1. Subacute Sclerosing Panencephalitis in Children: The Archetype of Non-Vaccination.
- Author
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Papetti L, Amodeo ME, Sabatini L, Baggieri M, Capuano A, Graziola F, Marchi A, Bucci P, D'Ugo E, Kojouri M, Gioacchini S, Marras CE, Nucci CG, Ursitti F, Sforza G, Ferilli MAN, Monte G, Moavero R, Vigevano F, Valeriani M, and Magurano F
- Subjects
- Child, Humans, Measles virus, Pandemics, Vaccination adverse effects, COVID-19 prevention & control, Measles epidemiology, Measles prevention & control, Subacute Sclerosing Panencephalitis epidemiology, Subacute Sclerosing Panencephalitis etiology, Subacute Sclerosing Panencephalitis prevention & control
- Abstract
Subacute sclerosing panencephalitis (SSPE) is a late complication of measles virus infection that occurs in previously healthy children. This disease has no specific cure and is associated with a high degree of disability and mortality. In recent years, there has been an increase in its incidence in relation to a reduction in vaccination adherence, accentuated by the COVID-19 pandemic. In this article, we take stock of the current evidence on SSPE and report our personal clinical experience. We emphasise that, to date, the only effective protection strategy against this disease is vaccination against the measles virus.
- Published
- 2022
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