1. Fluorescence Resonance Energy Transfer Systems in Supramolecular Macrocyclic Chemistry
- Author
-
Nan Song, Xin-Yue Lou, and Ying-Wei Yang
- Subjects
Macrocyclic Compounds ,Chemical Phenomena ,Supramolecular chemistry ,Pharmaceutical Science ,Nanotechnology ,Review ,Biosensing Techniques ,010402 general chemistry ,Smart material ,01 natural sciences ,supramolecular chemistry ,Analytical Chemistry ,lcsh:QD241-441 ,Drug Delivery Systems ,lcsh:Organic chemistry ,Cucurbituril ,Optical materials ,Drug Discovery ,Fluorescence Resonance Energy Transfer ,host-guest chemistry ,Physical and Theoretical Chemistry ,Host–guest chemistry ,Molecular Structure ,010405 organic chemistry ,Chemistry ,Organic Chemistry ,Responsive systems ,pillararene ,Pillararene ,0104 chemical sciences ,cucurbituril ,Förster resonance energy transfer ,Nanomedicine ,cyclodextrin ,Models, Chemical ,Chemistry (miscellaneous) ,Molecular Medicine ,calixarene ,Nanoparticles - Abstract
The fabrication of smart materials is gradually becoming a research focus in nanotechnology and materials science. An important criterion of smart materials is the capacity of stimuli-responsiveness, while another lies in selective recognition. Accordingly, supramolecular host-guest chemistry has proven a promising support for building intelligent, responsive systems; hence, synthetic macrocyclic hosts, such as calixarenes, cucurbiturils, cyclodextrins, and pillararenes, have been used as ideal building blocks. Meanwhile, manipulating and harnessing light artificially is always an intensive attempt for scientists in order to meet the urgent demands of technological developments. Fluorescence resonance energy transfer (FRET), known as a well-studied luminescent activity and also a powerful tool in spectroscopic area, has been investigated from various facets, of which the application range has been broadly expanded. In this review, the innovative collaboration between FRET and supramolecular macrocyclic chemistry will be presented and depicted with typical examples. Facilitated by the dynamic features of supramolecular macrocyclic motifs, a large variety of FRET systems have been designed and organized, resulting in promising optical materials with potential for applications in protein assembly, enzyme assays, diagnosis, drug delivery monitoring, sensing, photosynthesis mimicking and chemical encryption.
- Published
- 2017