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The incorporation of automatic segmentation methodologies into dental X-ray images refined the paradigms of clinical diagnostics and therapeutic planning by facilitating meticulous, pixel-level articulation of both dental structures and proximate tissues. This underpins the pillars of early pathological detection and meticulous disease progression monitoring. Nonetheless, conventional segmentation frameworks often encounter significant setbacks attributable to the intrinsic limitations of X-ray imaging, including compromised image fidelity, obscured delineation of structural boundaries, and the intricate anatomical structures of dental constituents such as pulp, enamel, and dentin. To surmount these impediments, we propose the Deformable Convolution and Mamba Integration Network, an innovative 2D dental X-ray image segmentation architecture, which amalgamates a Coalescent Structural Deformable Encoder, a Cognitively-Optimized Semantic Enhance Module, and a Hierarchical Convergence Decoder. Collectively, these components bolster the management of multi-scale global features, fortify the stability of feature representation, and refine the amalgamation of feature vectors. A comparative assessment against 14 baselines underscores its efficacy, registering a 0.95% enhancement in the Dice Coefficient and a diminution of the 95th percentile Hausdorff Distance to 7.494. [ABSTRACT FROM AUTHOR]

In the field of collaborative filtering, attribute information is often integrated to improve recommendations. However, challenges remain unaddressed. Firstly, existing data modeling methods often fall short of appropriately handling attribute information. Secondly, attribute data are often sparse and can potentially impact recommendation performance due to the challenge of incomplete correspondence between the attribute information and the recommendations. To tackle these challenges, we propose a hypergraph collaborative filtering with attribute inference (HCFA) framework, which segregates attribute and user behavior information into distinct channels and leverages hypergraphs to capture high-order correlations among vertices, offering a more natural approach to modeling. Furthermore, we introduce behavior-based attribute confidence (BAC) for assessing the reliability of inferred attributes concerning the corresponding behaviors and update the most credible portions to enhance recommendation quality. Extensive experiments conducted on three public benchmarks demonstrate the superiority of our model. It consistently outperforms other state-of-the-art approaches, with ablation experiments further confirming the effectiveness of our proposed method. [ABSTRACT FROM AUTHOR]

Optical coherence tomography angiography (OCTA) offers critical insights into the retinal vascular system, yet its full potential is hindered by challenges in precise image segmentation. Current methodologies struggle with imaging artifacts and clarity issues, particularly under low-light conditions and when using various high-speed CMOS sensors. These challenges are particularly pronounced when diagnosing and classifying diseases such as branch vein occlusion (BVO). To address these issues, we have developed a novel network based on topological structure generation, which transitions from superficial to deep retinal layers to enhance OCTA segmentation accuracy. Our approach not only demonstrates improved performance through qualitative visual comparisons and quantitative metric analyses but also effectively mitigates artifacts caused by low-light OCTA, resulting in reduced noise and enhanced clarity of the images. Furthermore, our system introduces a structured methodology for classifying BVO diseases, bridging a critical gap in this field. The primary aim of these advancements is to elevate the quality of OCTA images and bolster the reliability of their segmentation. Initial evaluations suggest that our method holds promise for establishing robust, fine-grained standards in OCTA vascular segmentation and analysis. [ABSTRACT FROM AUTHOR]

RGB-T salient object detection (SOD) has made significant progress in recent years. However, most existing works are based on heavy models, which are not applicable to mobile devices. Additionally, there is still room for improvement in the design of cross-modal feature fusion and cross-level feature fusion. To address these issues, we propose a lightweight cross-modal information mutual reinforcement network for RGB-T SOD. Our network consists of a lightweight encoder, the cross-modal information mutual reinforcement (CMIMR) module, and the semantic-information-guided fusion (SIGF) module. To reduce the computational cost and the number of parameters, we employ the lightweight module in both the encoder and decoder. Furthermore, to fuse the complementary information between two-modal features, we design the CMIMR module to enhance the two-modal features. This module effectively refines the two-modal features by absorbing previous-level semantic information and inter-modal complementary information. In addition, to fuse the cross-level feature and detect multiscale salient objects, we design the SIGF module, which effectively suppresses the background noisy information in low-level features and extracts multiscale information. We conduct extensive experiments on three RGB-T datasets, and our method achieves competitive performance compared to the other 15 state-of-the-art methods. [ABSTRACT FROM AUTHOR]

Deep learning-based image compression techniques can take advantage of the autoencoder's benefits to achieve greater compression quality at the same bit rate as traditional image compression, which is more in line with user desires. Designing a high-performance processor that can increase the inference speed and efficiency of the deep learning image compression (DIC) network is important to make this technology more extensively employed in mobile devices. To the best of our knowledge, there is no dedicated processor that can accelerate DIC with low power consumption, and general-purpose network accelerators based on field programmable gate arrays (FPGA) cannot directly process compressed networks, so we propose a processor suitable for DIC in this paper. First, we analyze the image compression algorithm and quantize the data of the network into 16-bit fixed points using a dynamic hierarchical quantization. Then, we design an operation module, which is the core computational part for processing. It is composed of convolution, sampling, and normalization units, which pipeline the inference calculation for each layer of the network. To achieve high-throughput inference computing, the processing elements group (PEG) array with local buffers is developed for convolutional computation. Based on the common components in encoding and decoding, the sampling and normalization units are compatible with codec computation and utilized for image compression with time-sharing multiplexing. According to the control signal, the operation module could change the order of data flow through the three units so that they perform encoding and decoding operations, respectively. Based on these design methods and schemes, DIC is deployed into the Xilinx Zynq ZCU104 development board to achieve high-throughput image compression at 6 different bit rates. The experimental results show that the processor can run at 200 MHz and achieve 283.4 GOPS for the 16 bits fixed-point DIC network. [ABSTRACT FROM AUTHOR]

RGB salient object detection (SOD) performs poorly in low-contrast and complex background scenes. Fortunately, the thermal infrared image can capture the heat distribution of scenes as complementary information to the RGB image, so the RGB-T SOD has recently attracted more and more attention. Many researchers have committed to accelerating the development of RGB-T SOD, but some problems still remain to be solved. For example, the defective sample and interfering information contained in the RGB or thermal image hinder the model from learning proper saliency features, meanwhile the low-level features with noisy information result in incomplete salient objects or false positive detection. To solve these problems, we design a cross-modal attention enhancement network (CAE-Net). First, we concretely design a cross-modal fusion (CMF) module to fuse cross-modal features, where the cross-attention unit (CAU) is employed to enhance the two modal features, and channel attention is used to dynamically weigh and fuse the two modal features. Then, we design the joint-modality decoder (JMD) to fuse cross-level features, where the low-level features are purified by higher level features, and multi-scale features are sufficiently integrated. Besides, we add two single-modality decoder (SMD) branches to preserve more modality-specific information. Finally, we employ a multi-stream fusion (MSF) module to fuse three decoders' features. Comprehensive experiments are conducted on three RGB-T datasets, and the results show that our CAE-Net is comparable to the other methods. [ABSTRACT FROM AUTHOR]

Background: Ovarian cancer (OC) is one of the most malignant tumors in the female reproductive system, with a poor prognosis. Various responses to treatments including chemotherapy and immunotherapy are observed among patients due to their individual characteristics. Applicable prognostic markers could make it easier to refine risk stratification for OC patients. Autophagy is closely implicated in the occurrence and development of tumors, including OC. Whether autophagy -related genes can be used as prognostic markers for OC patients remains unclear. Methods: The gene transcriptome data of 374 OC patients were downloaded from The Cancer Genome Atlas (TCGA) database. The correlation between the autophagy levels and outcomes of OC patients was identified through the single sample gene set enrichment analysis (ssGSEA). Recognized molecular markers of autophagy in different clinical specimens were detected by immunohistochemistry (IHC) assay. The gene set enrichment analysis (GSEA), ESTIMATE, and CIBERSORT analysis were applied to explore the correlation of autophagy with the tumor immune microenvironment (TIME). Single-cell RNA-sequencing (scRNA-seq) data from seven OC patients were included for characterizing cell-cell interaction patterns of autophagy-high or low tumor cells. Machine learning, Stepwise Cox regression and LASSO-Cox analysis were used to screen autophagy hub genes, which were used to establish an autophagy-related signature for prognosis evaluation. Four tumor immunotherapy cohorts were obtained from the GEO (Gene Expression Omnibus) database and the literature for autophagy risk score validation. Results: The autophagy levels were closely related to the prognosis of the OC patients. Additionally, the autophagy levels were correlated with TIME status including immune score, and immune-cell infiltration. The scRNA-seq analysis found that tumor cells with high or low autophagy levels had different interactions with immune cells, especially macrophages. Eight autophagy-hub genes (ZFYVE1, AMBRA1, LAMP2, TRAF6, PDPK1, ATG2B, DAPK1 and TP53INP2) were screened for an autophagy-related signature. According to this signature, higher risk score was correlated with poor prognosis and better immunotherapy response in the OC patients. Conclusions: The autophagy-related signature is applicable to predict the prognosis and immune checkpoint inhibitors (ICIs) therapy efficiency in OC patients. It is possible to identify OC patients who will respond to ICIs therapy and have a favorable prognosis, although more verification is needed. [ABSTRACT FROM AUTHOR]

Simple Summary: Due to most traditional high-throughput experiments are tedious and laborious in identifying potential protein–protein interaction. To better improve accuracy prediction in protein–protein interactions. We proposed a novel computational method that can identify unknown protein–protein interaction efficiently and hope this method can provide a helpful idea and tool for proteomics research. Protein–protein interactions (PPIs) play an essential role in many biological cellular functions. However, it is still tedious and time-consuming to identify protein–protein interactions through traditional experimental methods. For this reason, it is imperative and necessary to develop a computational method for predicting PPIs efficiently. This paper explores a novel computational method for detecting PPIs from protein sequence, the approach which mainly adopts the feature extraction method: Locality Preserving Projections (LPP) and classifier: Rotation Forest (RF). Specifically, we first employ the Position Specific Scoring Matrix (PSSM), which can remain evolutionary information of biological for representing protein sequence efficiently. Then, the LPP descriptor is applied to extract feature vectors from PSSM. The feature vectors are fed into the RF to obtain the final results. The proposed method is applied to two datasets: Yeast and H. pylori, and obtained an average accuracy of 92.81% and 92.56%, respectively. We also compare it with K nearest neighbors (KNN) and support vector machine (SVM) to better evaluate the performance of the proposed method. In summary, all experimental results indicate that the proposed approach is stable and robust for predicting PPIs and promising to be a useful tool for proteomics research. [ABSTRACT FROM AUTHOR]

The rapidly growing location-based social network (LBSN) has become a promising platform for studying users' mobility patterns. Many online applications can be built based on such studies, among which, recommending locations is of particular interest. Previous studies have shown the importance of spatial and temporal influences on location recommendation; however, most existing approaches build a universal spatial–temporal model for all users despite the fact that users always demonstrate heterogeneous check-in behavior patterns. In order to realize truly personalized location recommendations, we propose a Gaussian process based model for each user to systematically and non-linearly combine temporal and spatial information to predict the user's displacement from their currently checked-in location to the next one. The locations whose distances to the user's current checked-in location are the closest to the predicted displacement are recommended. We also propose an enhancement to take into account category information of locations for semantic-aware recommendation. A unified recommendation framework called spatial–temporal–semantic (STS) is introduced to combine displacement prediction and the semantic-aware enhancement to provide final top-N recommendation. Extensive experiments over real datasets show that the proposed STS framework significantly outperforms the state-of-the-art location recommendation models in terms of precision and mean reciprocal rank (MRR). [ABSTRACT FROM AUTHOR]