation of tight sandstone reservoir in this set of strata, with no sufficient study on gas bearing and geological characteristics of organic-rich shale, restricting the exploration and evaluation of shale gas resources. In this study, analysis has been conducted on the organic carbon content, the major elements, the trace elements, and the mineral composition of core samples from the Benxi Formation in key drilling sections. In addition, qualitative and quantitative pore observation and characterization of core samples have been conducted. The sedimentary environments and reservoir characteristics of the shale of the Benxi Formation have been analyzed. Combined with the gas content analyzing the results of the field coring samples, the shale gas resource potentials of the Benxi Formation have been studied, and the geological characteristics of the Benxi Formation shale gas in the eastern Ordos Basin have been made clear, to provide a theoretical basis for shale gas resource evaluation of the Benxi Formation in the Ordos Basin. The results show that (1) in the Hutian Member, Pangou Member, and Jinci Member of the Benxi Formation, organic-rich shale is well developed, with the characteristics of seawater input as a whole. There is a slight difference in sedimentary redox index, which shows that the reducibility increases gradually from bottom to top. (2) There is an evident difference in the mineral characteristics of shale in these three members. The Hutian Member is rich in clay minerals, while the Jinci Member is high in quartz minerals. (3) The pores are mainly inorganic mineral intergranular pores, clay interlayer fractures, and micro fractures, and organic matter pores are developed on the surface of local organic matter. (4) The mud shale in the Jinci Member has a large cumulative thickness, has relatively high gas-bearing property, and is rich in brittle minerals. The Jinci Member is a favorable section for shale gas exploration of the Benxi Formation. [ABSTRACT FROM AUTHOR]

Two undescribed p -terphenyl derivatives, asperterphenylcins A-B ( 1 - 2 ), and two undescribed diphenyl ether derivatives, asperdiphenylcins A-B ( 3 - 4 ), together with three previously described p -terphenyl derivatives-4″-deoxyterprenin ( 5 ), terphenyllin ( 6 ), and 3″-hydroxyterphenyllin ( 7 )-were obtained from the solid-rice culture of the marine-derived fungus Aspergillus candidus HM5-4, which was isolated from sponges from the South China Sea. Their structures were elucidated by HRESIMS data and NMR spectroscopic analysis. Compound 1 showed a strong inhibitory effect on Neoscytalidium dimidiatum , with an inhibition circle diameter of 31.67 ± 2.36 mm at a concentration of 10.0 µg/disc. Compounds 5 and 7 displayed cytotoxic activity against human chronic myeloid leukemia cells (K562), human liver cancer cells (BEL-7402), human gastric cancer cells (SGC-7901), human non-small cell lung cancer cells (A549) and human HeLa cervical cancer cells, with IC 50 values ranging from 3.32 to 60.36 µM, respectively. Compounds 2 , 6 and 7 showed potent inhibitory activity against α -glucosidase, with IC 50 values of 1.26 ± 0.19, 2.16 ± 0.44 and 13.22 ± 0.55 µM, respectively.