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3 results on '"Wencheng Wang"'

1. Correction: Wu, H.; et al. A Purified Aspartic Protease from Akkermansia Muciniphila Plays an Important Role in Degrading Muc2. Int. J. Mol. Sci. 2020, 21, 72

Author

Hao Wu, Xin Meng, Wanxin Yang, Wencheng Wang, Dahai Yu, Tianqi Lan, and Xuexun Fang

Subjects
Aspartic Acid Proteases, Catalysis, Inorganic Chemistry, lcsh:Chemistry, Aspartate protease, Bacterial Proteins, Verrucomicrobia, Cell Line, Tumor, Animals, Humans, Physical and Theoretical Chemistry, Molecular Biology, lcsh:QH301-705.5, Spectroscopy, Mice, Inbred BALB C, Mucin-2, biology, Chemistry, Organic Chemistry, INT, Correction, General Medicine, Akkermansia, biology.organism_classification, Computer Science Applications, n/a, Biochemistry, lcsh:Biology (General), lcsh:QD1-999, Proteolysis, Akkermansia muciniphila, HeLa Cells
Abstract

The authors wish to make the following corrections to this paper [...]

Published
2021

2. Application of Carbon-Microsphere-Modified Electrodes for Electrochemistry of Hemoglobin and Electrocatalytic Sensing of Trichloroacetic Acid

Author

Fan Shi, Xueliang Niu, Lijun Yan, Guo-Lei Huang, Wencheng Wang, Cai-Juan Zheng, and Wei Sun

Subjects
Working electrode, Inorganic chemistry, chemistry.chemical_element, direct electrochemistry, Biosensing Techniques, Electrochemistry, lcsh:Chemical technology, Biochemistry, Sensitivity and Specificity, Article, Analytical Chemistry, chemistry.chemical_compound, Hemoglobins, trichloroacetic acid, lcsh:TP1-1185, Electrical and Electronic Engineering, Trichloroacetic acid, Instrumentation, Electrodes, health care economics and organizations, Detection limit, Chemistry, Reproducibility of Results, Electrochemical Techniques, hemoglobin, carbon microsphere, Atomic and Molecular Physics, and Optics, Carbon, Microspheres, Anode, Immobilized Proteins, Linear range, Electrode, Linear Models
Abstract

By using the hydrothermal method, carbon microspheres (CMS) were fabricated and used for electrode modification. The characteristics of CMS were investigated using various techniques. The biocompatible sensing platform was built by immobilizing hemoglobin (Hb) on the micrometer-sized CMS-modified electrode with a layer of chitosan membrane. On the cyclic voltammogram, a couple of quasi-reversible cathodic and anodic peaks appeared, showing that direct electrochemistry of Hb with the working electrode was achieved. The catalytic reduction peak currents of the bioelectrode to trichloroacetic acid was established in the linear range of 2.0~70.0 mmol·L(-1) accompanied by a detection limit of 0.30 mmol·L(-1) (3σ). The modified electrode displayed favorable sensitivity, good reproducibility and stability, which suggests that CMS is promising for fabricating third-generation bioelectrochemical sensors.

Published
2015

3. The Roles of Reactive Oxygen Species and Nitric Oxide in Perfluorooctanoic Acid-Induced Developmental Cardiotoxicity and L-Carnitine Mediated Protection.

Author

Meng Zhao, Qixiao Jiang, Wencheng Wang, Min Geng, Meng Wang, Yantao Han, and Chunbo Wang

Subjects
PERFLUOROOCTANOIC acid, REACTIVE oxygen species, NITRIC oxide, CARDIOTOXICITY, ELECTRON paramagnetic resonance
Abstract

Perfluorooctanoic acid (PFOA) is an environmental contaminant that could induce developmental cardiotoxicity in a chicken embryo, which may be alleviated by L-carnitine. To explore the roles of reactive oxygen species (ROS) and nitric oxide (NO) in such changes and the potential effects of L-carnitine, fertile chicken eggs were exposed to PFOA via an air cell injection, with or without L-carnitine co-treatment. The ROS and NO levels in chicken embryo hearts were determined with electron spin resonance (ESR), and the protein levels of the nuclear factor κ-light chain-enhancer of activated B cells (NF-κB) p65 and inducible nitric oxide synthase (iNOS) in chicken embryo hearts were assessed with western blotting. The results of ESR indicated that PFOA exposure induced an elevation in the ROS levels in ED19 chicken embryo hearts and hatchling chicken hearts, while L-carnitine could alleviate such changes. Meanwhile, increased NO levels were observed in ED19 embryo hearts and hatchling hearts following PFOA exposure, while L-carnitine co-treatment exerted modulatory effects. Western blotting revealed that p65 translocation in ED19 embryo hearts and hatchling hearts was enhanced by PFOA, while L-carnitine co-treatment alleviated such changes. iNOS expression levels in ED19 embryo hearts followed the same pattern as NO levels, while a suppression of expression was observed in hatchling hearts exposed to PFOA. ROS/NF-κB p65 and iNOS/NO seem to be involved in the late stage (ED19 and post hatch) of PFOA-induced developmental cardiotoxicity in a chicken embryo. L-carnitine could exert anti-oxidant and NO modulatory effects in the developing chicken embryo hearts, which likely contribute to its cardioprotective effects. [ABSTRACT FROM AUTHOR]

Published
2017
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