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There has always been a specific focus on nitrogen fertilization in sugar beet production due to its important effect on sugar beet root yield and quality. For stable sugar beet growth and satisfactory root yield and quality, balanced N fertilization is crucial. Thus, this study aimed to investigate spring N fertilization in two seasons as the following treatments: N0—control, N1—only pre-sowing fertilization, and N2—pre-sowing with topdressing. Four different genotypes were included in the study (Serenada, Colonia, Fred, and Danton). The experiment was set up in a plain area, belonging to the temperate climate zone in Eastern Croatia (Županja and Vrbanja), with the long-term mean (LTM) (March–October) air temperature around 16 °C and the total precipitation of 515 mm. Pre-sowing N fertilization had a smaller impact on root yield in the year with higher precipitation (31% higher than LTM). Therefore, the average yields with pre-sowing fertilization (N1) and pre-sowing fertilization with top dressing (N2) were very similar and were only 7% higher than those of the control. In a season with less rainfall (29% less than LTM), pre-sowing fertilization with top dressing (N2) had a more pronounced effect on the increase in sugar beet root yield, which was 17% higher compared to that of the control treatment. The sugar beet sucrose content and quality parameters (brei impurities, loss of sugar in molasses, extractable sugar) differed when N fertilization was applied among locations in both seasons. The white sugar yield was the highest at N2 treatment with pre-sowing and topdressing N fertilization. In general, according to the average of all locations and years of research, the Serenada hybrid achieved the highest average root yield (81.1 t ha−1), while Colonia exhibited the highest root sugar content (14.5%) and white sugar yield (9.7 t ha−1). [ABSTRACT FROM AUTHOR]

During intrauterine life, external stimuli including maternal nutrition, lifestyle, socioeconomic conditions, anxiety, stress, and air pollution can significantly impact fetal development. The human brain structures begin to form in the early weeks of gestation and continue to grow and mature throughout pregnancy. This review aims to assess, based on the latest research, the impact of environmental factors on fetal and neonatal brain development, showing that oxidative stress and inflammation are implied as a common factor for most of the stressors. Environmental insults can induce a maternal inflammatory state and modify nutrient supply to the fetus, possibly through epigenetic mechanisms, leading to significant consequences for brain morphogenesis and neurological outcomes. These risk factors are often synergic and mutually reinforcing. Fetal growth restriction and preterm birth represent paradigms of intrauterine reduced nutrient supply and inflammation, respectively. These mechanisms can lead to an increase in free radicals and, consequently, oxidative stress, with well-known adverse effects on the offspring's neurodevelopment. Therefore, a healthy intrauterine environment is a critical factor in supporting normal fetal brain development. Hence, healthcare professionals and clinicians should implement effective interventions to prevent and reduce modifiable risk factors associated with an increased inflammatory state and decreased nutrient supply during pregnancy. [ABSTRACT FROM AUTHOR]

How crop biodiversity adapts to drought conditions and enhances grain yield became the most important issue facing agronomists and plant breeders at the turn of the century. Variations in genetic response, inadequacy of nutrients in the soil, and insufficient access to nutrients are factors that aggravate drought stressors. The development of screening tools for identifying drought tolerance is important in the deployment of durum wheat varieties suited to drought-prone environments. An experiment was conducted to evaluate durum wheat varieties under a range of nutrient supplies in naturally imposed drought conditions. The treatments consisting of two nitrogen regimes (i.e., control and 60 kg ha−1), four durum wheat varieties, and three types of nutrients (control, sulfur, and zinc) that were arranged in a split-split plot design with three replications. Both foliar-based sulfur and zinc fertilization were employed at the flag leaf stage, at a rate of 4 and 3-L ha−1, respectively. The results showed a significant (p < 0.05) genetic variation in chlorophyll concentration, grain protein content, tillering potential, and leaf area index. Varieties that contained better leaf chlorophyll content had improved grain yield by about 8.33% under 60 kg/ha nitrogen. A combined application of nitrogen and zinc at flag leaf stage significantly improved grain yield of Duragold by about 21.3%. Leaf chlorophyll content was found to be a more important trait than spikes per m2 to discriminate durum wheat varieties. Foliar application of sulfur increased the grain yield of drought-stressed plants by about 12.23%. Grain yield and protein content were strongly correlated with late-season SPAD readings. Significant (p < 0.05) correlation coefficients were obtained between normalized difference vegetation index, leaf area index, grain yield, and protein content with late-season chlorophyll content, revealing the importance of chlorophyll content in studying and identifying drought-tolerant varieties. [ABSTRACT FROM AUTHOR]

In this study, we propose a set of nonlinear differential equations to model the dynamic growth of avascular stage tumors, considering nutrient supply from underlying tissue, innate immune response, contact inhibition of cell migration, and interactions with a chemotherapeutic agent. The model has been validated against available experimental data from the literature for tumor growth. We assume that the size of the modeled tumor is already detectable, and it represents all clinically observed existent cell populations; initial conditions are selected accordingly. Numerical results indicate that the tumor size and regression significantly depend on the strength of the host immune system. The effect of chemotherapy is investigated, not only within the malignancy, but also in terms of the responding immune cells and healthy tissue in the vicinity of a tumor. [ABSTRACT FROM AUTHOR]

Winter wheat is one of the most important crops globally and also in Hungary. Hungary has excellent crop production potential including seed production. The aim of our experiment is to determine the effects of different amounts and proportions of nutrients and those of the seed size of winter wheat in laboratory seed tests on the seed parameters (germination percentage, germination power, seedling health and vigour), as well as in field tests of the seed parameters (emergence percentage and yield of next crop year). Laboratory seed tests of winter wheat variety GK Petur were conducted with seeds that underwent ten nutrient treatments and of three seed size fractions over four crop years, together with field experiments in three growing seasons. Compared to the untreated control group, N treatments significantly decreased the health of the seedlings in the next generation of winter wheat. PK treatments without N increased the germination percentage, vigour value and emergence percentage significantly, but the health of the seedlings decreased. In contrast, NPK treatments with a ratio of 2:1:1 improved all the tested parameters compared to those of the control group. The increase in seed sizes significantly increased the germination power, seedling health, vigour value, emergence percentage and the yield of the next crop year. It can be concluded that the factors of nutrient supply, crop year of the seed production and the seed size significantly influence the quality of the seed (germination percentage, germination power, seedling health, vigour and emergence percentage), thus also the yield of the next generation. [ABSTRACT FROM AUTHOR]

A plant-based diet (PBD) can provide numerous health benefits for patients with cardiovascular risk factors. However, an inadequately planned PBD also bear the potential for deficiencies in certain macro- and micronutrients. The present study analyzed nutrient profiles of individuals who adopted a PBD as part of the CardioVeg study. Participants with cardiovascular risk factors were randomly assigned to either a whole-food PBD intervention (n = 36; eight 90 min group meetings including two 120 min cooking sessions) or a control group asked to maintain an omnivorous diet (n = 34) for eight weeks. Food intake data were collected using three-day weighed food records and analyzed with NutriGuide software, including the German Nutrient Data Base (German: Bundeslebensmittelschlüssel). Nutrient intake was compared before and after eight weeks as well as between the groups. The results for both groups were then contrasted to the current dietary recommendations published by the societies for nutrition in Germany, Austria, and Switzerland. Moreover, anthropometric/laboratory data and ambulatory blood pressure monitoring were determined at baseline and after 8 weeks. Data of a subsample (n = 18 in the PBD group and n = 19 in the control group) were used for the present analyses of the dietary intake data. A PBD yielded several benefits including (but not limited to) a lower energy density, a lower intake of cholesterol and saturated fat, an increased consumption of fiber, and a lower intake of salt. Recommended intakes of most vitamins and minerals were generally met, except for vitamin B12 in the PBD group. A low intake of several other critical nutrients (vitamin D, iodine) was observed in both groups. Compared with the control group, PBD resulted in a significant decrease in body weight, body mass index, waist circumference, HbA1c, and fasting blood glucose after 8 weeks. Overall, it can be concluded that a PBD had a more favorable nutrient composition for cardiovascular health than the omnivorous dietary pattern of the control group. [ABSTRACT FROM AUTHOR]

The flowering time of tree peony is short and concentrated in spring, which limits the development of its industry. We previously achieved tree peony reflowering in autumn. Here, we further shifted its reflowering time ahead through proper gibberellin (GA) treatment plus nutrient supply. GA treatment alone initiated bud differentiation, but it aborted later, whereas GA plus nutrient (G + N) treatment completed the opening process 38 days before the control group. Through microstructural observation of bud differentiation and starch grains, we concluded that GA plays a triggering role in flowering induction, whereas the nutriment supply ensured the continuous developing for final opening, and both are necessary. We further determined the expression of five floral induction pathway genes and found that PsSOC1 and PsLFY probably played key integral roles in flowering induction and nutrient supply, respectively. Considering the GA signaling, PsGA2ox may be mainly involved in GA regulation, whereas PsGAI may regulate further flower formation after nutrient application. Furthermore, G + N treatment, but not GA alone, inhibited the expression of PsTPS1, a key restricting enzyme in sugar signaling, at the early stage, indicating that sugar signaling is also involved in this process; in addition, GA treatment induced high expression of PsSnRK1, a major nutrient insufficiency indicator, and the induction of PsHXK1, a rate-limiting enzyme for synthesis of sugar signaling substances, further confirmed the nutrient shortage. In short, besides GA application, exogenous nutrient supply is essential to shift tree peony reflowering ahead in autumn under current forcing culture technologies. [ABSTRACT FROM AUTHOR]

Vegetarian diets have gained popularity in sports. However, few data exist on the status of micronutrients and related biomarkers for vegetarian and vegan athletes. The aim of this cross-sectional study was to compare the micronutrient status of omnivorous (OMN, n = 27), lacto-ovo-vegetarian (LOV, n = 26), and vegan (VEG, n = 28) recreational runners. Biomarkers of vitamin B12, folate, vitamin D, and iron were assessed. Additionally, serum levels of calcium, magnesium, and zinc were examined. Lifestyle factors and supplement intake were recorded via questionnaires. About 80% of each group showed vitamin B12 adequacy with higher levels in supplement users. Mean red blood cell folate exceeded the reference range (>340 nmol/L) in all three groups (OMN: 2213 ± 444, LOV: 2236 ± 596, and VEG: 2354 ± 639 nmol/L; not significant, n.s.). Furthermore, vitamin D levels were comparable (OMN: 90.6 ± 32.1, LOV: 76.8 ± 33.7, and VEG: 86.2 ± 39.5 nmol/L; n.s.), and we found low prevalence (<20%) of vitamin D inadequacy in all three groups. Less than 30% of each group had depleted iron stores, however, iron deficiency anemia was not found in any subject. Our findings suggest that a well-planned, health-conscious lacto-ovo-vegetarian and vegan diet, including supplements, can meet the athlete’s requirements of vitamin B12, vitamin D and iron. [ABSTRACT FROM AUTHOR]

Nutrient stress has been known as the main limiting factor for maize growth and yield. Nitrapyrin, as a nitrification inhibitor—which reduces nitrogen loss—and foliar fertilizer treatments have been successfully used to enhance the efficiency of nutrient utilization, however, the impacts of these two technologies on physiological development, enzymatic responses, and productivity of maize are poorly studied. In this paper, the concentration of each stress indicator, such as contents of proline, malondialdehyde (MDA), relative chlorophyll, photosynthetic pigments, and the activity of superoxide dismutase (SOD) were measured in maize leaf tissues. In addition, biomass growth, as well as quantitative and qualitative parameters of yield production were examined. Results confirm the enhancing impact of nitrapyrin on the nitrogen use of maize. Furthermore, lower activity of proline, MDA, SOD, as well as higher photosynthetic activity were shown in maize with a more favorable nutrient supply due to nitrapyrin and foliar fertilizer treatments. The obtained findings draw attention to the future practical relevance of these technologies that can be implemented to enhance the physiological development and productivity of maize. However, this paper also highlights the importance of irrigation, as nutrient uptake from soil by the crops decreases during periods of drought. [ABSTRACT FROM AUTHOR]

The technical feasibility of valorizing tequila vinasse (TV), a wastewater with high pollution potential, through the production of biogenic hydrogen via dark fermentation, has long been proven in diverse lab-scale reactors that were operated either in batch or continuous mode. However, such systems have mainly been tested with diluted streams and nutrient supplementation, hindering the techno-economic attractiveness of the TV-to-hydrogen concept at large scale. In this study, the feasibility of producing hydrogen from high-strength undiluted TV with no added extra nutrients was evaluated under batch mesophilic conditions. Additionally, the use of two different acidogenic inocula obtained either by heat or heat-aeration pretreatment was investigated to get a greater understanding of the effect of inoculum type on the process. The results obtained showed that the TV utilized herein contained macro- and micro-nutrients high enough to support the hydrogenogenic activity of both cultures, entailing average hydrogen yields of 2.4–2.6 NL H2/L vinasse and maximum hydrogen production rates of 1.4–1.9 NL H2/L-d. Interestingly, the consumption of lactate and acetate with the concomitant production of butyrate was observed as the main hydrogen-producing route regardless of the inoculum, pointing out the relevance of the lactate-driven dark fermentative process. Clostridium beijerinckii was ascertained as key bacteria, but only in association with microorganisms belonging to the genera Enterobacter and Klebsiella, as revealed by phylogenetic analyses. [ABSTRACT FROM AUTHOR]

We tested six winter barley (Hordeum vulgare L.) cultivars in a small plot field experiment, measuring photosynthesis and other parameters three times during the growing season. Four genotypes—Andoria, Jakubus, Paradies and Zophia—are new, promising varieties with requirements of intensive technology, high yield potential and very good disease resistance. The two popular Hungarian varieties (KG Apavár and KG Puszta) are relatively old but they have good tolerance to extreme ecological conditions and outstanding resistance and winter hardiness. The aim of our research was to test the new varieties' performance. Several recent studies found close connections among various photosynthetic parameters in barley, and we confirmed that in our research. There were significant differences between the varieties in the assimilation rate—the highest values were measured at the BBCH 47–49 stage (end of booting), except Jakubus and Zophia, where the highest values were at BBCH 73–75 (milk ripe). The cultivars' response to irradiation change varied, especially at higher photosynthetic photon flux density (PPFD) levels. In April and May, the plants were in drought stress according to the intercellular CO2 level and the total conductance to carbon dioxide. The differences between the air and leaf temperature were also low, indicating water stress, but the assimilation rate was relatively high (9.07–14.09 µmol m−2 s−1).We found a close connection between normalized difference vegetation index (NDVI) values and grain protein content in each of the tested barley cultivars. The correlation was significant, at p = 0.01 level. The protein yield per hectare was determined rather by grain yield than protein content. The relationship between the NDVI values and grain yield was moderate, but NDVI values and protein content are in strong correlation. [ABSTRACT FROM AUTHOR]

The aim of our study was to analyse vegetables, potatoes and their products as sources of energy and nutrients in the average diet in Poland. Representative data of the 2016 Household Budget Survey from 36,886 households were used. This is the largest study sample in Poland, so we generalized the conclusions to the whole population using the statement 'average diet'. We analysed three main product groups: vegetables, vegetable products, and potatoes and potatoes products, dividing them into 14 subgroups (e.g., tomatoes, cabbage, carrots, other vegetables, and mushrooms). The percentages of energy, protein, carbohydrates, total fat, nine vitamins (thiamine, riboflavin, niacin, vitamin B6, folate, vitamin C, vitamin A, vitamin D, and vitamin E), seven minerals (calcium, phosphorus, sodium, potassium, iron, magnesium and zinc), and fibre from the analysed food subgroups are presented. Additionally, the influence of household characteristics on the supply of energy and nutrients from each subgroup of vegetables, potatoes, and their products was evaluated using cluster analysis. In the analysis, R programme and Kohonen neural networks were applied. Our study showed that vegetables, potatoes, and their products provide 7.3% of daily dietary energy supply. Vegetables contribute more than 20% of the supply of six nutrients: vitamin C (51.8%), potassium (32.5%), folate (31.0%), vitamin A (30.6%), vitamin B6 (27.8%), and magnesium (20.2%), as well as fibre (31.8%). Cluster analysis distinguished three clusters that differed in nutritional supply from vegetables, potatoes, and their products. Educational level, income measured by quintile groups, village size, socio-economic characteristics, urbanization degree, and land use were the most important factors determining differences between clusters.