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Geospatial data, especially remote sensing (RS) data, are of significant importance for public services and production activities. Expertise is critical in processing raw data, generating geospatial information, and acquiring domain knowledge and other remote sensing applications. However, existing geospatial service platforms are more oriented towards the professional users in the implementation process and final application. Building appropriate geographic applications for non-professionals remains a challenge. In this study, a geospatial data service architecture is designed that links desktop geographic information system (GIS) software and cloud-based platforms to construct an efficient user collaboration platform. Based on the scalability of the platform, four web apps with different themes are developed. Data in the fields of ecology, oceanography, and geology are uploaded to the platform by the users. In this pilot phase, the gap between non-specialized users and experts is successfully bridged, demonstrating the platform's powerful interactivity and visualization. The paper finally evaluates the capability of building spatial data infrastructures (SDI) based on GeoNode and discusses the current limitations. The support for three-dimensional data, the improvement of metadata creation and management, and the fostering of an open geo-community are the next steps. [ABSTRACT FROM AUTHOR]

Corona Virus Disease 2019 (COVID-19) not only causes respiratory system damage, but also imposes strain on the cardiovascular system. Vascular endothelial cells and cardiomyocytes play an important role in cardiac function. The aberrant expression of genes in vascular endothelial cells and cardiomyocytes can lead to cardiovascular diseases. In this study, we sought to explain the influence of respiratory syndrome coronavirus 2 (SARS-CoV-2) infection on the gene expression levels of vascular endothelial cells and cardiomyocytes. We designed an advanced machine learning-based workflow to analyze the gene expression profile data of vascular endothelial cells and cardiomyocytes from patients with COVID-19 and healthy controls. An incremental feature selection method with a decision tree was used in building efficient classifiers and summarizing quantitative classification genes and rules. Some key genes, such as MALAT1, MT-CO1, and CD36, were extracted, which exert important effects on cardiac function, from the gene expression matrix of 104,182 cardiomyocytes, including 12,007 cells from patients with COVID-19 and 92,175 cells from healthy controls, and 22,438 vascular endothelial cells, including 10,812 cells from patients with COVID-19 and 11,626 cells from healthy controls. The findings reported in this study may provide insights into the effect of COVID-19 on cardiac cells and further explain the pathogenesis of COVID-19, and they may facilitate the identification of potential therapeutic targets. [ABSTRACT FROM AUTHOR]

The morphological characteristics of yardangs are the direct evidence that reveals the wind and fluvial erosion for lacustrine sediments in arid areas. These features can be critical indicators in reconstructing local wind directions and environment conditions. Thus, the fast and accurate extraction of yardangs is key to studying their regional distribution and evolution process. However, the existing automated methods to characterize yardangs are of limited generalization that may only be feasible for specific types of yardangs in certain areas. Deep learning methods, which are superior in representation learning, provide potential solutions for mapping yardangs with complex and variable features. In this study, we apply Mask region-based convolutional neural networks (Mask R-CNN) to automatically delineate and classify yardangs using very high spatial resolution images from Google Earth. The yardang field in the Qaidam Basin, northwestern China is selected to conduct the experiments and the method yields mean average precisions of 0.869 and 0.671 for intersection of union (IoU) thresholds of 0.5 and 0.75, respectively. The manual validation results on images of additional study sites show an overall detection accuracy of 74%, while more than 90% of the detected yardangs can be correctly classified and delineated. We then conclude that Mask R-CNN is a robust model to characterize multi-scale yardangs of various types and allows for the research of the morphological and evolutionary aspects of aeolian landform. [ABSTRACT FROM AUTHOR]